Camelus ferus (Wild Bactrian camel): 102521580
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Entry
102521580 CDS
T02979
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
cfr
Camelus ferus (Wild Bactrian camel)
Pathway
cfr00230
Purine metabolism
cfr01100
Metabolic pathways
cfr04927
Cortisol synthesis and secretion
cfr04934
Cushing syndrome
cfr05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
cfr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102521580 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
102521580 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102521580 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102521580 (PDE8B)
Enzymes [BR:
cfr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
102521580 (PDE8B)
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Motif
Pfam:
PDEase_I
PDE8
PAS
PAS_9
PAS_3
PAS_4
PAS_8
Motif
Other DBs
NCBI-GeneID:
102521580
NCBI-ProteinID:
XP_032330520
UniProt:
A0A8B8SKZ7
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Position
3:51013208..51300246
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AA seq
885 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPRQTTGVSQGLAAPLHGLFVQTDAADAIPPSRASR
PRGATRVRRARAELGSGSSAGSAALAATTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSQASGDCEEASVLPLLHEGFNRRFME
NNSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPALER
MMGYPKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDSNKQIHKIHRDSGDNSQTESLSFRYKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITI
NDVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKIFSRFGVCEFLHCSETTLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMGAEIEGSDCECNPIGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPTDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccggcgtgtcgcagggcctcgcggcccccctg
cacggcctcttcgtccagaccgacgccgccgacgccatcccaccgagccgcgcttccagg
ccccgcggcgccacccgcgtccgcagggcccgcgccgagctgggcagcggcagcagcgcg
ggctccgcagccctcgccgcgaccacctgcaggggccggaggcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtcaagcaggtctcttctgcggaggtg
cgcatcgggcccatgagactgacgcaggatcctatccaggttttgctgatctttgcaaag
gaagacagtcagagtgatgggttctggtgggcctgtgacagagccggctacaggtgcaat
atcgctcggactccagagtcagccctggaatgctttctagataaacatcatgaaattatt
gtcatcgatcacagacaaactcaaaacttcgatgcggaagcagtgtgcaggtcgatccgg
gccacaaatccctccgagcacacggtgatcctcgcagtggtttcacaagcatcaggcgac
tgtgaagaggcctcagtcctccctcttctgcacgaaggcttcaacaggagatttatggag
aataacagcataattgcttgctataatgaactgatccaaatagaacatggggaagttcgc
tcacagttcaagttaagggcctgtaattcagtgtttacagcattagaccactgtcatgaa
gccatagaaataacaagtgatgaccacgtgatccagtatgtcaacccagccctcgaaagg
atgatgggctaccccaagggcgagctcctggggaaagaactcgctgagctccccaaaagc
gataagaaccgggcagaccttctcgacaccatcaacacctgcatcaagaagggcaaggag
tggcagggggtttactatgccagacggaaatcgggggacagcatccaacagcatgtgaag
atcactccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactg
tgttgtaccaccgacagtaataagcagattcacaagattcatcgtgattcaggagacaat
tctcagacagagtctctttcattcagatacaagaacaggaggaaagagtccattgatgtg
aagtcaatatcatctcgaggcagtgatgcaccaagtctacagaatcgtcgctacccatcc
atggcgaggattcattccatgactatcgaggctcccatcacaaaggttataaatataatc
aatgcagcccaagaaaatagtcctgtcacagtagcagaagccttggacagagttttagaa
attttacggaccacagaactatactcccctcagctgggtaccaaagatgaagaccctcac
accagtgacctcgtgggaggcctgatgactgatggcttgagaaggttgtcaggaaatgag
tatgtgttcactaagaacgtgcaccagagtcacagtcaccttgcgatgccaataaccatc
aatgacgtccctccttctattgctcaattacttgataatgaggaaagctgggagttcaac
atctttgaactggaagctgtgacacataaaaggccattggtttacctgggcttaaagatc
ttttcccggtttggagtatgtgagtttttacactgttctgaaactactctgcgggcctgg
ctgcaagtgattgaagccaactaccactcctccaacgcttaccacaactccacccacgcc
gctgacgtgctgcacgccaccgccttcttcctcggaaaggagagagtaaagggaagcctc
gatcagctagatgaggtggctgctctgattgctgccacagtccacgacgtggatcacccg
ggaaggaccaattctttcctgtgcaatgcaggcagtgaactcgccgtgctctataatgac
accgctgtcttggagagtcatcacacagccttggccttccagctcacggtcaaggacagc
aaatgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
attgacatggttttagcaacagaaatgacaaaacacttcgaacatgtgaacaaatttgtg
aacagcatcaacaagccaatgggagctgagattgaaggcagcgactgtgaatgcaaccct
attgggaagaactttcctgaaaaccaaatcctgatcaagcgcatgatgattaaatgtgct
gacgtggccaacccatgccgccccctggacctgtgcatcgaatgggctgggaggatctct
gaggagtacttcgcacagactgatgaagagaagagacaggggctacctgtggtgatgcca
gtgtttgaccggaatacctgtagcatccccaagtcccaaatctccttcattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcccacctgccagccctgatgcaacat
ttggccgataactacaaacactggaagacattagatgacctaaagtgcaaaagtctgagg
cttccaactgacagctaa
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