Callithrix jacchus (white-tufted-ear marmoset): 100405019
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Entry
100405019 CDS
T03264
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00220
Arginine biosynthesis
cjc00330
Arginine and proline metabolism
cjc01100
Metabolic pathways
cjc04020
Calcium signaling pathway
cjc04022
cGMP-PKG signaling pathway
cjc04066
HIF-1 signaling pathway
cjc04071
Sphingolipid signaling pathway
cjc04151
PI3K-Akt signaling pathway
cjc04370
VEGF signaling pathway
cjc04371
Apelin signaling pathway
cjc04611
Platelet activation
cjc04915
Estrogen signaling pathway
cjc04921
Oxytocin signaling pathway
cjc04926
Relaxin signaling pathway
cjc04931
Insulin resistance
cjc04933
AGE-RAGE signaling pathway in diabetic complications
cjc05415
Diabetic cardiomyopathy
cjc05417
Lipid and atherosclerosis
cjc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100405019 (NOS3)
00330 Arginine and proline metabolism
100405019 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100405019 (NOS3)
04371 Apelin signaling pathway
100405019 (NOS3)
04066 HIF-1 signaling pathway
100405019 (NOS3)
04020 Calcium signaling pathway
100405019 (NOS3)
04071 Sphingolipid signaling pathway
100405019 (NOS3)
04022 cGMP-PKG signaling pathway
100405019 (NOS3)
04151 PI3K-Akt signaling pathway
100405019 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100405019 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100405019 (NOS3)
04921 Oxytocin signaling pathway
100405019 (NOS3)
04926 Relaxin signaling pathway
100405019 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100405019 (NOS3)
05418 Fluid shear stress and atherosclerosis
100405019 (NOS3)
05415 Diabetic cardiomyopathy
100405019 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100405019 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100405019 (NOS3)
Enzymes [BR:
cjc01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100405019 (NOS3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DUF6285
Motif
Other DBs
NCBI-GeneID:
100405019
NCBI-ProteinID:
XP_035110263
LinkDB
All DBs
Position
8:complement(94509190..94531330)
Genome browser
AA seq
1203 aa
AA seq
DB search
MGNLKSVAQESGPPCGLGLGLGFGLCGKQSPATPAPEPSQAPASPPPPAPEHSPPSSPLT
QPPEGPRFPRVKNWEVGSIAYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPTAP
EQLLSQAQAFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGSGRFDVLPLLLQAPDEPP
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMARRVKATVLYGSETGRAQGYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
RDVFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSIHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVHDAQQRGVFGRVLTAFSRE
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDLELE
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPTSDT
NGP
NT seq
3612 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtggcccaagagtctgggccaccctgcggcctggggctgggg
ctgggcttcgggctgtgtggcaagcagagcccagccaccccggcccctgagcccagccaa
gccccagcatcccctcccccaccagcgccagaacacagccccccgagctccccgctaacc
cagccaccggaagggcccaggttccctcgagtgaagaactgggaggtggggagcatcgcc
tatgacaccctcagcgcccaggcacagcaggatgggccctgcaccccaagacgctgcctg
ggctccctggtatttccgaggaaactgcagggccggccctcccccggccccacagcacct
gagcagctgctgagtcaggcccaggccttcatcaaccagtactacagctccatcaagagg
agtggctcccaggcccacgagcagcggcttcaagaggtggaagccgaagtggcagccaca
