Canis lupus dingo (dingo): 112653806
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Entry
112653806 CDS
T08371
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud00010
Glycolysis / Gluconeogenesis
clud00020
Citrate cycle (TCA cycle)
clud00620
Pyruvate metabolism
clud00785
Lipoic acid metabolism
clud01100
Metabolic pathways
clud01200
Carbon metabolism
clud01210
2-Oxocarboxylic acid metabolism
clud04066
HIF-1 signaling pathway
clud04922
Glucagon signaling pathway
clud05230
Central carbon metabolism in cancer
clud05415
Diabetic cardiomyopathy
Module
clud_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
112653806 (PDHA1)
00020 Citrate cycle (TCA cycle)
112653806 (PDHA1)
00620 Pyruvate metabolism
112653806 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112653806 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
112653806 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
112653806 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112653806 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112653806 (PDHA1)
Enzymes [BR:
clud01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
112653806 (PDHA1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
112653806
NCBI-ProteinID:
XP_025293846
Ensembl:
ENSCAFG00020004526
LinkDB
All DBs
Position
X:15295233..15312949
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVSQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtctcccgcgtgttgtcgggcgtctcccagaagccggca
agcagagtgttggtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgcgatcttcaccggctagaagagggccctcccgtcaccacagtgctcaccagggaggat
gggctcaggtactataggatgatgcagactgttcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggctggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttactcgtggcctttctgtcagagaaattctcgcagagcttacagga
cgaagaggaggttgtgctaaaggaaaaggtggatcgatgcatatgtatgccaagaacttc
tatgggggtaatggcattgttggagctcaggtgcccttgggagcaggaattgctttggcc
tgtaagtataatggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaaattgccgtgtatcttc
atctgtgagaataaccgctacggaatgggaacgtctgttgagagagcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgcgggtagatggaatggatatcttg
tgtgtccgggaggcaacaaggtttgcagccgcctactgtagatctggaaaggggcccata
ttgatggagctacagacttaccgttaccatggacacagcatgagcgaccctggtgtcagt
taccgtacacgagaggagattcaggaagtaagaagtaagagcgaccctatcatgcttctc
aaggatagaatggtgaacagcaacctggccagtgtcgaggaactaaaggaaattgatgtt
gaagtgaggaaggaaattgaggatgctgcccagtttgccactgctgatccggaaccgcct
ttggaagaactaggctatcacatttacagcagcgatccgccttttgaagttcggggtgca
aatcagtggatcaagtttaagtctatcagttaa
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