Corynebacterium glutamicum K051: WA5_0414
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Entry
WA5_0414 CDS
T02508
Symbol
HemD
Name
(GenBank) uroporphyrinogen-III synthase/methylase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cgu
Corynebacterium glutamicum K051
Pathway
cgu00860
Porphyrin metabolism
cgu01100
Metabolic pathways
cgu01110
Biosynthesis of secondary metabolites
cgu01120
Microbial metabolism in diverse environments
cgu01240
Biosynthesis of cofactors
Module
cgu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cgu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
WA5_0414 (HemD)
Enzymes [BR:
cgu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
WA5_0414 (HemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
WA5_0414 (HemD)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
CCH23635
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Position
452637..454433
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AA seq
598 aa
AA seq
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MTIAHKPEMAETTGIETNQVSETIGVESLTHGNLRPVSSFEGQHEGQTEELLPGKVIFVG
AGPGNPDLLTVRAREVLGNAVRAITDEQVLSGVRAFVATEIPVPEDKLQAAEDEYERICI
EAKENGARRKPPRPAPPTAAEITEVSEATPAQIVELVQDALSYGGDVIRLVTGNPLSSDA
TLAEISAVSEAGLEFQVVPGMSLPATVPAFAGIALGSTYTETDVNGQNLDWDQLASAPQP
LVLQARVDDLSRIAQELKARNMSLETPVSVTANGTTRLQRTYDTTLGLLHKLDAELSGPL
VVTLGKGVDDRSKYSWWENRALYGWRVLVPRAREQAASMSARLSSHGAIPQEVPTISVEP
PRNPAQMERAIKGIVEGRYQWVVLTSVNAVKAVWEKITEFGLDSRSFAGVRIAAVGEKTA
AEIRALGITPELLPARTRQNAQGLVDVFPEYFEELDPVGRVLLPRADIATDVLVDGLTHL
GWEVEDVVAYRTVRAAPPSADIRDMIKTGGFDAVAFTSSSTVKNLVGIAGKPHPRTIVAC
IGPMTAATAEELGLRVDVMPEIAEVPELIDALAEHVADLRAKGELPPPRKKRRRRKAS
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
atgactatcgcccataagcccgagatggctgaaactaccgggatcgagaccaaccaggtt
tccgaaaccatcggggttgaatcgctcacgcacggaaacttacgtcctgtttcatctttt
gagggacagcatgagggacaaacggaagagttacttccaggcaaagtcatttttgttggg
gccggtcccggtaaccctgatcttcttacagttcgtgcccgtgaagttctgggcaacgcg
gttcgtgcgattactgatgaacaagtactaagcggcgttcgagcttttgtcgccactgaa
attcctgtgccggaagataagcttcaggctgcggaagatgagtacgagcgcatctgcatt
gaagcgaaggagaacggtgcacgccgtaagcctcctcgtccagcaccaccaaccgctgca
gagatcacggaagtttctgaggcgactccagctcagattgttgagcttgtgcaggatgct
ctttcttatggtggagatgttattcgtcttgtcaccggcaacccattgagcagcgatgcc
acactggctgagatctctgcagtttccgaggctggcctggagttccaggtggttccaggt
atgtctttgcctgcaacggttcctgcatttgcgggaattgcgttgggttctacctacacc
gaaactgatgtcaacggtcaaaacttggactgggatcagttggctagcgcacctcagcct
ttggtgctgcaggcccgcgtggatgacctttcccgtattgcacaggaactaaaggcccgc
aatatgtctttggaaactcctgtttctgtcaccgctaacggcaccacccgtttgcagcgc
acctatgacaccactttaggtctgttgcacaagcttgatgctgaactaagcggacctttg
gttgttaccttgggcaagggtgtggatgatcgctccaagtactcttggtgggaaaaccgc
gctctgtacggttggcgtgtgctggtgcctcgcgctcgggagcaagcggcatccatgtcc
gcacgtctgagcagccacggcgctatcccgcaggaagtccctaccatttctgtcgaacca
ccgcgcaacccagcgcaaatggaacgcgccatcaagggcatcgtcgaaggacgctaccag
tgggttgtcctcaccagcgtcaacgcagtgaaggcagtctgggagaaaatcaccgaattc
ggcctcgattcacgttccttcgcgggcgtccgcatcgccgcagtcggtgaaaaaaccgcc
gctgagatccgcgcgctcggcatcacgccggagcttctgcctgcacgtaccaggcaaaat
gcgcaagggcttgtcgacgtgttccccgaatatttcgaagaactcgatccagtcggccgt
gtcctcttgccgcgcgcagatatcgcaaccgacgtgcttgtcgacggcctgacccacctt
ggttgggaagtcgaagacgtggtggcttaccgcaccgtccgcgcagcaccaccaagcgct
gatatccgagatatgatcaagaccggcggatttgatgcagttgccttcacctcttcgtcg
accgtgaagaacctcgttggtatcgcgggtaaaccacacccacgcaccatcgtcgcgtgc
atcggacccatgactgcagcgaccgctgaagaactgggactgcgcgttgatgtcatgcca
gagatcgccgaagtaccagaactgatcgacgctcttgcggaacacgtggcggatctgcgc
gctaagggcgagctgccgccgccgaggaagaaacgcaggcgtcgaaaagcgtcttaa
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