ggcacctaccagcttagggagagcgagctggtgttcggagccaagcaggcctggcgcaat
gctcccagatgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcgcgggac
tgcaggtctgcccaggagatgttcacctacatctgcaaccacatcaagtatgccaccaac
cggggcaaccttcgctcagccatcacagtgttccctcagcgctgccctggccgcggagac
tttcgaatctggaacagccagctggtgcgctacgcaggctaccggcagcaggacggctcc
gtgcggggggacccggccaacgtggagatcactgagctctgcatccagcacggctggacc
ccaggaagtggccgcttcgacgtgctgccgctgctgctgcaggccccagacgagccccca
gaactcttccttctgcccccagagctggtccttgaggtgcccctggagcaccccacgctg
gagtggtttgcagccctgggcctgcgctggtatgccctcccggcggtctccaacatgctg
ctggaaattgggggtctggagttccctgcagcccccttcagtggctggtacatgagcact
gagattggcaccaggaacctgtgtgacccccaccgctacaacatcctggaggacgtggct
gtctgcatggacctggatacccggacgacctcgtccctgtggaaagacaaggcggcggtg
gaaatcaacgtggctgtgctgcacagttaccagctggccaaagtgaccatcgtggaccac
cacgctgccacagcttccttcatgaaacacctggagaatgagcagaaggccagggggggc
tgccctgcagactgggcctggatcgtgccccccatctcaggcagcctcactcctgtcttc
catcaggagatggtcaactatttcctgtcccctgccttccgctaccagccagacccctgg
aaggggagtgcagccaagggcaccggcatcaccaggaagaagacctttaaggaagtggcc
aacgccgtgaagatctccgcctcgctcatgggcaccgtgatggctaggcgggtgaaggca
acagtcctgtacggctctgagaccggccgggcccagggctacgcacagcagttggggaga
ctcttccggaaggcttttgacccccgggtcctgtgtatggatgagtatgacgtggtgtcc
ctggaacacgagacactggtgctggtggtaaccagcacatttgggaatggcgatcccccg
gagaatggagagagctttgcagctgccctgatggagatgtccggcccttacaacagctcc
ccgaggccagagcagcacaagagttacaagatccgcttcaacagcgtctcctgctcagac
ccactggtgtcctcgtggcggcggaagaggaaggagtccagtaacacagacagtgcaggg
gccctgggcaccctcaggttctgtgtgttcgggctgggctcccgggcgtacccccacttc
tgcgcctttgctcgagcggtagacacgcggctggaggaactgggaggggagcggctgctg
cagctgggccagggcgacgagctgtgtggccaggaggaagccttccgaggctgggcccag
gctgccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaaagctgccgcc
cgagatgtcttcagccccaaacgcagctggaagcgccagaggtaccggctgagcacccag
gccgagggcctgcagctgctgccaggtctgatccacgtgcacaggcggaagatgttccag
gctacaatcctttcagtggaaaacctgcaaagcagcaagtccacgcgggccaccatcctg
gtgcgcctggacaccggaggccaggaggggctgcagtaccagccaggggaccacataggc
atctgcccacccaaccggcctggccttgtggaggcgctgctgagccgcgtggaggacccg
ccagcacccactgagcccgtggcagtagagcagctggagaagggcagccctggtggccct
ccccccggctgggtgcgggacccccggctgcccccgtgcacactgcgccaggctctcacc
ttcttcctggacattacctccccacccagtcctcagctcttgcggctgctcagcactctg
gcagaagagcccagggaacagcaggagctggaggccctcagccaggatccccggcgctac
gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccgtca
gtggcactgcctgccccactgctcctcacccagctgcctctgctgcagccccgctactac
tcagtcagctcagcacctagcatccacccaggagagatccacctcacagtagctgtgctg
gcatacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggcta
agccaactcaagcctggagaccctgtgccctgcttcatccggggggctccctccttccgg
ctgccgcccgatcccagcctgccctgcatcctggtgggcccaggcactggcattgccccc
ttccggggattctggcaggagcggctgcatgacatcgagagcaaagggctgcagcctgcc
cccatgactttggtgttcggctgccggtgctcccaacttgaccatctctaccgcgacgag
gtgcacgacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaa
cccgacaatcccaagacctacgtgcaggacatcctaaggacggagctggctgcggaggtg
caccgcgttctgtgccttgagcggggccacatgtttgtctgcggcgatgtcaccatggca
accaacgtcctgcagaccgtgcagcgcatcctggcgaccgagggcgacttggagctggaa
gaggccggcgacgtcattggcgtgctgcgggatcagcaacgctaccacgaagacattttt
gggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagtttttccttg
caggagcggcagttgcggggcgcagtaccctgggcgttcgacccgcccacctcagacacc
aatggcccttga
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