Capra hircus (goat): 102168996 Help Entry 102168996         CDS       T02910                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism chx  Capra hircus (goat) Pathway chx04010   MAPK signaling pathway chx04014   Ras signaling pathway chx04015   Rap1 signaling pathway chx04022   cGMP-PKG signaling pathway chx04066   HIF-1 signaling pathway chx04068   FoxO signaling pathway chx04072   Phospholipase D signaling pathway chx04150   mTOR signaling pathway chx04151   PI3K-Akt signaling pathway chx04152   AMPK signaling pathway chx04211   Longevity regulating pathway chx04213   Longevity regulating pathway - multiple species chx04520   Adherens junction chx04910   Insulin signaling pathway chx04913   Ovarian steroidogenesis chx04923   Regulation of lipolysis in adipocytes chx04930   Type II diabetes mellitus chx04931   Insulin resistance chx04932   Non-alcoholic fatty liver disease chx04960   Aldosterone-regulated sodium reabsorption chx05010   Alzheimer disease chx05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102168996 (INSR)    04014 Ras signaling pathway     102168996 (INSR)    04015 Rap1 signaling pathway     102168996 (INSR)    04066 HIF-1 signaling pathway     102168996 (INSR)    04068 FoxO signaling pathway     102168996 (INSR)    04072 Phospholipase D signaling pathway     102168996 (INSR)    04022 cGMP-PKG signaling pathway     102168996 (INSR)    04151 PI3K-Akt signaling pathway     102168996 (INSR)    04152 AMPK signaling pathway     102168996 (INSR)    04150 mTOR signaling pathway     102168996 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     102168996 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102168996 (INSR)    04923 Regulation of lipolysis in adipocytes     102168996 (INSR)    04913 Ovarian steroidogenesis     102168996 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102168996 (INSR)   09149 Aging    04211 Longevity regulating pathway     102168996 (INSR)    04213 Longevity regulating pathway - multiple species     102168996 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102168996 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102168996 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102168996 (INSR)    04932 Non-alcoholic fatty liver disease     102168996 (INSR)    04931 Insulin resistance     102168996 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:chx01001]     102168996 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:chx04090]     102168996 (INSR) Enzymes [BR:chx01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102168996 (INSR) Protein kinases [BR:chx01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    102168996 (INSR) CD molecules [BR:chx04090]  Proteins   102168996 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  102168996 NCBI-ProteinID:  XP_017906623 EnsemblRapid:  ENSCHIG00000014171 LinkDB All DBs Position 7:complement(95922066..96070755) Genome browser AA seq 1382 aa AA seqDB search MGAGGGRGAAAVLLMVVVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL GNCSEPNDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCVPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWGKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPSRKRRALGDVGNVTAAVPTVLGF PNSSSTSTPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV SRRHYALERGCRLRGLLPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSICLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMESVPLDRSSHAQREEAGVRDGGSALGLKRNYDEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggcgggaggggggcggcagccgtgctgctgatggtggtcgtcgccgcg ctgctggtgggcgccgcgggccacctgtaccctggagaagtgtgccccggtatggatatc cggaataatctcacccggctgcatgagctggccaactgctcggtcattgaaggacatttg cagattctgttgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag gacttgttccccaacctcacggtcatccgaggctcgcgcctcttctttaattatgcactg gtcatctttgagatggttcacctgaaggagcttggcctctacagcctgatgaacatcacc