Camelus dromedarius (Arabian camel): 105095309
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Entry
105095309 CDS
T04642
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk00010
Glycolysis / Gluconeogenesis
cdk00020
Citrate cycle (TCA cycle)
cdk00620
Pyruvate metabolism
cdk00785
Lipoic acid metabolism
cdk01100
Metabolic pathways
cdk01200
Carbon metabolism
cdk01210
2-Oxocarboxylic acid metabolism
cdk04066
HIF-1 signaling pathway
cdk04922
Glucagon signaling pathway
cdk05230
Central carbon metabolism in cancer
cdk05415
Diabetic cardiomyopathy
Module
cdk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105095309 (PDHA1)
00020 Citrate cycle (TCA cycle)
105095309 (PDHA1)
00620 Pyruvate metabolism
105095309 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105095309 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105095309 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105095309 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105095309 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105095309 (PDHA1)
Enzymes [BR:
cdk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105095309 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
105095309
NCBI-ProteinID:
XP_031301642
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All DBs
Position
X:complement(106394052..106411176)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSSLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYCSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaacgatgctacatttgaaattaagaaa
tgcgatcttcaccggctggaagagggccctcctgtcactacggtgcttaccagggaggac
gggctcaaatactaccggatgatgcagactgtgcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacctgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggctggaataaaccccacagaccatctgatcacagcctaccgggct
catggctttacctttactcgtgggctttctgtccgagaaattctcgcagaacttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtatgccaagaacttc
tacgggggcaatggcattgtgggagctcaggtgcccttgggagctgggattgctttggcc
tgtaagtataatggaaaagatgaggtctgtttgactttgtatggcgatggtgctgctaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaagttgccttgtattttc
atctgtgagaataaccgctatgggatgggaacatctgtggagagggcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgagaggccacgaggtttgcagctgcctattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccacggacacagcatgagcgatcccggagtcagt
tatcgtacacgagaagaaatacaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggataggatggtgaacagcagtcttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgctacagccgatcctgaaccgcct
ttggaagaactcggctatcacatctactgtagtgatccgccttttgaagtccggggtgca
aaccagtggatcaagtttaaatccatcagttaa
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