Cavia porcellus (domestic guinea pig): 100735725
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Entry
100735725 CDS
T07777
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00010
Glycolysis / Gluconeogenesis
cpoc00020
Citrate cycle (TCA cycle)
cpoc00620
Pyruvate metabolism
cpoc00785
Lipoic acid metabolism
cpoc01100
Metabolic pathways
cpoc01200
Carbon metabolism
cpoc01210
2-Oxocarboxylic acid metabolism
cpoc04066
HIF-1 signaling pathway
cpoc04922
Glucagon signaling pathway
cpoc05230
Central carbon metabolism in cancer
cpoc05415
Diabetic cardiomyopathy
Module
cpoc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100735725 (Pdha1)
00020 Citrate cycle (TCA cycle)
100735725 (Pdha1)
00620 Pyruvate metabolism
100735725 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100735725 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100735725 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100735725 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100735725 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100735725 (Pdha1)
Enzymes [BR:
cpoc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100735725 (Pdha1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100735725
NCBI-ProteinID:
XP_003466441
Ensembl:
ENSCPOG00000009280
UniProt:
H0VE97
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSRAAQKPSSRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGHHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgcttgccgccgtctcccgcgtgttgtcccgcgctgcccagaagccgtca
agcagagtactagtggcatcccgtaattttgcaaatgatgctacgtttgaaattaagaaa
tgtgatcttcaccggctggaagagggcccacctgtcaccaccgtgctcaccagggaggat
ggactcaagtactacaggatgatgcagactgtgcgccgaatggagttaaaggcagaccaa
ctgtataagcagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcctgc
tgcgtgggacttgaggccggcataaaccctacagaccatctgatcacagcctaccgggct
catggctttaccttcactcggggcctttctgtccgggagattctagcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggaggatctatgcacatgtatgccaagaacttc
tacggtggcaatggcattgttggagctcaggtgcccctgggagctggaattgctctggcc
tgcaagtacaatggaaaagatgaagtctgtttgacattatatggtgatggtgctgccaat
cagggtcagatatttgaagcttacaatatggcagcattgtggaaattaccctgtattttc
atctgtgagaataaccgctatggaatgggaacgtctgttgagcgagccgcagccagcact
gattactataagagaggcgattttattccagggctgagggtagatggaatggatatcctg
tgtgtgcgagaagcaacaaggtttgcagctgcctattgtagatctgggaagggacctatc
ctgatggagctgcaaacttaccgttaccatggacatagtatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgacccgattatgcttctc
aaggataggatggtgaacagcaatcttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccacagctgatcccgagccacct
ctggaagaactaggccatcacatctacagtagtgacccaccctttgaagtgcgtggtgct
aaccagtggatcaaattcaagtcagtcagttaa
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