Camelus dromedarius (Arabian camel): 105087555 Help Entry 105087555         CDS       T04642                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk04010   MAPK signaling pathway cdk04014   Ras signaling pathway cdk04015   Rap1 signaling pathway cdk04022   cGMP-PKG signaling pathway cdk04066   HIF-1 signaling pathway cdk04068   FoxO signaling pathway cdk04072   Phospholipase D signaling pathway cdk04150   mTOR signaling pathway cdk04151   PI3K-Akt signaling pathway cdk04152   AMPK signaling pathway cdk04211   Longevity regulating pathway cdk04213   Longevity regulating pathway - multiple species cdk04520   Adherens junction cdk04910   Insulin signaling pathway cdk04913   Ovarian steroidogenesis cdk04923   Regulation of lipolysis in adipocytes cdk04930   Type II diabetes mellitus cdk04931   Insulin resistance cdk04932   Non-alcoholic fatty liver disease cdk04960   Aldosterone-regulated sodium reabsorption cdk05010   Alzheimer disease cdk05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cdk00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105087555 (INSR)    04014 Ras signaling pathway     105087555 (INSR)    04015 Rap1 signaling pathway     105087555 (INSR)    04066 HIF-1 signaling pathway     105087555 (INSR)    04068 FoxO signaling pathway     105087555 (INSR)    04072 Phospholipase D signaling pathway     105087555 (INSR)    04022 cGMP-PKG signaling pathway     105087555 (INSR)    04151 PI3K-Akt signaling pathway     105087555 (INSR)    04152 AMPK signaling pathway     105087555 (INSR)    04150 mTOR signaling pathway     105087555 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     105087555 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105087555 (INSR)    04923 Regulation of lipolysis in adipocytes     105087555 (INSR)    04913 Ovarian steroidogenesis     105087555 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     105087555 (INSR)   09149 Aging    04211 Longevity regulating pathway     105087555 (INSR)    04213 Longevity regulating pathway - multiple species     105087555 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     105087555 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     105087555 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105087555 (INSR)    04932 Non-alcoholic fatty liver disease     105087555 (INSR)    04931 Insulin resistance     105087555 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cdk01001]     105087555 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:cdk04090]     105087555 (INSR) Enzymes [BR:cdk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      105087555 (INSR) Protein kinases [BR:cdk01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    105087555 (INSR) CD molecules [BR:cdk04090]  Proteins   105087555 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  105087555 NCBI-ProteinID:  XP_031292936 LinkDB All DBs Position 22:complement(5195565..5323414) Genome browser AA seq 1521 aa AA seqDB search MRAGPGPVARSRGRLPWPRRPICSGRGRAPSRGCSKGLSRAEAAARGPRRGREDARPPAP PAAAVEHVPSGPAPRALILRGPALPQPWAPGRAGGGGRAAAGGRCRAAGGRRGPPVPWRG PAGSGDATHVLLGSSPRSGVTGQPRTAKCLGCTQFGARVEGDGLEVAWGVPAVCPGMDIR NNLTRLHELANCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKD LFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWS RILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPT ICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCV NFSFCQDLHNKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHL LEGEKTIDSVTSAQELRGCTIVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSY ALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKL CLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSHDKILLKWEPYWP PDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPMRSNDPKSQNHPGWLMR GLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILK WKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQTE YEEAAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFIPRKSSSGPGAEDTRPSRRR RALADIGNGTAAVPTLPGFPNASSTSAPTSSEEHRPFEKVVSKESLVISGLRHFTGYRIE LQACNQDAPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLI VLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATY FYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLS ASDVFPCSVYVPDEWEVPREKIALLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNE SASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPE AENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMT RDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLS NEQVLKFVMDGGYLDQPDNCPDRVTNLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEV SFFHSEENKAPESEELDMEFEDMESVPLDRSAHSQREEAGGRDAGSALGLKRGYEEHIPY THMNGGKRNGRILTLPRSDPS NT seq 4566 nt NT seq  +upstreamnt  +downstreamnt atgcgggcggggcccgggccagtggctcggagtcggggccgcctcccgtggccgcgccgc