KEGG   Cavia porcellus (domestic guinea pig): 100731419
Entry
100731419         CDS       T07777                                 
Symbol
Map2k6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc04010  MAPK signaling pathway
cpoc04015  Rap1 signaling pathway
cpoc04218  Cellular senescence
cpoc04380  Osteoclast differentiation
cpoc04620  Toll-like receptor signaling pathway
cpoc04664  Fc epsilon RI signaling pathway
cpoc04668  TNF signaling pathway
cpoc04750  Inflammatory mediator regulation of TRP channels
cpoc04912  GnRH signaling pathway
cpoc04935  Growth hormone synthesis, secretion and action
cpoc04936  Alcoholic liver disease
cpoc05014  Amyotrophic lateral sclerosis
cpoc05022  Pathways of neurodegeneration - multiple diseases
cpoc05132  Salmonella infection
cpoc05135  Yersinia infection
cpoc05145  Toxoplasmosis
cpoc05161  Hepatitis B
cpoc05163  Human cytomegalovirus infection
cpoc05167  Kaposi sarcoma-associated herpesvirus infection
cpoc05169  Epstein-Barr virus infection
cpoc05170  Human immunodeficiency virus 1 infection
cpoc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cpoc05417  Lipid and atherosclerosis
cpoc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100731419 (Map2k6)
   04015 Rap1 signaling pathway
    100731419 (Map2k6)
   04668 TNF signaling pathway
    100731419 (Map2k6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100731419 (Map2k6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100731419 (Map2k6)
   04664 Fc epsilon RI signaling pathway
    100731419 (Map2k6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100731419 (Map2k6)
   04935 Growth hormone synthesis, secretion and action
    100731419 (Map2k6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100731419 (Map2k6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100731419 (Map2k6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100731419 (Map2k6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100731419 (Map2k6)
   05161 Hepatitis B
    100731419 (Map2k6)
   05163 Human cytomegalovirus infection
    100731419 (Map2k6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100731419 (Map2k6)
   05169 Epstein-Barr virus infection
    100731419 (Map2k6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100731419 (Map2k6)
   05135 Yersinia infection
    100731419 (Map2k6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100731419 (Map2k6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100731419 (Map2k6)
   05022 Pathways of neurodegeneration - multiple diseases
    100731419 (Map2k6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100731419 (Map2k6)
   05418 Fluid shear stress and atherosclerosis
    100731419 (Map2k6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100731419 (Map2k6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cpoc01001]
    100731419 (Map2k6)
Enzymes [BR:cpoc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100731419 (Map2k6)
Protein kinases [BR:cpoc01001]
 Serine/threonine kinases: STE group
  STE7 family
   100731419 (Map2k6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase DUF4344 CLP1_P Choline_kinase APH
Other DBs
NCBI-GeneID: 100731419
NCBI-ProteinID: XP_012997925
Ensembl: ENSCPOG00000035439
UniProt: A0A286XA62
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggcctgaaaattccaaaagaagcattt
gaacaacctcagaccagttctacgccacctagagatttagactccaaggcttgcatttct
attggaaaccagaactttgaggtgaaggcagatgatctggagccaatagtggagctggga
cgaggtgcatatggagtggtggagaagatgcggcatgtacccagtgagcagatcatggca
gtgaagcggatccgggccactgtgaatagccaggagcagaaaaggctattgatggatttg
gatgtctccatgagaacagtagactgtccatttactgtcacgttctatggtgcacttttc
cgggagggagatgtgtggatctgcatggagctcatggatacgtcactagataaattctac
aaacaagttattgataaaggccaaacaattccagaggatatcctagggaagatagcagtt
tctattgtaaaagcactagaacatttacacagtaagctctctgtcattcatcgggacgtc
aagccttcgaatgtgctaattaataccctgggccaagtgaagatgtgtgactttggaatc
agtggctacctggtggactctgttgctaaaacaattgatgcaggttgcaaaccatacatg
gcccctgaaagaataaatccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcactatgattgagctggccatccttcggtttccctacgattcgtgg
ggaactccctttcagcagctcaaacaggtggtagaggagccatcaccacagctcccagca
gacaagttctctgcagagtttgtggacttcacctcacaatgcttgaagaagaattccaaa
gaacggcctacataccccgagcttatgcaacatccatttttcaccctacatgaatccaaa
gcaacagatgtggcgtcttttgtaaaactgattcttggagactaa

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