Cricetulus griseus (Chinese hamster): 100766818 Help Entry 100766818         CDS       T02813                                  Symbol Insr Name (RefSeq) insulin receptor isoform X2   KO K04527   insulin receptor [EC:2.7.10.1] Organism cge  Cricetulus griseus (Chinese hamster) Pathway cge04010   MAPK signaling pathway cge04014   Ras signaling pathway cge04015   Rap1 signaling pathway cge04022   cGMP-PKG signaling pathway cge04066   HIF-1 signaling pathway cge04068   FoxO signaling pathway cge04072   Phospholipase D signaling pathway cge04150   mTOR signaling pathway cge04151   PI3K-Akt signaling pathway cge04152   AMPK signaling pathway cge04211   Longevity regulating pathway cge04213   Longevity regulating pathway - multiple species cge04520   Adherens junction cge04910   Insulin signaling pathway cge04913   Ovarian steroidogenesis cge04923   Regulation of lipolysis in adipocytes cge04930   Type II diabetes mellitus cge04931   Insulin resistance cge04932   Non-alcoholic fatty liver disease cge04960   Aldosterone-regulated sodium reabsorption cge05010   Alzheimer disease cge05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cge00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100766818 (Insr)    04014 Ras signaling pathway     100766818 (Insr)    04015 Rap1 signaling pathway     100766818 (Insr)    04066 HIF-1 signaling pathway     100766818 (Insr)    04068 FoxO signaling pathway     100766818 (Insr)    04072 Phospholipase D signaling pathway     100766818 (Insr)    04022 cGMP-PKG signaling pathway     100766818 (Insr)    04151 PI3K-Akt signaling pathway     100766818 (Insr)    04152 AMPK signaling pathway     100766818 (Insr)    04150 mTOR signaling pathway     100766818 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     100766818 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100766818 (Insr)    04923 Regulation of lipolysis in adipocytes     100766818 (Insr)    04913 Ovarian steroidogenesis     100766818 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100766818 (Insr)   09149 Aging    04211 Longevity regulating pathway     100766818 (Insr)    04213 Longevity regulating pathway - multiple species     100766818 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100766818 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100766818 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100766818 (Insr)    04932 Non-alcoholic fatty liver disease     100766818 (Insr)    04931 Insulin resistance     100766818 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cge01001]     100766818 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:cge04090]     100766818 (Insr) Enzymes [BR:cge01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      100766818 (Insr) Protein kinases [BR:cge01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    100766818 (Insr) CD molecules [BR:cge04090]  Proteins   100766818 (Insr) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  100766818 NCBI-ProteinID:  XP_027271565 UniProt:  A0A8C2MAM4 LinkDB All DBs Position 4:complement(88048799..88183186) Genome browser AA seq 1372 aa AA seqDB search MGSGRRRETTAAPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT FSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVY WERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDESSSECCSCPKTDSQ ILKELEESSFRKTFEDYLHNVVFVPRPSRKRRSLDEVGNVTATMPTLPDFPNISSTVVPT SQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKA DDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERG CRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSV VIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELG QGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLL GVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEIADGMAYL NAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKD GVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLEPPDNCPERLTDLMR MCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVPLD GSSHCHREEAGCREGGSSLSIKRTYDEHIPYTHMNGGKKNGRVLTLPRSNPS NT seq 4119 nt NT seq  +upstreamnt  +downstreamnt atgggctccgggagacgacgggagacgacggccgcgccgttgctggtggctgtggccgcg ttgctggtgggcgcagccggccacctgtaccccggagaggtatgccctggcatggacatc