Corynebacterium resistens: CRES_1949
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Entry
CRES_1949 CDS
T01538
Symbol
hemD
Name
(GenBank) uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
crd
Corynebacterium resistens
Pathway
crd00860
Porphyrin metabolism
crd01100
Metabolic pathways
crd01110
Biosynthesis of secondary metabolites
crd01120
Microbial metabolism in diverse environments
crd01240
Biosynthesis of cofactors
Module
crd_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
crd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CRES_1949 (hemD)
Enzymes [BR:
crd01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CRES_1949 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CRES_1949 (hemD)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AEI10302
UniProt:
F8E2S9
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Position
complement(2311015..2312853)
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AA seq
612 aa
AA seq
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MHPARVAKIESRTDMTVSGMDPVGQQGRVLFVGAGPGNPELLTVRARDVIEHTAYAWVDP
AVLNGVQSLIAAKVPVPQHKLDAAEKEWEQRVAAAREAGARRRPPRPEPPTAAEIVFAAP
GAAVDADGDDADEAATAATEGGEDSAAVMVPADPVVIAQQMVACAKAGNDVIRLVAGNPL
STPGVLLELQEVENLGVEFQVVPGMTGSVAVPAFTGIRVGPDVTTADVRGGTDWDQLAGA
GLPLILTAAPSDLMGIASELKARSIPGSTPATVTLHGTTRRQRSYDVTLDTLKSIAAASG
PAAKEGELPDELIVTIGSEVGNRSKYSWWENRALYGWTVLVPRAKNQAGPMSARLASHGA
IPVEVPTISVEPPRTPVQMERAIKGIVDGHYHWVVFTSVNAVKATWEKLQEFGLDARALA
GVRVAAVGPKTAQSVLDLGITPELLPKDNARNASGLVDVFPAYDPDVDMVDKVLLPRADI
ATDVLVDGLIDLGWDVEDVVAYRTVRAAPPSPEIRDMIKTGGFDAVCFTSSSTVKNLVGI
AGKPHARTIIACIGPMAAQTAREHGLRVDVMPEAAGVPELVDALAEHVADLRAKGQLPPP
RKRRRRRKKTSS
NT seq
1839 nt
NT seq
+upstream
nt +downstream
nt
gtgcatccagcacgggtagcgaaaatagaaagccgtaccgacatgactgtttccggaatg
gaccctgtgggtcagcagggccgagtgctctttgtgggtgccggcccaggtaacccggaa
ttgctgaccgtccgcgcacgcgacgtcatcgaacacaccgcttatgcctgggtggatcca
gcggtgctcaacggagtgcagtccctgattgctgccaaagtgcccgtgcctcagcacaag
ctggatgctgcagaaaaggaatgggaacagcgcgtggctgctgcgcgcgaagccggtgct
cgtcggcgtccaccgcgaccggagcctccaacggcggcggagatcgtttttgcggcgccg
ggcgctgcggtggatgccgatggggatgacgccgatgaggccgcaaccgccgctaccgag
ggtggcgaagactcggccgccgtcatggtcccagctgatccggtggttatcgctcagcaa
atggtcgcgtgtgcgaaggccggcaacgatgttattcgcctagtggctggcaacccgttg
agcacgccgggggttttgctggagctgcaagaggtagagaacctgggcgtagagttccaa
gtcgtacctggcatgactgggtctgtggcggtacccgcgtttaccggtatccgtgtcggg
ccagatgtgaccactgccgatgtgcgaggaggaacggattgggatcagctcgccggtgcc
ggcttaccgttgatcctcactgctgcgccaagcgacttgatgggcattgcctcggagttg
aaggcgcgtagcatcccgggctccactccggcgacagtaactttgcacggcacgacccgt
cgccagcgtagctacgatgtcacgctggatacgctgaagtcgatcgctgctgcttccggg
cccgctgctaaggaaggcgagctcccagacgaacttatcgtcacgatcggtagtgaagtt
ggcaatcgctccaagtactcgtggtgggaaaatcgcgcgctgtatggatggaccgttcta
gtcccccgtgcgaaaaaccaagctgggccgatgagcgcccgtttggcctcccatggtgca
attccagtggaggtgcccacgatctccgtggagccacctcgcacacctgttcagatggaa
cgtgcgatcaaggggatcgtggatgggcactatcactgggtggtgttcaccagcgttaac
gcagtgaaggctacgtgggagaagctccaggagtttggcctcgatgcccgagccctcgcc
ggagtacgcgtggcggctgtggggccgaagaccgcacaatccgtcctcgacctcggtatc
accccagagctgttgccaaaggataatgcgcgcaacgcttcgggcttggtggacgttttc
cctgcttacgatcctgacgtggacatggtggataaggttttgctgccacgtgccgatatc
gccacggacgtgctcgtcgatggcctcatcgaccttggctgggatgtggaagatgtcgtg
gcctaccgcaccgtgcgggcggccccgccgagccccgagattcgcgacatgatcaagacc
ggtggcttcgacgcagtctgcttcacgtcctcttcgaccgtcaaaaatctcgtcggcatc
gcgggtaagccacatgcgcgcaccatcattgcttgcatcggaccgatggcagcccaaacc
gcgcgtgaacatggcctccgcgtggatgtcatgcccgaagcggccggggtaccggagctc
gtggacgcactagcggagcatgtggccgatctgcgcgcgaagggccagctgccacctcct
cggaagaggcggcgtcggaggaagaaaacctccagctaa
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