Thermochaetoides thermophila: CTHT_0060690
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Entry
CTHT_0060690 CDS
T03100
Name
(RefSeq) putative histidine biosynthesis trifunctional protein
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
cthr
Thermochaetoides thermophila
Pathway
cthr00340
Histidine metabolism
cthr01100
Metabolic pathways
cthr01110
Biosynthesis of secondary metabolites
cthr01230
Biosynthesis of amino acids
Module
cthr_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
cthr00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
CTHT_0060690
Enzymes [BR:
cthr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
CTHT_0060690
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
CTHT_0060690
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
CTHT_0060690
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Histidinol_dh
PRA-CH
PRA-PH
Motif
Other DBs
NCBI-GeneID:
18260107
NCBI-ProteinID:
XP_006696385
UniProt:
G0SF38
LinkDB
All DBs
Position
Unknown
AA seq
869 aa
AA seq
DB search
METTLPLPFAVSVNVPPGLAGEKEGLTREEVSCLGVVFFEVTPQTLEKLLRFLAQHNTEF
QAFFDVTRLQSRDDVVTLLDAGARRVFVRPEQLADFAEFGARVAPVVYGSNPSQLASATE
HGLLVSGFDLAASEAVQFAKEAKAKKIQNLFVKPVPGTDLASLVNYTAQFDAIPILPSTG
LSSKPEDGKLAVSKILASTWKSDRPDGLIPTVVCDEHDTALGLVYSSEESVGEALKTQTG
VYQSRKRGLWYKGATSGDTQELVRISLDCDNDALKFVVRQKGRFCHLPQSGCFGDLRGIA
KLEKTLFSRKQSAPEGSYTARLFNDEKLLRAKIMEEAEELCDAKTPEEVAFEAADLIYFA
LTKAVSAGVTLADIERSLDAKSFKVKRRTGDAKGKWAEKEGIKPATPAPAPAPAPAPAPE
PKKEPASDKIKMQTYDLAKVSKEELYEALKRPSQKSYDAILKIITPIIEDVRKNGDKAVL
SYTHKFEKATSLTSPVLKAPFSESMMQLPPETIQAIDISFENIRKFHAAQKEDKPLQVET
MPGVLCSRFSRPIEAVGLYVPGGTAVLPSTALMLGVPAMVAGCKRIVLATPPRADGTVTP
EVVYVAHKVGAEAIILAGGAQAVAAMAYGTESIAKVDKILGPGNQFVTAAKMFVSNDTNA
NVSIDMPAGPSEVLVIADSDANPAFVASDLLSQAEHGVDSQVVLIAVDLSDERLAEIEEE
LHRQAMELPRVEIVKGSIAHSLTVRVKTVDEAMEISNMYAPEHLILQLRDAEKVVEKVMN
AGSVFVGQWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLASFVKHITSSNLTAEGLRNVG
EAVMRLAKVEELEAHRRAVSIRLDYMNRN
NT seq
2610 nt
NT seq
+upstream
nt +downstream
nt
atggagacgacactccccctccccttcgccgtcagcgtcaatgtgccccccggactggcc
ggcgagaaggagggtctaacgcgcgaggaggtctcgtgcctgggcgtcgtcttcttcgag
gtgacgccccagaccctcgaaaaactgttgcgcttcctggcccagcacaacaccgagttc
caagctttcttcgatgtcacacgcctccagtcccgcgacgacgtcgtcaccctgctcgat
gccggcgcccgcagggtgtttgtgcgccccgagcaactagccgactttgctgagttcggt
gcccgtgttgctccagtcgtctacggctccaaccccagccagctagcttcggctactgaa
cacggtctgctcgtctctggcttcgacctggctgccagcgaggccgtccagttcgctaag
gaggccaaggccaagaagatccagaacctctttgtgaagcccgtgcccgggaccgacctc
gccagcctcgtcaattacaccgcccagttcgacgccatccccatcctgccctcgaccggt
ctgtcgagcaagccggaggacggcaagctggccgtatccaagatcctcgcgtcgacatgg
aagtcggaccgcccggatgggctgatcccgactgttgtctgcgacgagcacgacaccgcc
ctgggcctggtctacagcagcgaggagagcgttggcgaggcccttaaaacacagaccggc
gtctaccagagccggaagcgtggtctgtggtataaaggtgccacgtcaggtgacacccag
gagctggtccggatatcactggattgtgataatgacgcgctcaagttcgtcgtccgtcag
aagggtcgcttctgccacctgccgcagtccggttgcttcggcgacctgcggggtatcgct
aagctggagaagacccttttttcaaggaaacagtctgctccggagggctcgtacaccgct
cgtctgttcaatgacgagaagctcctgcgagccaagatcatggaggaggccgaggagctg
tgcgatgccaagacccctgaagaggttgccttcgaggcggccgacctcatctactttgct
cttaccaaggccgtcagcgccggtgtgactctggccgacatcgagaggagtctcgatgcc
aagagtttcaaggtgaagcgcaggacaggcgacgccaagggcaagtgggctgagaaagag
ggcatcaagcccgccactccggctccggccccggctccggctccggctcctgcgcctgag
cccaagaaggaaccggcctctgacaagatcaagatgcagacgtacgatttagccaaggtc
tccaaggaagagctctacgaggcgctcaagcgcccctcacaaaagtcctacgacgccatc
cttaagatcatcacccccatcatcgaagatgtccgcaagaacggcgacaaagccgtcctc
tcttacacacacaaattcgagaaggcgacctccctgacttcccccgtcctcaaggccccc
ttctcagagagtatgatgcaacttccccccgaaaccatccaagccatcgacatctccttc
gagaacattcgcaaattccacgccgcccaaaaagaggacaagcccctccaggtcgagacc
atgcctggcgtcctctgcagccgcttctcccgccccatcgaggccgtaggcctctacgtg
ccaggcggcaccgccgtgctgcccagcacggccctcatgctcggcgtccccgccatggtg
gccggctgcaagcgcatcgtgcttgccacgccgccgcgcgccgatggcacggtgactccc
gaagtggtctacgtcgcgcacaaggtcggcgcggaggcgattattttggcgggtggcgcc
caggccgtggcggccatggcctacggcacggagagcatcgcgaaggtggacaagattctg
ggtcccggcaaccagttcgttaccgcggccaagatgttcgtcagcaacgataccaacgcc
aacgtgagcatcgacatgccagccggcccgtctgaggtgcttgtcattgcggacagcgat
gccaacccggcgtttgtggcgtccgacttgctctcgcaggcggagcatggcgtggatagt
caggtggtgttgattgcggtggatctatcggacgagaggctcgcggagattgaggaggag
ctgcacaggcaggcgatggagttgccgcgcgtggagattgtcaaggggtcgattgcgcac
tcgttgacggttagggtgaagactgtggatgaggcgatggagattagtaatatgtacgcg
ccggagcatttgattttgcagttgagggatgcggagaaggtggttgagaaggtgatgaat
gcgggaagtgttttcgtgggccagtggacgcccgagagcgtgggggattactcagctggt
gttaaccattctttgccaacctacggctacgccaagcaatactctggcgtcaacctcgcc
tcctttgtcaagcatatcaccagctccaacctcactgccgagggactgcggaatgttggc
gaggcggtcatgcgcctggctaaggttgaggagctagaggctcacaggagggctgtcagc
atccggttggactatatgaaccggaattag
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