Carlito syrichta (Philippine tarsier): 103262860 Help Entry 103262860         CDS       T07836                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism csyr  Carlito syrichta (Philippine tarsier) Pathway csyr01521   EGFR tyrosine kinase inhibitor resistance csyr04151   PI3K-Akt signaling pathway csyr04217   Necroptosis csyr04380   Osteoclast differentiation csyr04550   Signaling pathways regulating pluripotency of stem cells csyr04620   Toll-like receptor signaling pathway csyr04621   NOD-like receptor signaling pathway csyr04630   JAK-STAT signaling pathway csyr04658   Th1 and Th2 cell differentiation csyr04659   Th17 cell differentiation csyr05140   Leishmaniasis csyr05145   Toxoplasmosis csyr05152   Tuberculosis csyr05160   Hepatitis C csyr05161   Hepatitis B csyr05162   Measles csyr05163   Human cytomegalovirus infection csyr05164   Influenza A csyr05165   Human papillomavirus infection csyr05166   Human T-cell leukemia virus 1 infection csyr05167   Kaposi sarcoma-associated herpesvirus infection csyr05168   Herpes simplex virus 1 infection csyr05169   Epstein-Barr virus infection csyr05171   Coronavirus disease - COVID-19 csyr05200   Pathways in cancer csyr05203   Viral carcinogenesis csyr05212   Pancreatic cancer csyr05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:csyr00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     103262860 (JAK1)    04151 PI3K-Akt signaling pathway     103262860 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     103262860 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     103262860 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     103262860 (JAK1)    04621 NOD-like receptor signaling pathway     103262860 (JAK1)    04658 Th1 and Th2 cell differentiation     103262860 (JAK1)    04659 Th17 cell differentiation     103262860 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     103262860 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103262860 (JAK1)    05203 Viral carcinogenesis     103262860 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103262860 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     103262860 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103262860 (JAK1)    05161 Hepatitis B     103262860 (JAK1)    05160 Hepatitis C     103262860 (JAK1)    05171 Coronavirus disease - COVID-19     103262860 (JAK1)    05164 Influenza A     103262860 (JAK1)    05162 Measles     103262860 (JAK1)    05168 Herpes simplex virus 1 infection     103262860 (JAK1)    05163 Human cytomegalovirus infection     103262860 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     103262860 (JAK1)    05169 Epstein-Barr virus infection     103262860 (JAK1)    05165 Human papillomavirus infection     103262860 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     103262860 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     103262860 (JAK1)    05140 Leishmaniasis     103262860 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103262860 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:csyr01001]     103262860 (JAK1) Enzymes [BR:csyr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      103262860 (JAK1) Protein kinases [BR:csyr01001]  Non-receptor tyrosine kinases   JAK family [OT]    103262860 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  103262860 NCBI-ProteinID:  XP_008058697 Ensembl:  ENSTSYG00000006932 UniProt:  A0A1U7U068 LinkDB All DBs Position Unknown AA seq 1152 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEGSLEALEPGVEVLFYLPDREALRLGGGEYTAEEL CIQAAQECRISPLCHNLFALYDESTRLWYAPNHTITVDDKVSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDANSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMRKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHSNDSGNLLYYEVMVTGNLGIQWRQKPNVVPVEKEKKLKRKKLENKHKKDEEKNKIRE EWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHH YLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTC FEKSEVQGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGELMGHLKKQILRTDNISFVLKR CCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGTL MDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE NIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL AREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT LWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIM RDINKLEEQNPDIVSERKPAAEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSG SLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDS SPMALFLRMIGPTHGQMTVTRLVATLKEGKRLPCPPGCPDEVYQLMRKCWEFQPTNRTTF QNLIEGFEALLK NT seq 3459 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaacatcaaagaggactgcaatgccatggctttctgcgcgaaaatgagg agctccaagaagaccgaggggagtctggaggccctcgagccaggcgtggaagtactcttc tatctgccggacagggaggccctccggctgggcggtggggagtataccgcggaggagctg tgcatccaggccgctcaagagtgccggatctcccctctgtgccacaacctcttcgccctg tatgacgagagcaccaggctctggtacgctccgaaccacaccatcaccgtggatgacaag gtgtcgctccggctccactaccggatgaggttctatttcaccaattggcacgggaccaat gacaatgagcagtcggtgtggcgacattctccaaagaagcagaagaatggctatgagaag aaaaaggttccagatgcaactcctctccttgacgccaactcgctggagtatctgtttgcc cagggacagtatgacttggtgaaatgcctggctcccatccgagaccccaagactgagcag gatgggcacgacattgagaacgagtgtctggggatggccgtcctggccatctcacactat gccatgatgaggaagatgcagttgccggaactgcccaaggatatcagttataagcgatat attccagaaaccctgaataaatccatcagacagaggaaccttctcaccaggatgcggata aataacgttttcaaggatttcctaaaggaattcaacaacaaaaccatttgtgacagcagc gtgtccactcatgacctgaaggtgaaatacctggctaccttggagaccttgacaaaacat tacggtgctgaaatattcgagacttccatgttactgatttcatcagaaaatgagatgaat tggtttcattcaaatgacagtggaaaccttctctactatgaagtgatggtgactggaaat cttggcatccagtggaggcagaagccaaacgttgttcctgttgaaaaggaaaaaaaactg aagcggaaaaaactggaaaacaaacacaagaaggatgaggagaaaaacaaaatccgggaa gagtggaacaacttttcttacttccctgaaatcactcacattgtcataaaggagtctgtg gtcagcattaacaagcaggacaacaaaaaaatggaactgaagctgtcttcccacgaggag gccttgtccttcgtgtccctggtagacggctacttccggctcactgcagatgcccatcat tacctctgcacagacgtggcccccccgttgattgtccacaacatacagaacggctgtcac ggtccaatctgcacagaatacgccatcaataaactgcggcaggagggcagcgaagagggt atgtatgtgctgaggtggagctgcaccgactttgacaacatcctcatgaccgtcacctgc tttgaaaagtctgaggtgcagggtggccagaagcagttcaagaacttccagatcgaggtg cagaagggccgctacagcctgcatggctccgaccgcagcttccccagcttgggagaactc atgggccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaagcgc tgctgccagcccaagccccgagaaatctccaacctgctggtggctaccaagaaagcccag gagtggcagcccgtctaccccatgagccaactgagtttcgatcggatcctcaagaaggac attgtgcagggtgagcacctcgggagaggcacgaggacacacatctactccgggaccctt atggactacaaggatgacgaggggacttctgaggagaagaagataaaagtgatcctcaaa gtcttagaccccagccacagggacatctctctggccttcttcgaggcagccagcatgatg agacaggtttcccacaagcacatcgtgtacctctatggcgtctgtgtccgggacgtggag aatatcatggtagaagagttcgtggaagggggccccctggacctcttcatgcaccggaag agtgacgtcctcaccactccgtggaagttcaaggttgccaaacagctggccagcgccctg agctacttggaagataaagacctggtccatgggaacgtgtgcacgaaaaacctgctcctg gcccgcgagggcatcgacagcgagtgcggcccattcatcaagctcagcgaccccggcatc cccatcactgtgctgtccaggcaagagtgcatagagcggatcccgtggattgcccccgag tgtgtggaggactccaagaacctgagtgtggctgccgacaagtggagcttcggtaccacg ctctgggaaatctgctacaacggcgagatccccctgaaagacaagaccctgattgagaaa gagagattctatgaaagccgatgcaggccagtgacaccatcgtgtaaggagctggctgac ctcatgacccgctgcatgaactatgaccccaatcagagacccttcttccgagccatcatg agagacatcaacaagctcgaggagcagaatccagacattgtttctgaaagaaaaccggca gccgaagtggatcccacgcattttgaaaagcgcttcctgaagaggatccgagacttggga gagggccattttgggaaggtggagctctgcagatatgatcctgagggggacaacaccggg gagcaggtggctgtcaaatctctgaagcccgagagcggagggaaccacatagctgatctg aagaaggagatagaaatcctgcggaacctctatcatgagaacatcgtgaagtacaaaggc atctgcacggaagacggaggaaatggtattaagctcatcatggaattcctgccttcggga agccttaaggagtatcttccaaagaataagaacaaaattaaccttaaacagcagctgaaa tatgccgttcagatttgtaagggcatggactatttgggttctcggcaatacgttcaccgg gacttagcagcaaggaatgtccttgtcgagagtgaacaccaagtgaaaataggagacttt ggtttaaccaaagccattgaaaccgacaaggagtattacactgtcaaggacgaccgggac agccctgtgttttggtatgccccagagtgtttgattcagtgtaagttttatattgcctcc gacgtctggtcttttggagtgaccctgcatgagctgcttacttactgtgattccgattct agtcccatggctttgttcctgagaatgataggcccaactcatggccagatgacagtcaca aggctcgtggccacactgaaagaaggaaagcgcttgccatgcccacccggctgtccagat gaggtttatcaacttatgagaaaatgctgggaattccaacccaccaatcggacaaccttt cagaaccttattgaaggatttgaagcacttttaaaataa

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