Corynebacterium silvaticum: CBE74_01825
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Entry
CBE74_01825 CDS
T07501
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
csil
Corynebacterium silvaticum
Pathway
csil00860
Porphyrin metabolism
csil01100
Metabolic pathways
csil01110
Biosynthesis of secondary metabolites
csil01120
Microbial metabolism in diverse environments
csil01240
Biosynthesis of cofactors
Module
csil_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
csil00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CBE74_01825
Enzymes [BR:
csil01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CBE74_01825
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CBE74_01825
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ARU45449
UniProt:
A0A7Y4LID1
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Position
364748..366436
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AA seq
562 aa
AA seq
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MSSTPQPTPVTPLPEGKVIFVGAGPGNPDLLTVRAREVLSHTAFAVVDAEVLPGVRSVVA
RELDVPGDKIQAAEEEYERLCAEAKEAGARRKPQRPDAPTAAEITEVDDDVPVAEVVDKL
KELLTTGEDVIRLVQGNPLSCDRTLEEISAVTQAGLEFHIVPGMSLPATVPAFAGIALGS
SYTETDVTGEDVDWEQLAAAPQPLVLQATKEDLPTIAAELKARGLGASTPVTVTAHGTTR
LQRSFDVTLGTLSKLDGDLAGTLVVTLGKAVDDRTKYSWWENRSLFGWRVLVPRAKEQAG
PMSTLLASQGAIPQEVPTISVEPPRNPAQMEKAIKGIVEGRYQWVIFTSVNAVKAVREKI
GSFGLDARAFAGVRIGAVGTKTAKAIRELGITPELLPPRNQQNAAGLVSVFPEYVEDLDP
VGRVLLPRADIATDVLVEGLEGLGWEVDDVVAYRTVRAAPPSAEVRDMIKSGGFDAVCFT
SASTVKNLVGIAGKPHQRTIIACIGPMAEAAAKELGLRVDVVPEVADVPHLVNSLAAHVA
QLRAAGQLPPPRKKRRARKNRE
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgagttcaactccgcagcccactccggtcacccctttgccggagggaaaagtgatcttc
gtaggagcaggcccaggaaaccctgacctgctcaccgttcgcgcccgtgaagttctcagc
cataccgcttttgccgtagtagacgcagaagtgctaccgggagttcgctcagtagtcgca
cgtgaactagacgttccgggagataagatccaggcggctgaggaagaatacgagcgcctc
tgcgcggaggcaaaagaggccggcgcccgccgtaaaccgcagcgcccggacgccccgacc
gctgctgagattactgaagtagacgatgacgttccggtggcggaggtcgtcgacaagctt
aaggagcttttgaccaccggcgaggacgttatccgcctcgtgcagggtaaccctctatcc
tgcgaccgcactctggaagaaatatccgcagtcactcaggctggactggaattccacatt
gttccaggtatgtccttgcctgctaccgttccggcttttgcgggtatcgcgctggggtct
tcctatacggaaactgacgtgaccggtgaagacgtggattgggaacagttggcggcagca
ccccagccactggttttacaggcgaccaaagaagacctgcccacaatagcggcagaactc
aaagcccgtgggctgggggcatcgaccccggtgacggtgaccgctcacggcacgacgcgt
ttgcagcgaagttttgacgtcactctgggtactctgagcaagctagacggggacctcgct
ggcactctcgtggtcaccttaggcaaagccgtggacgatcgcaccaaatactcctggtgg
gagaatcgctctctctttggctggcgagtcctggtgccgcgagctaaagaacaagccggc
cccatgagcacattgctggcttcgcagggggcaatcccgcaagaagtccccacgatctcc
gtggaaccgccgcgcaaccccgcgcaaatggagaaagccatcaagggaatcgtcgaggga
cgctaccagtgggtgatctttaccagcgttaatgcggtgaaagctgtgcgagaaaagatc
ggctctttcggcctcgatgcccgcgcctttgccggcgtacgcatcggcgcggtagggaca
aaaaccgctaaggcgatccgcgagctcggaattactcccgagctgctaccgccgaggaat
cagcaaaatgccgcaggcttggtgtcggtgttcccggaatacgtggaagaccttgacccg
gtgggacgagtccttttgcctcgcgcagatattgcaacggacgtcctggtagaaggccta
gagggccttggctgggaggtcgatgatgtggtcgcgtatcgcacggtacgcgctgcaccg
ccgagcgcggaagtgcgcgacatgattaaaagcggcggttttgacgcagtgtgctttacc
tctgcgtcgacggtgaaaaatctggtgggcatcgccgggaaaccgcatcagcgcacgatc
attgcatgcatcgggcccatggcggaggccgcggcaaaagagttaggcctgcgcgtggac
gtggtccctgaggtggcggacgtcccgcatctggtaaacagccttgctgctcatgtggca
caactacgagcggccggtcagctgccgccgcctaggaagaaacggcgcgcccggaaaaat
cgcgagtaa
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