Carlito syrichta (Philippine tarsier): 103265992
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Entry
103265992 CDS
T07836
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr00010
Glycolysis / Gluconeogenesis
csyr00020
Citrate cycle (TCA cycle)
csyr00620
Pyruvate metabolism
csyr00785
Lipoic acid metabolism
csyr01100
Metabolic pathways
csyr01200
Carbon metabolism
csyr01210
2-Oxocarboxylic acid metabolism
csyr04066
HIF-1 signaling pathway
csyr04922
Glucagon signaling pathway
csyr05230
Central carbon metabolism in cancer
csyr05415
Diabetic cardiomyopathy
Module
csyr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103265992 (PDHA1)
00020 Citrate cycle (TCA cycle)
103265992 (PDHA1)
00620 Pyruvate metabolism
103265992 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103265992 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103265992 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
103265992 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103265992 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103265992 (PDHA1)
Enzymes [BR:
csyr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
103265992 (PDHA1)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
103265992
NCBI-ProteinID:
XP_008061827
Ensembl:
ENSTSYG00000006218
UniProt:
A0A1U7U985
LinkDB
All DBs
Position
Unknown
AA seq
433 aa
AA seq
DB search
MTPSRRPAVKAWRLRGHLKETCGHPDGVSPAFGSCRNPHCLRSMRKMLAAVSRVLSGAAQ
KPANRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG
AANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYFKRGDFIPGLRVDGM
DILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPI
MLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEV
RGANQWIKFKSVS
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgactccatcacgtcgccctgcagttaaggcgtggcgtttgcgggggcacctgaaggag
acttgcggacaccctgacggtgtttctccggcgtttgggagttgccgcaacccacactgc
ctgcgttccatgaggaagatgctcgccgctgtctcccgcgtgttgtctggtgcagcccag
aagccggcaaacagagtgctggtagcgtcccgtaattttgcaaatgatgctacatttgaa
attaagaaatgtgaccttcaccggctggaagaaggccctcctgtcacgacagtgctcacc
agggaggacggcctcaaatactacaggatgatgcagactgtgcgccggatggagttaaag
gcagatcagctatataaacagaaaattattcgtggtttctgtcacttgtgtgacggtcag
gaagcttgctgtgtaggcctggaggccggcataaatcccacagaccatctcatcacagcc
tatcgggctcacggctttaccttcactcggggcctttctgtccgagaaattcttgcagag
cttacaggacgtaaaggaggttgtgccaaaggaaaaggaggatcaatgcatatgtatgcc
aagaacttctacgggggcaatggcattgtgggagctcaggtgcccctgggagctggaatt
gctctggcctgtaagtataatgggaaagatgaggtctgcctgactttatatggtgatggt
gctgctaatcagggtcagatattcgaagcttacaacatggcagctttgtggaaattgcct
tgtattttcatctgtgagaataaccgctatggaatgggaacatctgttgagagagcagca
gccagcactgattacttcaagagaggcgattttattcctgggctgagggtagatggaatg
gatatcttgtgtgtccgagaggcaacaaggtttgcagctgcctactgtagatctgggaag
gggcccattctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcct
ggagtcagttaccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatt
atgctgctcaaggatagaatggtgaacagcaatcttgctagtgttgaagaattaaaggaa
attgatgtggaagtgaggaaagaaattgaggatgctgcccagtttgcaacagctgatcct
gagccgcctttggaggaactagggtatcacatctactccagcgacccaccttttgaagtc
cgtggtgccaatcagtggatcaagtttaaatcagtcagttaa
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