ccgatctgcagcggccgaggccgcgccccctcccgaggctgctccaagggcctctcccgg gcggaggctgcggcccgcgggccgcggcgtggacgagaggacgcgcggcccccagcgcct ccggcggccgccgtggagcatgtccccagcgggccggcgccgcgcgctctgatcctccgg ggccccgcgctcccgcagccatgggcgccggggcgggcggggggcggcggccgtgccgct gctggtggccgttgccgcgctgctggtgggcgccgcgggccacctgtaccctggagaggc ccagctggctccggagacgcgacacacgtcctcttgggttcgtctccgagaagcggggtc actggacagcctcggacagccaaatgcctggggtgcacacagtttggagccagagtcgag ggagacggactggaggtcgcctggggggtcccagctgtgtgccccggcatggacatccgg aacaacctcacccggctgcacgagctggccaactgctccgtcatcgaaggacatctgcag atactgctgatgttcaaaacgaggcctgaggatttccgagacctcagtttccccaaactc atcatgatcaccgattacttgctgctcttccgggtctacgggctggagagcctgaaggac ctgttccccaacctcacggtcatccggggctcccgcctcttcttcaactacgcgctggtc atcttcgagatggttcacctgaaggagcttggcctctacaatttgatgaacattacgcgg ggctcggtccgcatcgagaagaacaatgagctctgctacctggccaccatcgactggtcg cgcatcctggactccgtggaggataattacatcgtgctgaacaaagatgacaacgaggaa tgtggggacatttgtccaggcactgccaagggcaaaaccaactgccctgccactgtcatc aatgggcaatttgtcgagcggtgttggacgcacagccactgtcagaaagtttgtccgacc atctgcaagtcgcacggctgcaccgcagagggcctctgctgccacagcgagtgcttgggt aactgctccgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctggac ggccgctgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgcgtg aacttcagcttctgccaggatctgcacaacaaatgcaagaactctcggaggcagggctgc caccagtacgtcattcacaataacaagtgcatccctgagtgtccctctgggtacacgatg aattccagcaacttgatgtgcactccatgcctgggcccctgtcccaaggtctgccacctc ctggaaggtgagaagaccatcgactcagtgacgtccgcccaggagctccgaggctgcacc attgtcaacgggagcttaatcatcaacattcgagggggcaacaatctggcagctgagctg gaggccaaccttggactcattgaagaaatttcagggtacctgaaaatccgccggtcctac gccctcgtgtcactttccttcttccggaagttacgtctgattcgaggagagaccttggag attgggaactactccttctacgccttggacaaccagaacctaaggcagctgtgggactgg agcaaacacaacctcaccatcacgcaggggaaactgttcttccactataaccccaagctc tgcttgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggagaga aacgacattgccctgaagaccaatggggaccaggcgtcctgtgaaaatgaattacttaaa ttctcttacattcggacatctcatgacaagatcttgctgaaatgggagccctactggccc cctgacttccgagatctcttggggttcatgcttttctacaaagaggccccttatcagaac gtgacggagttcgatggacaggatgcgtgcggctccaacagctggacggtggtggacatt gacccgccgatgaggtccaatgaccccaagtcacagaaccaccccgggtggctgatgcgg ggtctcaagccctggacccagtacgccatctttgtcaagaccttggtcaccttttctgac gaacgccgcacgtacggggccaagagcgacatcatctatgtccagacagatgccactaat ccttccgtcccgctggatcccatctcggtttctaattcctcgtcccagattattctgaag tggaagcctccctctgaccccaacggcaacatcacacactacctggttttctgggagagg caggcggaagacagcgagctgtatgaattggattattgcctcaaagggctgaagctgccg tcccggacctggtctccgccgtttgagtctgagggctcccagaagcacaatcagaccgag tacgaggaggctgccggagagtgctgctcctgcccgaagaccgactctcagatcctgaag gagctggaggaatcctcgttccggaagacatttgaggattacctgcacaatgtggttttc atccccagaaaatcctcttcaggccctggcgcggaggacaccaggccgtcgcggagacgc agggccctggctgacatagggaatggcacagcggccgtgcccacgctcccggggttcccc aacgcctcctccaccagcgcacccaccagctcagaggagcacagacccttcgagaaagtg gtgagcaaagagtcactggtcatctcggggctgcgtcactttaccggctaccgcatcgag ctgcaggcttgcaaccaagatgcccccgaggagcggtgcagcgtggccgcctacgtcagc gccaggaccatgcccgaagccaaggccgatgatattgtgggccccgtgacccacgaaatc ttcgagaacaacgtcgtccacctgatgtggcaggagcccaaggaacccaacggtctgatc gtgctctatgaagtgagctaccgacgatacggcgatgaggagctgcacctgtgcgtctct cgaaggcatttcgctctggagcggggctgcaggctgcgcgggctgccgcccgggaattac agcgtgagagttcgggccacctccctggcgggcaacggctcctggacagaagccacttat ttctatgtgacagattatttagacgtcccatcaaatattgcaaagattatcatcggcccc ctcatctttgtgtttctcttcagtgttgtgattgggagtatttatctgttcctgagaaag aggcagccggatgggccactgggaccactgtatgcttcttcgaaccccgagtacctcagt gccagcgatgtgttcccgtgttctgtgtacgtgccggacgagtgggaggtgccccgggag aagatcgcgctgctgcgagagctcgggcagggctccttcggcatggtgtacgagggcaac gccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacggtcaacgag tcggccagcctgcgagaacggattgagtttctcaacgaggcctcggtcatgaagggcttc acctgccaccacgtggtccgcctcctgggggtggtgtccaaaggccagccgacactggtg gtgatggagttgatggctcacggagacttaaagagctacctccgttccctgcggccggag gccgagaataaccctggtcgccctccccctacgctgcaagagatgattcagatggcggcg gagattgccgatgggatggcgtacctgaacgccaagaagttcgtgcaccgggacctcgca gctcggaactgcatggtcgctcatgattttaccgtcaaaatcggagactttggaatgacc agagacatctacgaaacggactactaccggaaagggggcaagggcctgctccccgtgcgg tggatggcacccgaatccctgaaggacggggtcttcaccacttcttccgacatgtggtcc ttcggcgtggtcctctgggaaattaccagcttggcagaacagccttaccaaggcctatct aatgagcaggtgttgaaattcgtcatggatggagggtatctggatcaacctgacaactgt ccagacagagtcaccaacctgatgcgcatgtgctggcagttcaaccccaagatgcggccg accttcctggagatcgtcgacctgctcaaggacgacctgcaccccagctttcccgaagtt tccttcttccacagcgaggagaacaaggcgccggagagcgaggagctggacatggagttt gaggacatggagagcgtcccgctggaccggtcggcacactcgcagcgggaggaggccggg ggccgggacgcggggtcggcgctggggctgaagcggggctacgaggagcacatcccctac acccacatgaacgggggcaagaggaacggccgcatcctgaccctgccgcggtccgaccct tcctaa

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