Cryptococcus neoformans var. neoformans JEC21: CNC04040
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Entry
CNC04040 CDS
T00243
Name
(RefSeq) folic acid and derivative biosynthesis-related protein, putative
KO
K13939
dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:
4.1.2.25
2.7.6.3
2.5.1.15
]
Organism
cne
Cryptococcus neoformans var. neoformans JEC21
Pathway
cne00790
Folate biosynthesis
cne01100
Metabolic pathways
cne01240
Biosynthesis of cofactors
Module
cne_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
cne00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CNC04040
Enzymes [BR:
cne01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.15 dihydropteroate synthase
CNC04040
2.7 Transferring phosphorus-containing groups
2.7.6 Diphosphotransferases
2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
CNC04040
4. Lyases
4.1 Carbon-carbon lyases
4.1.2 Aldehyde-lyases
4.1.2.25 dihydroneopterin aldolase
CNC04040
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Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
HPPK
FolB
Motif
Other DBs
NCBI-GeneID:
3256788
NCBI-ProteinID:
XP_570005
UniProt:
Q5KK71
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Position
3:complement(join(1249973..1250969,1251028..1251272,1251324..1251731,1251795..1252352))
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AA seq
735 aa
AA seq
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MPPDTITISSLTLHLPHGLGPSAFHLTPSPPCPALLSLTIHLVPNSVSATAAGDSMAGLG
VNYSSVSKAVYALANDAEKVWSGPWELMRAVSAIPLGFDDVQSVDIRLGLPKALLHALEA
VYKASYAKNGEETGRSCTIRDLKVVCIVGLHEHERKEKQRLELDVKVRGGDWNVWGHKGF
ADEIYDFVSNSAYGTIESLNHELGQHLLKSRYLGDPTQSHLEITIRKPSAIPFATPSITI
HRSQADYAPSLPSGTACNAPREALERVFVAVGSNIGDRVANITRAVSLLEEAGCKLLGTS
RLYESEPMYVEDQDRFINGVIELATPLEPLEVLRLLKHIEKAVGRTKTFTNGPRVIDLDL
VFYGHRVVKIGNETDEEDEHGIKWLECPHKRLREREFVLRPLADIDPEFTHPALRRSVGQ
LLASLPTTFPPSLSPIIPLHSHSSPLRLSIPASPYIMAIFNTTPDSFSDGDPARTNVEYA
LAACEKLLKGPEPPAILDIGGMSTRPGSEPCSEEDELSRVIPLVKAIRSSSNPIVASIPI
SVDTYRPSVAKAAVEAGASIINDVRGGQEPGMLRVMAEADVPVVLMHSRGDSKTMIAADV
QDYDSHGGVIKGVIQEMRVLVEQALKSGVKRWNIILDPGLGFAKSSSQSLTLLKHLPDLV
LPGTGLERLPMLVGASRKGFVGQTIKRAVPKERSFGDAAVSGWCASSGVVDILRVHEPRE
MAEVVKMACAIRDAE
NT seq
2208 nt
NT seq
+upstream
nt +downstream
nt
atgcccccggatacgataaccatctcatctctcacacttcacctgccacacggcctaggt
ccgtccgcctttcacctcaccccgtcccctccctgtccagcccttctctccctcacaatt
cacctcgtccccaactctgtctctgccaccgccgcaggggactccatggcaggccttgga
gtaaactactcttcagtatccaaagcggtatatgcccttgcgaatgatgccgaaaaggta
tggagcggaccatgggagctgatgcgcgctgtcagtgccatcccgctagggtttgatgat
gtccagagcgtagatatccgtctaggccttccaaaggcactgctacatgctctagaagct
gtgtacaaggcgtcctatgccaaaaatggcgaagaaaccggcaggagctgtacaatccgg
gacttgaaggtagtgtgtattgtgggactacatgagcatgagagaaaagagaagcagagg
ctggagttggatgtcaaggtcagaggaggcgactggaatgtttggggacacaagggattt
gcagatgaaatatacgactttgtgagcaactcggcttacggaactatcgaatcgctgaac
cacgaactgggacaacatcttctgaagagtcgctatctgggggatcccactcaatctcat
ctagaaattacaatcaggaaaccatcggcaatacctttcgctactccaagcatcacgatt
catcgctcacaggccgactatgcgccaagtctaccatctggcaccgcttgcaatgcgcca
cgcgaagcccttgagagggtattcgtggctgtcggctccaatatcggtgacagagtagcc
aacatcacaagagccgtaagccttttagaggaggctggatgtaaattgctaggtactagt
agactgtacgagagtgaaccgatgtatgtggaagatcaggaccggttcatcaatggtgtc
attgagctagctacaccacttgagcccttggaagttcttcgattgctcaaacacatagag
aaagctgtcgggcgtacaaagacattcacgaatggtcctcgagtcatcgatctagatttg
gtcttttatggtcaccgagtggttaaaattggcaacgaaactgatgaggaagatgaacat
gggatcaaatggttagaatgccctcacaaaagactacgtgagcgagagtttgttttgagg
ccgctggccgacattgatccagagttcacgcaccctgcgcttcgccgatccgtcggccag
cttctcgccagtcttccaaccacgtttccgccatctctttcacctataatccccttacac
tctcactcttctccccttaggctttccatccctgcctccccatacatcatggccatcttc
aatacaacaccagattcattttctgatggcgatcccgccaggacgaatgtcgaatatgcg
ctcgccgcttgcgaaaagctgttaaaaggacctgagcctccggctattctcgacattggg
ggaatgtccacgcgcccaggttctgaaccctgttcagaggaagacgagctcagtcgcgtt
atcccacttgtcaaagccatccgatcatcaagtaatcccatcgttgcatcgattccgata
tcagttgacacttatcgaccgtcagttgccaaggctgctgttgaagctggtgcatccatc
attaacgacgtccgtggcggacaagagccaggaatgttgcgggtcatggcagaagcagac
gttcctgttgttctgatgcattctaggggtgattcaaaaaccatgattgcagcggatgtc
caggattatgatagccacggaggtgtcatcaagggtgtgatacaggagatgagggtcttg
gtagagcaggccttgaagtctggcgtcaaacgatggaatatcatcctcgatcctggcttg
ggctttgccaagtcttcctctcaaagcttaacattgctcaaacacctgcctgatcttgtc
cttccagggaccggactggagagacttccgatgttagtaggtgccagcagaaagggattt
gtaggtcagaccataaaacgggctgtaccaaaagagaggagttttggagatgcggctgtc
agcggttggtgcgcttccagtggagttgtggacatcttaagagtccatgagcctagagag
atggctgaagttgtaaaaatggcatgtgctattagggatgcagagtag
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