Carlito syrichta (Philippine tarsier): 103273081 Help Entry 103273081         CDS       T07836                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism csyr  Carlito syrichta (Philippine tarsier) Pathway csyr04010   MAPK signaling pathway csyr04014   Ras signaling pathway csyr04015   Rap1 signaling pathway csyr04022   cGMP-PKG signaling pathway csyr04066   HIF-1 signaling pathway csyr04068   FoxO signaling pathway csyr04072   Phospholipase D signaling pathway csyr04150   mTOR signaling pathway csyr04151   PI3K-Akt signaling pathway csyr04152   AMPK signaling pathway csyr04211   Longevity regulating pathway csyr04213   Longevity regulating pathway - multiple species csyr04520   Adherens junction csyr04910   Insulin signaling pathway csyr04913   Ovarian steroidogenesis csyr04923   Regulation of lipolysis in adipocytes csyr04930   Type II diabetes mellitus csyr04931   Insulin resistance csyr04932   Non-alcoholic fatty liver disease csyr04960   Aldosterone-regulated sodium reabsorption csyr05010   Alzheimer disease csyr05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:csyr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103273081 (INSR)    04014 Ras signaling pathway     103273081 (INSR)    04015 Rap1 signaling pathway     103273081 (INSR)    04066 HIF-1 signaling pathway     103273081 (INSR)    04068 FoxO signaling pathway     103273081 (INSR)    04072 Phospholipase D signaling pathway     103273081 (INSR)    04022 cGMP-PKG signaling pathway     103273081 (INSR)    04151 PI3K-Akt signaling pathway     103273081 (INSR)    04152 AMPK signaling pathway     103273081 (INSR)    04150 mTOR signaling pathway     103273081 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     103273081 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103273081 (INSR)    04923 Regulation of lipolysis in adipocytes     103273081 (INSR)    04913 Ovarian steroidogenesis     103273081 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103273081 (INSR)   09149 Aging    04211 Longevity regulating pathway     103273081 (INSR)    04213 Longevity regulating pathway - multiple species     103273081 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     103273081 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     103273081 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103273081 (INSR)    04932 Non-alcoholic fatty liver disease     103273081 (INSR)    04931 Insulin resistance     103273081 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:csyr01001]     103273081 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:csyr04090]     103273081 (INSR) Enzymes [BR:csyr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      103273081 (INSR) Protein kinases [BR:csyr01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    103273081 (INSR) CD molecules [BR:csyr04090]  Proteins   103273081 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  103273081 NCBI-ProteinID:  XP_008068726 Ensembl:  ENSTSYG00000001830 UniProt:  A0A1U7US90 LinkDB All DBs Position Unknown AA seq 1345 aa AA seqDB search MDIRNNLTRLHELENCSVIEGHLQILLMFKTKPEDFRDLSFPKLIMITDYLLLFRVYGLE SLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLAT IDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQK VCPTICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQD WRCVNFSFCQDLHNKCKNSRRQNCPLYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPK VCPIPEGEKTIDSVTSAQELRGCTVINGSLIINVRGGNNLAAELEANLGLIEEISGYLKI RRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHY NPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSSIRTTSDKILLKWE PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQNHPG WLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQ IILKWKPPSDPNGNITHYLVFWERQEEDSELYELDYCLKGLKLPSRTWSPPFESEDSQKH NQSEYEESAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRETSPGTGAEDTRP SRKRRSLGAIGNVTAAAPTVAAFLNTTSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTG YRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEVFENNIVHLMWQEPKEP NGLIVLYEVSYRRYGDEELHLCVSRKHYALERGCRLRGLSPGNYSVRVRATSLAGNGSWT EATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNP EYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIVKGEPETRVAVK TVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRS LRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGD FGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPY QGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLDIVNLLKDDLHPS FPEVSFFHSDENKAPEAEELEMEFEDMESVPLDRSSHCQREEAGGREGGSSLGLKRNYEE HIPYTHMNGGKKNGRILTLPRSNPS NT seq 4038 nt NT seq  +upstreamnt  +downstreamnt atggatatccggaacaacctcaccaggttgcatgagctggagaactgctcggtcatcgag ggccacttgcagatactcctgatgttcaaaacgaagccggaagacttccgagacctcagt ttccccaagctcatcatgatcaccgattacctgctgctcttccgggtctacggactggag agcctgaaggacttgttccccaacctcacggtcatccggggctcgcggctcttcttcaac tatgcgctggtcatcttcgagatggttcacctgaaggagctcggcctctacagcctgatg aatatcacccggggttccgtccgcatcgagaaaaacaatgagctctgctacttggccacc atcgactggtcccggatcctggactctgtggaggataactacatcgtgctgaacaaggat gacaatgaggagtgcggggacatctgtccgggcaccgcgaagggcaagaccaactgcccc gccaccgtcatcaacgggcagtttgttgagcgctgttggacgcacagtcattgccagaaa gtctgcccgaccatctgtaagtcacatggctgtaccgccgagggcctttgctgccacagc gagtgcttggggaactgctccgagcctgatgaccccaccaagtgcgtggcctgccgcaac ttctacctggacggcaggtgtgtggagacctgcccacccccatactaccacttccaggac tggcgctgcgtgaacttcagcttctgccaggatctgcacaacaaatgcaagaactcacgg cggcagaactgtcccctttatgtcattcacaacaacaagtgtatccctgagtgcccttct gggtacacgatgaactccagcaacctgatgtgcaccccctgcctgggcccctgtcccaag gtctgccccatcccggaaggtgagaagaccatcgactcagtgacgtcggcccaggagctc cgaggatgcaccgtcatcaacggcagcctgatcatcaacgtccgaggaggcaacaacctg gcagctgagctagaagccaacctcggcctcattgaagaaatttcggggtatctaaaaatt cgccgatcctacgcactggtgtcactttctttcttccggaagttacgtctgattcgagga gagaccttagaaatcgggaactactccttctatgccctggacaaccaaaacctgaggcag ctctgggactggagcaagcacaacctcaccatcacgcagggcaagctcttcttccactac aaccctaagctctgtttgtcggaaatccacaagatggaagaagtttccggaaccaagggg cgacaggagagaaacgacatcgccctgaagaccaatggggaccaggcatcctgtgaaaat gaattacttaaattttcttccatccggacaacgtctgacaagatcttgctgaaatgggag ccgtactggcccccagacttccgagacctcttggggttcatgctgttctacaaagaggcc ccttatcagaacgttacggaattcgacgggcaagacgcatgtggctccaacagctggact gtggtggacattgatccaccccagaggtccaacgaccccaagtcacagaaccaccctggg tggctgatgaggggtctcaaaccctggacccagtatgccatctttgtcaagaccttggtc accttttctgatgaacgccggacctacggggccaagagtgacatcatttatgtccagaca gatgccaccaatccctccgtccccctggacccaatctcggtgtctaattcctcctctcag attattttgaaatggaagcccccctccgaccccaatggcaacatcacccactacttagtc ttctgggagaggcaggaggaagacagtgagctgtacgagttggattattgcctcaaaggg ctgaagctgccctcccgcacctggtctccaccatttgagtctgaggattcccagaaacac aatcagagtgaatatgaggagtccgctggtgaatgttgctcctgcccaaagaccgactcc cagattctgaaggagctggaggagtcctcattcaggaagacgtttgaggattatctgcac aatgtggtgtttgtccccagagaaacctctccaggcacaggtgccgaggacactaggcca tctcggaaacgcaggtcccttggcgccattgggaacgtaactgcagctgcccccacggtc gcagccttcctcaacaccacctcaaccagcgtgcccaccagccccgaggagcaccggcct ttcgaaaaagtggtgaacaaagagtcgctggtcatctccggcctgcgccacttcacaggc tatcgcatcgagctgcaggcctgcaaccaggacactcctgaggagcggtgtagtgtggca gcctatgtcagcgccaggaccatgcccgaagccaaggcagatgatattgtcggccccgtg acccacgaggtcttcgagaacaacattgttcacttgatgtggcaggagccgaaggaaccc aacggcctgatcgtgctgtacgaagtgagttaccggcgatatggcgatgaggaactgcac ctctgcgtctctcgcaagcattacgctctggagcggggctgccggctgcgtgggctgtcg ccggggaactacagcgtgcgggtccgggccacctccctggcgggcaatggctcctggaca gaagccacttatttctatgtgacagactatttagacgtcccatcaaatattgcaaaaatt atcatcggccccctcatctttgtcttcctcttcagtgttgtgattggaagtatttatcta ttcttgagaaaacggcagccggatgggcctctgggaccgctgtatgcatcttcaaaccct gagtacctcagtgccagtgatgtgtttccgtgctctgtgtacgtgccggacgagtgggag gtgccccgagagaagatcaccctcctccgagagctgggccagggctcctttggcatggtg tacgagggcaacgccaaggacatcgtcaagggtgagccggagacccgggtggcggtgaag acagtcaacgagtcggccagtctccgagagcggatcgagttcctcaatgaggcatcggtc atgaagggcttcacctgccatcatgtggtgcgcctcctgggggtggtgtccaagggccag ccgacactggtggtgatggagctgatggcccacggggacctgaaaagctacctccgttcc ctgcggccagaggctgagaacaatcccggccgccctcccccaaccctgcaagagatgatc cagatggcagcagagattgcagatgggatggcatacctgaatgccaagaagtttgtgcat cgagacctggcggccaggaactgcatggtggcccatgattttactgtcaagattggagac tttggaatgaccagagacatctatgaaacggattactaccggaaagggggcaagggactg ctccccgtaaggtggatggcaccagaatccctgaaggatggggtctttaccacttcttcc gatatgtggtcctttggcgtggtcctttgggaaatcaccagcctggccgaacagccttac cagggcctgtctaatgagcaggtgttgaaatttgtcatggatggagggtatctggatcaa cctgacaactgtccagagagagtcaccgacctgatgcgcatgtgctggcagttcaacccc aagatgcggccgaccttcctagacatcgtcaacctgctcaaggacgacctgcaccccagc ttcccggaagtttccttcttccatagcgatgagaacaaggctcccgaggccgaggagctg gagatggagttcgaggacatggagagtgtccctctggaccggtcctcacactgtcagagg gaggaggcggggggccgggagggggggtcctcgctgggcctcaagcggaactacgaggag cacatcccttacacccacatgaacgggggcaagaagaacgggcggatcctgaccctgcct cggtccaacccctcctaa

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