cgggggtctgtccgcatcgagaagaacaatgaactctgctacctggccaccatcgactgg tctcgcatcctggattccgtggaggataattacatcgtgctaaacaaagacgacaatgag gagtgtggggacatttgtccaggcaccgccaagggcaagaccaactgccctgccactgtc atcaacgggcagtttgtggagcggtgctggacacacagccactgccagaaagtgtgtccg actatctgtaagtcacatggctgcacctctgagggtctctgctgccacagcgagtgcttg ggcaactgctcagagcccaacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gacggcaggtgcgtggagacctgcccgcccccttactaccacttccaagactggcgctgc gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcaaggc tgccaccagtatgtcattcacaacaacaagtgcgtccccgagtgcccctctggctacacg atgaattctagcaacttgatgtgtaccccttgcctgggcccctgtcccaaggtatgccac ctcctggaaggtgagaagaccatcgattcagtaacatctgcccaggagctccgaggctgc accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag ctagaggccaaccttggactcattgaggaaatttcaggatatctgaaaatccgccggtcc tatgccctggtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg gaaattgggaactactctttctacgccttggacaaccagaacctaaggcagctatgggac tggggcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa ctgtgcctgtcggaaattcacaagatggaggaagtttcaggaacgaaggggcgccaggag agaaatgacattgctttaaagaccaatggggaccaggcatcctgtgaaaatgaattactt aaattttcttacattcggacatcttatgacaagatcttgctgaaatgggagccgtattgg cctcctgacttccgagacctcctggggttcatgttgttctacaaagaggccccttaccag aatgtgacagaattcgatgggcaggatgcgtgcggctccaacagctggacagtggtggat attgacccacctacgaggtccaacgaccccaagtcacagaaccatcctgggtggctgatg cgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtcaccttttct gatgaacgccgtacatacggagccaagagtgacatcatctatgtccagacagatgccact aatccttccgtccccctggatcccatctcagtttctaattcctcgtcccagattattctg aagtggaagcctccctccgaccccaacggcaatatcacacactacttggtgttctgggag aggcaggcggaagacagtgagctgtatgaactggattattgcctcaaagggttgaagctg ccctcccggacctggtctccaccattcgagtcggaggggtctcagaagcacaaccagagt gagtatgaggagtctgctggcgaatgctgctcctgcccgaagaccgactctcagatcctc aaggagctggaggagtcctcgttcaggaaaacatttgaagattacctgcacaacgtggtt ttcatccccagaaaatcatcttcaggccctgttgccgaggacgctaggccttcgaggaaa cgcagagcccttggtgacgtggggaatgtgacagcagccgtgcccactgttctggggttc cccaatagctcctccaccagcacacccacgagctcagaggagcacagacccttcgagaaa gtggtgaacaaggagtcgctggtcatctccggcctgcgtcactttactgggtatcgcatc gagcttcaggcttgcaaccaagattcccccgaggagaggtgtagcgtggctgcctatgtc agcgccaggaccatgcctgaagccaaggcagatgatattgtcggccccgtgacccatgaa atcttcgagaacaacgtcgttcacttgatgtggcaggagcccaaggaacccaacggtctg attgtgctgtatgaagtgagttaccgacgatacggcgaggaggagctgcacctctgcgtc tcccgccggcattatgctctggagcgcggctgccggctgcgcgggctgctgcctgggaat tacagtgtgcgagttcgggccacctccctggcaggcaatgggtcttggacggaagccacc tacttctatgtgacagactatttagacgtgccatcaaatattgcaaaaatcatcatcggt cccctcatctttgtctttctcttcagtgttgtgattggaagtatttgtctattcctgaga aagaggcagccagatgggccactgggaccattgtatgcttcttcaaacccagagtacctc agtgccagcgatgtgttcccatgctctgtgtatgtgccggacgagtgggaggtgcctcga gagaagatcacgctcctgcgagaactgggtcaaggctccttcggcatggtgtacgagggc aacgccagggacattgtcaagggtgaggcggagacccgcgtggcagtgaagacggtcaac gagtcggccagcctgcgagagcggatcgagtttctcaacgaggcttcggtcatgaagggc ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctg gtggtgatggagttgatggctcacggagacctgaagagttacctccgttccctgcggcct gaggctgagaacaaccccggccgccctccccctaccctgcaagaaatgattcagatggcg gcagagatcgccgatgggatggcatacctgaacgctaagaagttcgtgcaccgggatctt gcagcccggaactgcatggttgcccacgactttaccgtcaaaattggagacttcggaatg acaagagacatctatgaaacggattactaccggaaagggggcaaaggtctgctccccgtg cggtggatggcacctgaatccctcaaggacggagtcttcaccacctcttcggacatgtgg tcttttggtgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggtcta tcaaatgagcaggtgctgaaatttgtcatggatggagggtacctggatcaacctgacaat tgtccagagagagtcaccgacctgatgcggatgtgctggcagttcaaccccaagatgcgt ccgaccttcctggagatcgtggacctgctcaaggatgacctgcaccccagctttcccgaa gtgtccttcttccacagcgaggagaacaaggcacccgagagcgaggagctggaaatggag tttgaggacatggagagcgtgcccctggaccggtcctcgcacgcgcagagagaggaggcc ggggtccgggacggagggtcggcgctggggctaaagcgaaactatgacgagcacatcccc tacacccacatgaacgggggcaagaaaaacggacggattctgactttgccccggtcaaat ccttcctaa

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