Cricetulus griseus (Chinese hamster): 100761447
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Entry
100761447 CDS
T02813
Symbol
Srd5a1
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X2
KO
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00140
Steroid hormone biosynthesis
cge01100
Metabolic pathways
Module
cge_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
cge_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100761447 (Srd5a1)
Enzymes [BR:
cge01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
100761447 (Srd5a1)
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Gene cluster
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
100761447
NCBI-ProteinID:
XP_027255921
UniProt:
A0A9J7FC01
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Position
2:complement(364682945..364713366)
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AA seq
347 aa
AA seq
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MGSSPRSREGWALCVGGALCNRTLPWNPCGRALSGGVSSWSSPRPNRWLAPPLGRYALPG
PWLEWAALCPPPGLICGSAWKPRYGARCSTSAMDLDESRLLDSLTYLEGLLALVVFALLT
FVGSPYGRYSSQHPGLQVPARPAWFLQELPSMAWPLYEYARPAAARLGSLPNRVLLAMFL
THYVQRTLVFPVLIRGGKPTPLFSFAAAILFCTFNGYLQSRYLSQFAVYAEDWVAHPCFL
IGFALWLAGMVINIHSDHILRNLRKPGETGYKIPRGGLFEYVSAANYFGEITEWCGFALA
SGSPQAGVFALFTFSALFTRAKQHHQWYHEKFEDYPKSRKMLIPFVL
NT seq
1044 nt
NT seq
+upstream
nt +downstream
nt
atgggtagctctccccgatcgcgggagggctgggctctttgcgtaggcggggctctgtgc
aatcggactctgccttggaacccctgcgggagggcactgtctggtggtgttagctcgtgg
tccagtccccgcccgaacaggtggctcgcccctcccctgggcaggtacgcgctgccgggg
ccctggctggagtgggccgctctgtgccctcctcctgggcttatatgtggctctgcttgg
aagcccaggtatggagcacgctgctcgacctcagctatggacttggacgagtcgcgcctg
ctggactcgctcacctacttagagggtctcttggccttggtggtcttcgcgttgctcact
tttgtaggctctccctacggccgctactcgtcgcagcatcccggcctccaggtgccggcg
agacccgcctggttcctgcaggagctgccctcgatggcctggccactgtatgagtacgcc
cgccctgcagccgcgcgcctcggcagcctgcccaaccgtgtcctgctggccatgtttctg
acccactacgtgcaaaggactttggtttttcccgttctgatccgaggagggaaacccaca
cccctgttttcctttgctgctgcgatcctgttctgtaccttcaacggctacttgcagagc
aggtacttgagccagtttgcagtgtacgccgaagactgggtggcccatccctgtttcctg
attggttttgccttgtggctagcaggcatggtgataaatatccattcagaccacatcctg
aggaatctgagaaaacccggggaaacaggatacaagatccccaggggaggcttgtttgaa
tacgtctctgcagccaactacttcggggagattacggagtggtgtggctttgcactggcc
agtgggtccccccaggccggagtgtttgccctgttcacattcagcgcattgtttaccagg
gcgaagcagcatcaccagtggtaccatgagaagtttgaagattaccccaaatcaagaaaa
atgctaattccatttgtgctttag
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