Cavia porcellus (domestic guinea pig): 100718484 Help Entry 100718484         CDS       T07777                                  Symbol Insr Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc04010   MAPK signaling pathway cpoc04014   Ras signaling pathway cpoc04015   Rap1 signaling pathway cpoc04022   cGMP-PKG signaling pathway cpoc04066   HIF-1 signaling pathway cpoc04068   FoxO signaling pathway cpoc04072   Phospholipase D signaling pathway cpoc04150   mTOR signaling pathway cpoc04151   PI3K-Akt signaling pathway cpoc04152   AMPK signaling pathway cpoc04211   Longevity regulating pathway cpoc04213   Longevity regulating pathway - multiple species cpoc04520   Adherens junction cpoc04910   Insulin signaling pathway cpoc04913   Ovarian steroidogenesis cpoc04923   Regulation of lipolysis in adipocytes cpoc04930   Type II diabetes mellitus cpoc04931   Insulin resistance cpoc04932   Non-alcoholic fatty liver disease cpoc04960   Aldosterone-regulated sodium reabsorption cpoc05010   Alzheimer disease cpoc05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cpoc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100718484 (Insr)    04014 Ras signaling pathway     100718484 (Insr)    04015 Rap1 signaling pathway     100718484 (Insr)    04066 HIF-1 signaling pathway     100718484 (Insr)    04068 FoxO signaling pathway     100718484 (Insr)    04072 Phospholipase D signaling pathway     100718484 (Insr)    04022 cGMP-PKG signaling pathway     100718484 (Insr)    04151 PI3K-Akt signaling pathway     100718484 (Insr)    04152 AMPK signaling pathway     100718484 (Insr)    04150 mTOR signaling pathway     100718484 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     100718484 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100718484 (Insr)    04923 Regulation of lipolysis in adipocytes     100718484 (Insr)    04913 Ovarian steroidogenesis     100718484 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100718484 (Insr)   09149 Aging    04211 Longevity regulating pathway     100718484 (Insr)    04213 Longevity regulating pathway - multiple species     100718484 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100718484 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100718484 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100718484 (Insr)    04932 Non-alcoholic fatty liver disease     100718484 (Insr)    04931 Insulin resistance     100718484 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cpoc01001]     100718484 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:cpoc04090]     100718484 (Insr) Enzymes [BR:cpoc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      100718484 (Insr) Protein kinases [BR:cpoc01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    100718484 (Insr) CD molecules [BR:cpoc04090]  Proteins   100718484 (Insr) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like fn3 Insulin_TMD Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  100718484 NCBI-ProteinID:  XP_003468418 Ensembl:  ENSCPOG00000012986 UniProt:  H0VMQ0 LinkDB All DBs Position Unknown AA seq 1371 aa AA seqDB search MGAGGAREAPGAPLLLVAVAALLVGVTGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGH LQILLMFKTKPEDFRDLSFPKLVVITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYA LVVFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDN EECGDICPGAAKSKTHCPSTVINGQFVERCWTHTHCQKVCPTACKSHGCTAEGLCCHSEC LGNCTEPDDPTKCVACRNFYLDGRCVATCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQ GCHQYVIHNDRCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGQKTIDSVTSAQELRG CTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGET LEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQ ERNDIALKTNGDQASCENELLKFSFIRTSSDKILLRWEPYWPPDFRDLLGFMLFYKEAPY QNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTF SDERRTYGAKSDIIYVQTDATNPSVPLDPLSVSNSSSQIILKWKPPSDPNGNITHYLVYW QRQAEDSELYELDYCLKGLKLPSRAWSPPLESDDAQKHNQSEYEDAAGECCSCPKTDSQI LKELEESSFRKTFEDYLHNVVFVPRPSRKRRSLGEVANGTALVPTAPSFPGVSTPSVPGS QEEPRPFEKVVNKESLVISGLRHFTGYRIELQACNQGAPEERCSVAAYVSARTMPEAKAD DIVGPVAHEIFDNNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEEMHLCVSRKHYALERGC RLRGLQPGNYSVRIRATSLAGNGSWTEPTYFYVTNYSDVSSNIAKMIIGPLIFVFLFSVV IGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQ GSFGMVYEGNAKDIIKGEAETRVAVKTVNEAASLRERIEFLNEASVMKGFTCHHVVRLLG VVSKGQPTLVVMELMAHGDLKSYLRSLRPESENNPGRPPPTLQEMIQMAAEIADGMAYLN AKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDG VFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRM CWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELELEFEDMENVPLDR SSHCQREEAGGREGGSSLGIKRTYEEHIPYTHMNGGKKNGRILTLPRSSPS NT seq 4116 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggcgcgcgggaggcgccgggcgcgccgctgctgctggtggcggtggcc gcgctgctggtgggcgtcacgggccacctgtaccctggagaggtgtgtccgggcatggac atccggaacaacctcaccaggctgcacgagctggagaactgctccgtcatcgaaggccac ttacagatcctcctgatgtttaagacgaagccagaagacttccgtgacctcagcttcccc aagcttgtggtgatcaccgactacctgttgctctttcgggtctacgggctggagagcctc aaggacctgttccccaacctcaccgtcatccggggctcccgcctcttcttcaactatgcg ctggtggtcttcgagatggtgcacctcaaggagctgggcctctacagcctcatgaacatc acgcgcggctccgtgcgtatcgagaagaacaacgagctgtgctacctggccaccatcgac tggtcgcgcatcctggactccgtggaggacaactacatagtactgaacaaggacgacaac gaggagtgcggggacatctgtccgggcgccgccaagagcaagactcattgcccctccacg gtcatcaacgggcagtttgtggagcgatgctggacccacactcactgtcagaaagtctgc ccgaccgcctgtaagtcccacggctgtaccgctgaaggtctctgctgtcacagcgagtgc ctgggcaactgtacggagcccgacgaccccaccaagtgcgtggcctgccgcaacttctac ctggatggcaggtgtgtggcgacctgcccgccaccctactaccacttccaggactggcgc tgcgtgaacttcagcttttgccaggacctgcacaataaatgcaagaactctcgcaggcag ggctgccaccagtacgtcatccacaacgacaggtgcatccccgagtgtccctctggatac acgatgaattccagcaacttgatgtgtaccccatgcctgggcccctgtcccaaagtctgt catctcctggaaggtcagaagaccatcgactcggtcacctcggcccaggagcttcgaggc tgcacggtgatcaacgggagcctcatcatcaacatccggggaggcaataacctagcagca gagctggaggcgaaccttggcctcattgaagagatttcagggtatctaaaaatccgccgg tcctatgccctggtatcactttctttcttccggaagttgcgcctgattcgaggggaaacc ttggaaattgggaactactcgttctacgccttggacaaccagaacctgaggcagctgtgg gactggagtaagcacaacctcaccatcacgcaggggaagctgttcttccactacaacccc aagctctgcctgtccgagattcacaagatggaagaggtctcggggaccaagggccgccag gagaggaatgacatcgcactcaagaccaacggggaccaggcgtcctgtgaaaatgaatta ctcaaattctctttcatccgtacatcttctgacaagatcttgctgagatgggagccctac tggccgcctgacttcagggacctccttggattcatgcttttctacaaagaggccccatat cagaacgtgaccgagttcgacgggcaggacgcgtgcggctccaatagctggaccgtggtg gacattgacccacccttgagatccaatgaccccaagtcccagaaccaccctgggtggctg atgaggggtctcaagccctggacccagtacgccatctttgtcaagaccttggtcaccttt tctgacgagcgtcggacctacggggccaagagtgacatcatctatgtgcagacggatgcc accaacccgtctgttccactggaccccctctccgtgtctaactcctcgtcccagatcatt ctgaagtggaagccgccctcggaccccaacggcaacatcacgcactacctggtctattgg cagaggcaggcggaagacagcgagttgtacgagctggattactgcctcaaagggctgaag ctgccctccagggcgtggtcgccgccgttggagtccgatgatgcccagaagcacaaccag agcgagtacgaggatgcggccggcgagtgctgctcctgccccaagaccgactctcagatc ctgaaggagctggaggagtcctccttccgcaagaccttcgaggattacctgcacaacgtg gtcttcgtgcccaggccctcccggaaacgcaggtcccttggcgaggtggcgaacgggacc gcattggtgcccacggcacccagcttccctggcgtctccacccccagcgtgcccggcagc caggaggagcccaggcccttcgagaaggtggtgaacaaggagtcgctggtcatctcgggc ctgcgccacttcaccggctatcgcattgagctgcaggcctgcaaccagggcgccccggag gagaggtgcagtgtggccgcctacgtcagcgcccggaccatgcctgaagccaaggcggat gacatcgtcggccctgtggcccacgaaatctttgacaacaatgttgttcacttgatgtgg caagaaccgaaggagcccaacggcctgatcgtgctgtacgaagtgagctatcggcgctac ggggaagaggagatgcatctgtgcgtgtcccgcaagcactatgccctggagcgcggctgc aggctgcgagggctgcagcccggtaactacagcgtgcgcatccgcgccacctccctggcg ggaaacggctcctggaccgagcccacctacttctacgtgacgaattattcagatgtctca tcaaatattgcaaagatgatcatcggccccctcatcttcgtctttctcttcagtgttgtg atcgggagtatttatctattcctgagaaagcgacagccagacggaccgatgggaccgcta tatgcttcctcaaacccagagtacctcagtgccagcgacgtgttcccgtgttctgtgtat gtgccggacgagtgggaggtgcctcgagagaagatcaccctcctgcgagagctggggcag ggctccttcggcatggtgtatgaggggaatgccaaggacatcatcaagggggaggcagag actcgtgtggcggtgaagacggtcaatgaggcggccagtctccgggagaggatcgagttc ctcaacgaggcttcagtcatgaagggcttcacctgtcaccacgtggtccgcctcctgggg gtggtgtccaagggccagccaacactggtggtgatggagttgatggcccatggagacctg aagagctacctccgttccctgcggccagagtctgagaataaccctggccgccctccccct acactgcaagagatgattcagatggcggcggagattgctgatgggatggcatacctgaac gccaagaagtttgtacaccgggacctggcagctcgaaactgcatggtcgcccacgatttt accgtcaaaatcggagactttggaatgacgagagacatctacgaaacggattactatcgg aagggaggcaaaggcctgctccccgtacggtggatggcaccagagtccctgaaggacggg gtcttcactgcttcttccgacatgtggtcctttggtgtggttctttgggaaatcaccagc ctggcagaacagccttaccaaggcctgtccaatgagcaggtgttgaaatttgtcatggat ggagggtacctggaccagcccgacaactgccctgagagagtcactgacctgatgcgcatg tgctggcagttcaaccccaagatgcggccgactttcttggagatcgtcaacctgctgaag gatgaccttcaccccagcttcccagaagtctccttcttccacagtgaggagaacaaggcc cccgagagcgaggagctggagctagagttcgaggacatggagaacgtgcccctggaccgg tcctcgcactgtcagagggaggaggctgggggccgggagggaggatcctcattgggcatc aagcggacctacgaagagcacatcccttacacccacatgaacgggggcaagaagaacggg cggattctgaccctccctcgctccagcccttcctaa

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