Canis lupus dingo (dingo): 112647170 Help Entry 112647170         CDS       T08371                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism clud  Canis lupus dingo (dingo) Pathway clud01521   EGFR tyrosine kinase inhibitor resistance clud04151   PI3K-Akt signaling pathway clud04217   Necroptosis clud04380   Osteoclast differentiation clud04550   Signaling pathways regulating pluripotency of stem cells clud04620   Toll-like receptor signaling pathway clud04621   NOD-like receptor signaling pathway clud04630   JAK-STAT signaling pathway clud04658   Th1 and Th2 cell differentiation clud04659   Th17 cell differentiation clud05140   Leishmaniasis clud05145   Toxoplasmosis clud05152   Tuberculosis clud05160   Hepatitis C clud05161   Hepatitis B clud05162   Measles clud05163   Human cytomegalovirus infection clud05164   Influenza A clud05165   Human papillomavirus infection clud05166   Human T-cell leukemia virus 1 infection clud05167   Kaposi sarcoma-associated herpesvirus infection clud05168   Herpes simplex virus 1 infection clud05169   Epstein-Barr virus infection clud05171   Coronavirus disease - COVID-19 clud05200   Pathways in cancer clud05203   Viral carcinogenesis clud05212   Pancreatic cancer clud05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:clud00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     112647170 (JAK1)    04151 PI3K-Akt signaling pathway     112647170 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     112647170 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     112647170 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     112647170 (JAK1)    04621 NOD-like receptor signaling pathway     112647170 (JAK1)    04658 Th1 and Th2 cell differentiation     112647170 (JAK1)    04659 Th17 cell differentiation     112647170 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     112647170 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112647170 (JAK1)    05203 Viral carcinogenesis     112647170 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     112647170 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     112647170 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112647170 (JAK1)    05161 Hepatitis B     112647170 (JAK1)    05160 Hepatitis C     112647170 (JAK1)    05171 Coronavirus disease - COVID-19     112647170 (JAK1)    05164 Influenza A     112647170 (JAK1)    05162 Measles     112647170 (JAK1)    05168 Herpes simplex virus 1 infection     112647170 (JAK1)    05163 Human cytomegalovirus infection     112647170 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     112647170 (JAK1)    05169 Epstein-Barr virus infection     112647170 (JAK1)    05165 Human papillomavirus infection     112647170 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     112647170 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     112647170 (JAK1)    05140 Leishmaniasis     112647170 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     112647170 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:clud01001]     112647170 (JAK1) Enzymes [BR:clud01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      112647170 (JAK1) Protein kinases [BR:clud01001]  Non-receptor tyrosine kinases   JAK family [OT]    112647170 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  112647170 NCBI-ProteinID:  XP_048966299 Ensembl:  ENSCAFG00020018270 LinkDB All DBs Position 5:45440294..45520146 Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHPNDSGNILYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEMLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRRSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPHCPEEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgaggtgaatctggaggcccctgaaccaggggtggaagtgctcttc tatctttctgatagagagcccctccggctgggcagcggagagtacacagcagaggagcta tgcatcagggccgcgcaggaatgctgtatctctccactttgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccgttgatgacaag acatcgctccggctccactaccggatgaggttctatttcaccaactggcatgggactaat gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa aaaaaagttccagatgctacccctcttcttgatgccagttctttggagtatctctttgct cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagactgagcag gatgggcacgatattgagaatgagtgtctgggaatggctgtcctggccatctcccactat gccatgatgaagaagatgcagttgccagaacttcccaaggacatcagctataagcgatat attccagagaccttgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctgaaggaatttaataacaagactatttgtgacagtagt gtatctactcatgacctaaaggtgaaatatctggctaccttggaaactttgacaaagcat tatggcgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat tggtttcatccgaacgacagtggaaacattctctactatgaagtgatggtaactggaaat cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa ctgaaacggaaaaaactggaaaataaacacaagaaggacgaggagaaaaacaaaatccgg gaagagtggaacaatttttcttacttccctgaaatcacacacattgtaataaaggagtct gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcatcccatgag gaggccttgtcctttgtgtccctggtagacggctacttccggctcacagcagatgcccat cattacctctgcactgatgtggctcccccattgatcgtccacaacatacagaatggttgt cacggtccaatctgcacagaatacgccatcaataagttgcggcaagaaggaagcgaggag gggatgtatgtgctgaggtggagctgtaccgacttcgacaatattctcatgactgtcacc tgctttgaaaaatctgagatgctgggtggccagaaacagttcaagaattttcagattgag gtgcagaagggccgctatagcctgcacggctcagaccgcagcttccccagcctaggggac ctgatgagccacctcaagaagcagatcctgcgtacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagagatctccaatctgctggtggctactaagaaagcc caagagtggcagccagtctaccccatgagccagctgagttttgaccggatcctcaagaag gatattgtgcaaggagagcaccttgggagaggcacacggacacacatctactccggtact ctggtggattataaggacgatgaaggaacctctgaagaaaagagaataaaagtcatcctc aaagtcttagaccccagccacagggacatttctctggctttctttgaggcagccagcatg atgaggcaggtctcccacaaacacatcgtgtacctctacggcgtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggagggggggcctctagatctcttcatgcaccgg agaagtgatgtcctcaccacaccatggaagttcaaagttgccaaacagctggccagcgcc ctgagttacttggaggataaagacctagttcatggaaatgtgtgcactaaaaaccttctc ctggcccgtgagggcattgacagcgagtgcggcccgttcatcaagctcagtgaccctggc atccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccatggattgctcct gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acattgtgggaaatctgctacaatggcgagatccctctgaaagacaagaccctgattgag aaagagagattctacgaaagccggtgccggccagtgacaccatcttgtaaggagctggct gaccttatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatc atgagagacatcaataaactggaagagcagaatccagacattgtttccgaaagaaagcca gcaaccgaagtggatcccacacattttgaaaagcggttcttgaagaggatccgtgacctg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggataatact ggagagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgat ctgaagaaggaaatcgaaattctaaggaacctttatcatgagaacattgtgaagtacaaa ggcatctgtacagaagacggaggaaatggtattaagctcatcatggaatttctgccttca ggaagtcttaaggaatatcttccaaagaataagaacaaaattaacctcaaacaacagtta aaatatgctgttcagatttgtaaggggatggactatttaggttctcggcaatatgttcac cgggacttagcagcaaggaatgtccttgttgagagtgaacaccaagtgaaaattggagac tttggtttgaccaaagcaattgaaactgacaaggagtactacacagtcaaggatgatcgg gacagccctgtgttttggtatgctcctgaatgtttaattcaatgtaaattttatatcgcc tctgatgtctggtcgtttggagtgaccctgcatgagttgcttacttattgtgactcagat tccagccccatggcgttgtttctgaaaatgataggcccaactcatggccagatgacagta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctcactgtcca gaagaggtttatcaacttatgagaaaatgctgggaattccagccatctaatcggacaact tttcagaaccttattgaaggatttgaagcacttttaaaataa

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