Canis lupus familiaris (dog): 488448
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Entry
488448 CDS
T01007
Symbol
GLS
Name
(RefSeq) LOW QUALITY PROTEIN: glutaminase kidney isoform, mitochondrial isoform X2
KO
K01425
glutaminase [EC:
3.5.1.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00220
Arginine biosynthesis
cfa00250
Alanine, aspartate and glutamate metabolism
cfa00470
D-Amino acid metabolism
cfa01100
Metabolic pathways
cfa04724
Glutamatergic synapse
cfa04727
GABAergic synapse
cfa04964
Proximal tubule bicarbonate reclamation
cfa05206
MicroRNAs in cancer
cfa05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
488448 (GLS)
00220 Arginine biosynthesis
488448 (GLS)
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
488448 (GLS)
09150 Organismal Systems
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
488448 (GLS)
09156 Nervous system
04724 Glutamatergic synapse
488448 (GLS)
04727 GABAergic synapse
488448 (GLS)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
488448 (GLS)
05230 Central carbon metabolism in cancer
488448 (GLS)
Enzymes [BR:
cfa01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.2 glutaminase
488448 (GLS)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glutaminase
EF-hand_14
Ank_4
Ank_2
Ank
Ank_3
Ank_5
Motif
Other DBs
NCBI-GeneID:
488448
NCBI-ProteinID:
XP_545570
Ensembl:
ENSCAFG00000009513
VGNC:
41276
LinkDB
All DBs
Position
37:2381805..2456538
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AA seq
680 aa
AA seq
DB search
MMRLRGSAMLRDLLLRPPAAACAALRRPQPLAAQCRRARGGGPAAARLLPRWGGGAGGAG
GGVRPAGPPARGLSGSPSEILQELGKGGPQPPQPPQPPQPPQPGASPPAAPSAPGPQDGP
GEADAFGNSEGKELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLR
TSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTS
HIDELFESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVK
PLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGV
NNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVG
ILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFS
GQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHN
YDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTA
LHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQ
GDADDGKENQTVHKNLDGLL
NT seq
2043 nt
NT seq
+upstream
nt +downstream
nt
atgatgcggctgcggggctcggcgatgctgcgagacctgctcctgcggcctcccgccgcc
gcctgcgccgccctcaggcggccacagccgctcgccgcgcagtgccggcgtgcccggggc
gggggcccggcggccgcgcggctgctcccgcggtggggcgggggcgcgggcggcgcgggc
gggggcgtccggccggcggggccccccgcgcggggcctgtcgggctccccgtcggagatc
ctgcaggagctgggcaagggcggcccgcagcccccgcagcccccgcagcccccgcagccc
ccgcagcccggggcgtcgccgcccgccgcgccgtcggctcccggcccccaggacggcccc
ggggaggcggacgcgttcggcaacagcgagggcaaggagctcgtggcctcgggcgaaaat
aaaataaaacagggtctattacctagcttggaagatttgctgttctatacaattgcagaa
ggacaagagaaaatacctgttcataaatttattacagcactcaaatctacaggattgcga
acgtctgatcccaggttgaaagagtgtatggatatgttaagattaactcttcaaacaaca
tcagatggtgtcatgctagacaaagatctttttaaaaaatgtgttcagagcaacattgtt
ttgttgacacaagcctttagaagaaagtttgtcattcctgactttatgtcttttacctct
cacattgatgagttatttgaaagtgctaaaaagcagtctggaggaaaggttgcagattat
attcctcagctagccaagttcagtcctgatttgtggggtgtgtctgtgtgtacagtagat
ggacagaggcattctattggagataccaaagttccattttgtcttcagtcctgtgtaaaa
cctttgaaatatgccattgctgttaatgatcttggaacagaatatgtgcatcgatatgtt
gggaaagagccaagtggattaagattcaacaaactgtttttaaatgaagatgataagcca
cacaatcctatggtaaatgctggagcaattgttgtgacttcattaataaagcaaggagtg
aataatgctgaaaaatttgactatgtgatgcagtttttgaataagatggctggcaatgaa
tatgttggattcagtaatgcaacgtttcagtctgaaagagaaagtggagatagaaatttt
gcaataggatattacctgaaagaaaaaaagtgttttccagaaggcacagacatggttggt
atattagacttctatttccagctatgctccattgaagtaacttgtgaatcagccagcgtg
atggctgcaacactggctaatggtggtttctgtccaattactggtgagagagtactgagc
cctgaagcagttcgaaatactctaagtttgatgcattcctgtggcatgtatgatttctca
gggcagtttgccttccatgttggtcttcctgcaaaatctggagttgctgggggcattctt
ttagttgtccccaatgtcatgggcatgatgtgctggtctcctcctctggataagatgggc
aacagtgttaagggaattcacttctgtcatgatcttgtttctctctgtaatttccataac
tatgataatctgagacactttgcaaaaaaacttgatcctcgaagagaaggtggtgatcaa
agggtgaagtcagtgataaaccttttgtttgccgcgtacaccggggacgtgtctgcactg
cgaaggttcgctctgtcggccatggacatggagcagcgggactacgactcgaggacggcg
ctgcacgtcgcggccgcagagggtcacgtcgaagtcgtcaaattcctgctggaagcgtgc
aaggtgaacccgttccccaaggacaggtggaacaacactcccatggatgaggcgctgcac
ttcgggcaccacgacgtgtttaagatcctccaggagtaccaagtgcagtacacgccccag
ggggatgccgacgacgggaaggaaaatcagacggtccacaagaacctggacggactcttg
taa
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