cggaacaacttgaccaggctgcatgagctggagaactgctctgttattgagggccatctg cagatcctcctgatgttcaaaaccaggcctgaagacttccgagacctcagtttccccaaa ctcatcatgatcacagactacctgcttcttttccgagtctatggcctggagagtctgaaa gacctcttccccaaccttacagtcatccgaggctcccgccttttcttcaactatgccctg gtcatctttgagatggttcacctgaaggagctggggctttacaacctcatgaacatcacc cggggctctgtccgcattgagaagaataacgagctctgctacctggccaccattgactgg tcccggatcctggattctgtggaggacaactacatcgtgctgaacaaagatgacaatgag gaatgtggggatgtctgtccaggcaccgccaagggcaagaccaattgccctgccaccgtc atcaatgggcagtttgtggaacggtgctggacacatagtcattgtcagaaagtttgcccg accatctgtaagtcacatggttgcacagctgaaggcctgtgctgccacaaggagtgccta ggcaactgttcggaaccggacgaccccactaagtgtgtggcctgccgcaacttctacctg gacggtcggtgtgtggagacctgcccgcccccctactaccacttccaggattggcgctgt gtgaacttcagcttctgtcaagaccttcactacaaatgcaggaactctaggaagcctggc tgtcaccaatacgtcattcacaacaacaagtgcatccctgagtgtccttctggctatacc atgaattccagcaacttgatgtgcaccccatgtctgggaccctgtcctaaggtctgccag atcctggatggcgagaagaccattgactctgtgacatctgcccaggagctccgaggctgc accgtgatcaatggcagcctcatcattaacatccgagggggcaacaacctggcagctgag ctggaggctaaccttggcctcattgaagaaatttcagggttcctaaaaatccggcgttcc tatgctctggtatctctttctttcttccggaagctccatctgattcgaggagagaccttg gaaatcgggaactactctttctacgccttggacaaccagaacctcaggcagctctgggac tggagcaaacacaacctcaccatcactcagggcaagctcttcttccactacaaccccaaa ctctgcttgtcagaaattcacaagatggaagaagtttctggaactaagggccgccaggag aggaacgacattgccctgaagaccaatggcgaccaggcatcctgtgaaaatgagttactt aaattttctttcattcggacatcttttgacaagatcttgctgaggtgggagccctactgg ccccctgatttccgagacctcctgggattcatgctcttctacaaagaggccccgtatcag aatgtgacagagtttgatgggcaggatgcttgtggctccaacagctggaccgtggtagat attgacccaccccaaaggtccaacgaccccaagtctcagaccccaagccaccctgggtgg ctaatgcggggtctcaagccctggactcaatatgccatctttgtcaagaccttggttacc ttctctgatgaacgccggacctacggagccaaaagtgacatcatctatgtgcagacagat gccactaacccttctgtccccttggaccccatatcagtttctaattcctcatctcagatt attttaaagtggaagcccccctccgaccccaatggcaacatcacacactacctggtctac tgggagaggcaggcggaggacagcgagctgtttgagttggattattgtctcaaagggctg aagctcccctcacggacctggtccccaccttttgaatcggatgattctcagaagcataat cagagcgagtatgacgagtcgtccagtgaatgctgctcatgccccaagactgactctcag atcctcaaggagctggaggaatcctcattcaggaagacctttgaggattacctgcataac gtggtgtttgtccccaggccatcccgaaaacgaagatcccttgacgaggtggggaatgtg acagccaccatgcccacacttccagattttcccaacatctcttccaccgttgtgcccacg agtcaggaagagcacaggccatttgagaaagtggtgaacaaggaatcacttgtcatctct ggcctgagacacttcactggctaccgcattgagctgcaggcctgcaaccaagactcccca gatgagaggtgcagtgtggctgcctacgtcagtgcccgaaccatgcctgaagctaaggca gatgacatcgttggccctgtgacccatgaaatctttgagaacaatgttgtacacttaatg tggcaagagccaaaggagcccaatggtctgattgtgctgtatgaagtgagctaccggcgc tatggtgatgaggagctgcacctctgtgtctcccggaagcattttgccctggagcggggc tgtagacttcgagggctctccccaggaaactacagtgttcgagtccgggctacctccctg gcaggcaatggctcctggacagaacccacctatttttatgtgaccgattatttagatgtc ccatcaaatattgccaaaattatcatcgggcctctcatctttgtcttcctcttcagtgtt gtgattggaagtatttatctgttcctgagaaagaggcagccggatggaccaatgggacca ttgtatgcatcttcaaaccctgagtacctcagtgccagtgatgtgtttccttcttctgtg tacgtgccggatgagtgggaggtgcctcgagagaagatcaccctcctacgagagctgggc cagggatcctttggtatggtgtatgaaggcaatgccaaggatatcatcaagggtgaggca gagacacgagttgcagtgaagactgtcaatgagtcagccagtctccgagaacgaattgag ttcctcaacgaggcatcggtcatgaagggattcacctgccatcatgtggtccgcctcctt ggggtagtgtccaagggccagccaacattggtggtgatggaattgatggctcatggagac ctgaagagtcacctccgttctctgcgaccggatgctgagaataacccgggccgtcctccc cctaccttgcaagaaatgattcagatgacagcagaaattgccgatggcatggcatacttg aatgccaagaagtttgtgcaccgggacctggcagctcgaaattgcatggttgctcatgac tttaccgtcaaaattggagactttggaatgacgagggatatctacgagacagattactat cggaaagggggcaagggcctgctgcctgtgcggtggatgtcacctgagtccttgaaggat ggagtctttaccgcttcttctgatatgtggtcctttggggtggtcctttgggaaatcacc agcctggctgagcaaccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatg gatggaggctatctggagccacctgataattgtcctgagagactcacggacctgatgcgc atgtgctggcagttcaaccccaagatgaggccaaccttcctggaaattgtcaacctgctc aaggatgacctccacccgagctttccagaagtttccttcttctacagcgaagagaacaag gctcctgagagcgaggagctggagatggagtttgaggacatggagaatgtccccttggat gggtcctctcactgtcatagggaagaggctgggtgccgggagggagggtcctctctgagc attaaacggacctatgacgaacacatcccgtacacccacatgaacgggggcaagaagaac gggcgcgtgctcaccctgcccaggtccaacccttcctaa

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