Clostridium scindens: HDCHBGLK_00152
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Entry
HDCHBGLK_00152 CDS
T06591
Symbol
dmdA_1
Name
(GenBank) 2,3-dimethylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
csci
Clostridium scindens
Pathway
csci00290
Valine, leucine and isoleucine biosynthesis
csci00660
C5-Branched dibasic acid metabolism
csci01100
Metabolic pathways
csci01110
Biosynthesis of secondary metabolites
csci01210
2-Oxocarboxylic acid metabolism
csci01230
Biosynthesis of amino acids
Module
csci_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
csci00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HDCHBGLK_00152 (dmdA_1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HDCHBGLK_00152 (dmdA_1)
Enzymes [BR:
csci01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HDCHBGLK_00152 (dmdA_1)
4.2.1.35 (R)-2-methylmalate dehydratase
HDCHBGLK_00152 (dmdA_1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
OspD
DUF2783
Motif
Other DBs
NCBI-ProteinID:
QBF72807
UniProt:
B0NJ74
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All DBs
Position
complement(162235..163509)
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AA seq
424 aa
AA seq
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MGMTMTQKILAAHAGLDSVEAGQLIEAKLDVVMANDITGPMAVPVFRQMADKVFDKDKVI
LVPDHFTPNKDIKSAENSKSIREFAKEQGLTHYYEVGQMGIEHAILPEKGITVAGECIIG
ADSHTCTYGALGAFSTGVGTTDIATGMATGELWFKVPSAIKFVLTGKPGPYVSGKDIIIH
IIGRIGVDGALYKSMEFVGDGIASLTMDDRFTMANMAIEAGAKNGIFLVDEKAEEYMKEH
SDKEYKIYEADADADYDAVVEVDLAKVRPTVAFPHLPGNAKTIDEIEAMEPIKIDQVVIG
SCTNGRMEDMRRAAAVLKGRKVHPDVRVMVIPATQKIYKQCIKEGLVDIFIDAGCAFNTP
SCGPCMGGHMGVLAAGEKCVSTTNRNFVGRMGHVDSLIYLASPEVAAASAIAGCIANPEK
VGDR
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgacaatgacacagaagattcttgcagcccatgcgggacttgacagcgttgaa
gccggacagttgatcgaggcgaagttggatgtggttatggcaaacgatattacagggcct
atggcggttcctgtattcaggcagatggcagataaagtgttcgacaaggataaggtgatt
ctggtaccagatcattttacgccgaacaaggacatcaaatccgccgagaactccaaatcc
atccgcgagttcgcgaaagaacagggtctgacgcattattatgaagtgggacagatggga
atcgagcatgcgatcctgccggaaaaaggaattacagtggcaggagaatgcattataggc
gcagattcccacacttgtacatatggagcattgggggcattttctaccggagtagggacg
acggatatcgcgacaggaatggctaccggggaactgtggttcaaggtgccaagcgcgatc
aagttcgtgcttacaggtaagccggggccatatgtaagcggcaaggatatcatcatccat
attataggaaggatcggcgtggacggcgcactgtacaaatcaatggaatttgtaggagac
ggcattgcaagtctaaccatggatgatcgatttaccatggcaaatatggcgattgaggca
ggtgcaaagaatggaatctttctggtcgatgaaaaggccgaggaatatatgaaggaacat
tccgataaagaatacaagatctacgaggcagatgcagatgccgactatgacgcggtagtg
gaagtagatctggcgaaggtccgccctacggtagcattcccgcatcttccgggaaatgca
aagacgatcgatgaaatagaggcaatggagccaattaagattgatcaggtagtcatcggc
tcttgtaccaacggaagaatggaggatatgagaagagcggcggccgtgcttaaagggcgg
aaggtacatccagatgttcgtgtcatggtcattcctgcgacacagaagatctataagcag
tgtatcaaagaagggctggtagacatctttattgatgcaggatgcgcgttcaatacgcca
agctgcggaccttgcatgggaggccatatgggcgtcctggcagcaggagagaagtgcgtc
tctacaacaaacaggaactttgtcggaagaatggggcacgtagattccctgatctatctt
gcatccccggaagtggcagcggccagcgcgatcgcgggatgtattgcgaatccagagaaa
gtaggtgacagataa
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