Cutibacterium granulosum: 4412665_00188
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Entry
4412665_00188 CDS
T05425
Symbol
cobA
Name
(GenBank) Uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cgrn
Cutibacterium granulosum
Pathway
cgrn00860
Porphyrin metabolism
cgrn01100
Metabolic pathways
cgrn01110
Biosynthesis of secondary metabolites
cgrn01120
Microbial metabolism in diverse environments
cgrn01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
cgrn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
4412665_00188 (cobA)
Enzymes [BR:
cgrn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
4412665_00188 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
4412665_00188 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Amidohydro_2
B12-binding
DUF6830
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
SNV28774
UniProt:
A0A239W4V3
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All DBs
Position
1:complement(202978..204645)
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AA seq
555 aa
AA seq
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MSETTSVIDASSGAESRPTATSQPRVQFVGTGPGDPSLLTIAAVRAINAAQVIVLTCPAH
RDLVESDVLALHDEVRIVPAGISAEEFDEQAEADLTAELVDSARRGLDVVRLVSGDPFLD
GDVAAEAAALAKADIDVDVMPGISPLTSVPEYAGVTLHGHDVQLIGPTAAKRDFQEEGHP
WARRGLIVARVTAGQVPLLVDHAIESGRDQDESAVLTRHGATTEQVSTTTTLAALPKVLP
ASRVESDEMVHVVIGRVAEGPSREELDWYESKPLFGWSVLIPRTRDHSAILPSRLQAYGA
HSFDVPTISMEPPRTPQQMDKAIRGLVEGRYEWVVFTSANAVRAVTEKLDAIGLDARAYS
GLRIAAIFDSTVDALTKQGVRPDLIPTGEQSTAALADVFPAFDDVLDPINRVFVPRADIA
TESLSAQLSDLGWEVEDIIGYRTVRAAPPPAETRDAIKTGKFDAVAFTSSTTVRNLVGIA
GKPHKYTVVAAIGARTAETCEEHGLHVDVVASEPTLPALADALADFAAHRRDDLIAKGSP
VVRPSQRRRRGRRSR
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
atgagcgagacgacctcggtgatcgacgcgtcttccggggcggaaagtcgtccgacggcc
acgtctcagccgcgcgtccagttcgtcggaactggtccgggagacccgtccctgttgacc
atcgcagcagtgcgggccatcaacgctgcgcaggtcatcgtgctcacctgcccggcacat
cgtgatctggtggagtccgacgtcctcgccctgcacgacgaggtgcgtatcgtccccgcc
gggatcagtgcggaggagttcgacgagcaggccgaagcagatctcaccgctgagctcgtc
gattccgcccggcgcggcctggacgtcgtgcgtctggtgagcggagaccccttcctcgac
ggggacgttgccgcggaggcagctgccctggccaaggccgacatcgacgtcgacgtcatg
ccgggcatctccccgctcacctcggtgcccgagtacgccggtgtcaccctgcacggccat
gacgttcagctcatcgggcccaccgctgccaaacgagactttcaggaggagggccatccc
tgggcacgacgcggcctcatcgtcgcccgtgtcactgctggacaagtcccgctgctcgtt
gaccatgccatcgagtccgggcgggaccaggatgagtcggctgtgctcactcgccacggt
gccaccaccgagcaggtctccacgacgaccaccttggctgcccttcccaaggtgcttccg
gccagtcgggtggagtccgatgagatggtgcacgtcgtcatcggacgagtggcagagggg
ccgtcacgtgaggagttggactggtacgagtccaagccactgttcggctggtcggtgctc
atcccacgtacccgcgaccactcggcgatcctgccctcccggctgcaggcctacggggcc
cactccttcgacgtgccgacgatctcgatggaaccgccgcgtaccccgcagcagatggac
aaggccattcgcggactggtcgagggacgttacgagtgggtcgtgttcacctcggcgaat
gcggtgcgggcagtcaccgagaagcttgacgccatcgggctggacgcgcgagcctactcg
gggttgcgcatcgccgcgatcttcgactccacggtggatgccttgaccaagcagggagtg
cgtcccgacctcatccccacgggggaacagtccacggccgccctggccgacgtcttccca
gccttcgacgacgttctggaccccatcaaccgggtcttcgtgccgcgcgccgacatcgcc
accgaatcactgtcggcccagctgtccgacctgggttgggaggtcgaggacatcatcggc
tatcgcaccgtgcgagctgccccaccaccagccgagacacgtgatgccatcaagaccggc
aaattcgacgccgtggccttcacctcctcgaccacggtgcgcaacctcgtcggtattgct
ggcaaaccccacaagtacaccgtggtggctgccattggggcgcgtactgccgagacctgt
gaggagcacgggctgcacgtcgacgtcgtcgcctccgagcccaccctgcctgccctggcc
gacgcgctggccgacttcgccgcccaccgacgggacgacctcatcgccaagggatcaccg
gtggttcgcccctcccagcgtcgtcgacgtggcaggcgtagtcgctga
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