Cavia porcellus (domestic guinea pig): 100713595
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Entry
100713595 CDS
T07777
Symbol
Dot1l
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00310
Lysine degradation
cpoc01100
Metabolic pathways
cpoc05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100713595 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
100713595 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cpoc03036
]
100713595 (Dot1l)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
100713595 (Dot1l)
Chromosome and associated proteins [BR:
cpoc03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100713595 (Dot1l)
HMT complexes
Dot1-containing complex
100713595 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
100713595
NCBI-ProteinID:
XP_005008771
Ensembl:
ENSCPOG00000019953
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAAVPAEAPMDSGAEEEKTGVTTVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNAA
NPERKPKKNQTALDLLHSQTVSQTASSSPQDAYRSPHSPFYQLPPSVPRHGPNPLLVAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKERNAQLLGTVQQLFGHCQTQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNRALRGQSLQLL
RARCEELKLDWSTLSLEKLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDTLPVPLRGKSTLGRELDTEAAGRLHLELDCAKFSLPPFSSASPELSMNGHAAG
YELCSVLSRPSSKQNTPQYLASPLEQEVVPCTPSHTGRPRLEQLSGLALPDYTRLSPAKV
VLRRHLSQDHGGSAKVATNEPHPRAEHPKESSLPYQSPGLPPSMKLSPQDPRPPSPGAAP
QAGEKGSEKGGKERMYGSHGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERVRS
TPSPGPQPRDAASALDKQIGANAHSAGSNASGSRSLALASAGFSYAGSVAISGALAGSPA
PPAPGVEPATFDEPSGSLFATVGSRSATPQHPPLLAQPRNSGPASPAHQLSASPRLIGAT
QGLLPDMGKGDLPTDLGFSDPESDAKRRIVFTISAGAGSAKQSPSTKHSPLARGECGSGH
GQDSRKRGRRKRMSAGTPSLSAGVSPKRRALPNVAGLFTQSSGSPLNLSSMVSNINQPLE
ITAISSPETSLKSSPVPYQDHDQPPVLKKERPLGQTNGAHYSPLTSDEEPGSEDEPSSAR
IERKIATISLESRSPPKALENGGGAAGRKLAPASEPVNSSKWKASFEDRYRFGFGSWRDR
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcacgaaatcatcgagacc
atccggtgggtctgtgaggagatcccagatctcaagctggccatggagaattacgtcttg
attgactatgataccaaaagcttcgagagcatgcagaggctgtgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaaagggactacccagcccatgaagctgaacacg
cggccatccaacgggctcctgcggcacatcctgcagcaggtctataaccactcagtgacc
gaccctgagaagctcaacaactacgaacccttctcccccgaggtgtatggggagacctcc
ttcgacctagtggcccagatgatcgacgagatcaagatgacggaggatgacctgttcgtg
gacctgggcagtggtgtaggccaggtggtcctccaggtcgctgctgccaccaactgcaag
caccactacggagtcgagaaagcggacatcccagccaagtacgccgagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggagcgg
ggtgatttcctgtcggaggagtggagagaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgctttgcgaatatg
aaggaaggtgggagaattgtgtcctcaaagccctttgcgcctctgaacttcaggataaac
agcagaaacctgagcgacatcggcaccatcatgcgcgtggtggagctgtcccccctgaag
ggctccgtgtcgtggacggggaagccagtctcctattacctgcacactattgatcgaacc
atacttgaaaattatttttctagtctgaaaaacccaaaactcagggaagaacaagaagct
gctcggcgccgacagcagcgagagaacaagagtaatgcgaccaccccgaccaaggtcccc
