KEGG   Clostridium sp. SY8519: CXIVA_15060
Entry
CXIVA_15060       CDS       T01565                                 
Symbol
CysG
Name
(GenBank) uroporphyrinogen-III methylase
  KO
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
cls  Clostridium sp. SY8519
Pathway
cls00860  Porphyrin metabolism
cls01100  Metabolic pathways
cls01110  Biosynthesis of secondary metabolites
cls01120  Microbial metabolism in diverse environments
cls01240  Biosynthesis of cofactors
Module
cls_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:cls00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    CXIVA_15060 (CysG)
Enzymes [BR:cls01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     CXIVA_15060 (CysG)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     CXIVA_15060 (CysG)
SSDB
Motif
Pfam: Porphobil_deam HEM4 TP_methylase Porphobil_deamC SH3DP
Other DBs
NCBI-ProteinID: BAK47472
UniProt: F7V3Z3
LinkDB
Position
1629505..1631901
AA seq 798 aa
MATRSSRLALAQAEEVRHALEQLGYTVELKTVTTHGDRDRKSPLTQIGGSGLFVSEIEQM
LLRGEADLAVHSGKDLPYRLMEGMVIGGVPAAEDGRDCLVSRKGEELPEHPRIGTGSPRR
VAQGRALFPGAEFAEIRGNVDTRLRKLSEGSYDAVILARAGLNRLKADLSAYDCRVLEPS
EMLPAPCQGILAVECRAEDEALCAALRKLSDPRSWKRFTAERCLFQMLQADCSMPVGVRA
EVSAAAGSSEKGNAWESMKSGERMEAGEASDAGQEQLTLQGFFGGRRAVRTGRYAEYPRL
CREVADELLRQTGSVCLVGAGCGRDLITVKGLRALRQAEVAVYDDLADGGLLMETPADCR
WIYVGKRSGRHSWKQAEINQLLVEEAGKGYRVVRLKGGDSFVFGRGGEEILALQEAGIPY
EVIPGITSSVAVPEHGGIPVTHRQTAQSFTVITGHSASDREENYSALAQLDGTLVFLMGL
GRLPQITGELMRQGKPADTPAAVISQGFEAGERRYTATLGTIAEKASGARTPAVLVIGDT
AGFHMEGTVRRPLQGVGVTVTGTAAFAGKLEARLAELGADTELLPCLRILPAGERVPEDL
TAYQWIVFTSSSGVEIFFDQLRRRNTDIRRLSAVKFACIGSGTAGSLRKNGILADFVPSA
YTAECLGRELPEVLAAGERVLILRAAHGSPDLNTGLDRAGTAYADIPIYRTCREPRILKG
SRADRDYIVFASASGVRAYFENYGSIGTACPVCIGESTRKALLPYNTGRCLVPRVHTAEG
LVEVIQRDMEADRRKQTP
NT seq 2397 nt   +upstreamnt  +downstreamnt
ttggccaccagaagcagccgtctggccctggcgcaggcagaagaggtcagacatgccctg
gaacagcttggatacacggtggagcttaagaccgtcaccacacacggagaccgggaccgg
aagagtccgctgacacagatcggcggcagcggactcttcgtttcggagattgagcagatg
ctcctgcgcggggaggcggacctggcggtgcattccggcaaagacctgccttaccggctg
atggaagggatggtgatcggcggcgtgccggctgccgaagacggcagagactgcctggtt
tccagaaagggcgaagaactgccggaacatccgcggatcggcaccgggagcccgcggcgt
gtggcccagggacgggcgcttttcccaggggctgaatttgcggagattcggggcaacgtg
gacaccaggctcaggaaactgtctgaaggaagctatgatgcggtgattctggcccgggcg
ggactgaaccggctgaaagcggatctgtcggcctatgactgccgggtgctggaaccgtcg
gaaatgctgccggcgccctgccagggaatcctggcagtggaatgccgggcagaggatgaa
gcgctttgcgcagcgctgcggaaactgtcggatccgcggagctggaagcgctttaccgcg
gagcgctgtctgtttcagatgctgcaggcggattgttccatgcctgtgggcgtgcgggcc
gaggtgtctgccgccgcgggatcttcggaaaaggggaacgcctgggaaagtatgaaatcc
ggggaaaggatggaagccggggaagcgtcagatgccggacaggaacagctgaccctgcag
ggatttttcggcggacgccgtgcggtgcggaccggacggtacgcggagtatccgcgtctt
tgcagggaagtggcggatgaactgctgcggcagaccggctcggtctgtctggtgggcgcc
ggctgcggcagggacctgatcaccgtaaaaggcctgcgtgccctccgccaggcagaagtg
gcggtctatgatgatctggcggacggggggcttctgatggagacccctgcggactgccgg
tggatctatgtgggcaaacggagcggcagacacagctggaaacaggcagagatcaatcag
ctgctggtggaggaagccgggaagggataccgggtggtccggctcaaaggaggagacagc
tttgtcttcggccggggcggcgaagaaatcctggccctgcaggaagcggggattccctat
gaagtgataccgggcatcacatcttctgtggcggtgccggagcatggggggattccggtg
acccatcgtcagacggcgcagtcctttaccgtgataaccgggcattccgcctcggaccgg
gaagaaaattacagcgccctggcgcagctggacggtacgctggtgtttctgatgggactg
ggacgcctgccgcagatcaccggggaactgatgcgtcaggggaaaccggcggatacgccg
gctgcggtgatttctcagggatttgaagcaggggaacgccgctataccgccaccctgggc
accattgcggaaaaggcgtccggtgcccggacaccggcggtgcttgtgatcggggatacg
gcaggatttcacatggaaggaacggtccggcggccgctgcagggagtcggggtcacggta
acagggactgcggcgtttgccggaaaactggaagccaggcttgcggagcttggagcagat
accgagctgctgccctgcctgcggatccttccggcgggggaacgcgtgccggaggatctg
accgcttatcaatggattgtattcaccagcagcagcggggtggagattttctttgatcag
ctgcgccggcgaaatacagatatccgcaggctttccgcggtcaaatttgcctgcatcggc
agcgggacagccggaagcctgcggaaaaacggcatcctggcggattttgtgccttccgcg
tacacggcggaatgcctcggccgggagctgccggaggtgctggctgccggggaacgggta
ctgattctgcgggcagcgcacggctcgccggatctgaataccggactggaccgggccggc
actgcttacgcggatattccgatataccggacctgcagggagccgcggattctgaaagga
agcagggcagaccgggattatatcgtatttgccagcgcctccggggtgcgggcttatttt
gaaaactatggatctatcggcactgcctgtccggtgtgcatcggagaaagcaccagaaag
gcacttctgccgtataataccggcaggtgtctggtgccgcgggtgcatacggcagagggg
ctggtggaagtaatacagagggatatggaagcagacaggaggaaacagacaccatga

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