gagagcaaggcagccgtccccgccgaggcccccatggattctggtgctgaggaagagaag
acaggggtgaccacagtcaaaaagccttcgccctccaaggcccggaagaagaagctgaac
aagaagggccggaagatggctggacggaagcgtgggcgccccaagaagatgaacgctgcg
aaccctgagcgtaagcccaagaagaatcaaactgcactggatctcctccactcccagacc
gtgtcccagactgcgtcctcctcgccccaggatgcataccggtcccctcacagcccgttc
taccagctacctccaagtgtgccccggcacggccccaacccgctgctggtggcgcccacc
ccgcccgcactgcagaagctgctcgagtcctttaagatccagtacctacagttcctggca
tacacgaagacaccacagtacaaggccaacctgcagcagctgctggaccaggagaaggag
cggaatgcacagttgttgggcacggtgcagcagctctttggacactgccagacccagaag
gaggagatccgcaggctgttccagcagaaactggacgagctgggtgtgaaggcgcttacc
tacaacgacctgatccaagcccagaaggagatctcggcccacaaccagcagctgcgagag
cagtcggagcagctggagaaggacaaccgagcactgcgcggccagagcctgcagctgctc
cgggcgcgctgcgaggagcttaagctggactggtccacgctgtccctggagaagctgcgc
aaggagaagcaggccctgcgcagccagatctccgagaagcagcggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgcgtgcctcctgatgacaccctgccagtgcccctgcgcgggaagagcaccctgggc
agggagctggacactgaggctgctggccggctgcacctggagctggactgcgccaagttc
tccctgccccccttcagcagtgcgagccctgagctctccatgaacggccacgccgctggc
tatgagctctgtagtgtgctgagccggccctcatccaagcagaacaccccgcagtacctg
gcctcccccttggagcaggaggtcgtgccctgcacccccagccacaccggccggccccgg
ctggagcagctgtcggggctggcgctgcccgactacacccggctctccccggccaaagtt
gtgctgcgccggcacctgagtcaggaccacgggggctctgccaaggtggcgaccaatgag
ccacaccctagagccgagcaccccaaggagagcagcctcccctaccagagccctgggctg
ccccctagcatgaagctgagccctcaggacccaaggcccccttcgccaggggcagccccc
caagctggggagaagggcagtgagaagggcgggaaggagcgcatgtatggcagccacggg
gagaccatcaccagcctgcccatcagcatccccctgagcaccgtgcagcccaacaagctc
cccgtcagcatccccctggccagcgtggtgctgcccagccgcgccgagagggtgaggagc
acccccagccccgggccgcagccccgggacgccgcgtctgcgcttgacaaacagatcggt
gctaatgcccacagtgccgggagcaacgcctcagggagccggagcctggccctggcatct
gcaggtttctcctatgcgggctccgtggccatcagtggggccctggctggcagcccggca
ccacccgcacccggcgtggagccagccacctttgatgagccgtcggggagcctgttcgct
accgtggggtcccggagcgccacgccacagcatccacctctgctggcacagcctcggaac
tcaggacctgcgtcccctgcccaccagctctccgccagtccccggctcattggggccacc
cagggtttgcttcctgacatgggcaagggcgaccttcccactgacctgggcttctcagac
cccgagagtgacgccaagagaagaatcgtgttcaccatctcggctggtgcgggcagcgcc
aagcagtccccctccaccaaacacagccccctggcccgcggagagtgcgggtctggccac
gggcaggacagccgaaagcgtggccggaggaagcgcatgtcagccggaacccccagtctg
agtgcaggcgtatcccccaagcggcgcgccctgcccaatgttgccgggctcttcacgcag
tcctcagggtcccctctcaacctcagctccatggtcagcaacatcaaccagccactggag
atcactgctatctcctcccccgagacctccctgaagagctcacctgtgccctaccaggac
catgaccagccgcccgtgctcaaaaaggagcggccgctgggccagaccaacggggcgcac
tactccccgctgacctcggacgaggagcccggctctgaggatgagcccagcagtgcccgc
attgagaggaagatagcaaccatttccctggagagcaggtctccccccaaggccttggag
aacggtggcggcgctgcgggcaggaagctggctccagcgagcgagccggtcaacagcagc
aagtggaaggcctcctttgaagaccgctaccggtttggctttgggtcttggcgggaccgt
taa
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integrated database retrieval system
