Corynebacterium variabile: CVAR_2738
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Entry
CVAR_2738 CDS
T01594
Symbol
hemD
Name
(GenBank) uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cva
Corynebacterium variabile
Pathway
cva00860
Porphyrin metabolism
cva01100
Metabolic pathways
cva01110
Biosynthesis of secondary metabolites
cva01120
Microbial metabolism in diverse environments
cva01240
Biosynthesis of cofactors
Module
cva_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
cva_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cva00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CVAR_2738 (hemD)
Enzymes [BR:
cva01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CVAR_2738 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CVAR_2738 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AEK38077
UniProt:
G0HHX3
LinkDB
All DBs
Position
complement(3076743..3078557)
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AA seq
604 aa
AA seq
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MTSAGNALGYGRVLFVGAGPGNPELLTVRARDILEHTVHAWVDPAVPENVRSLIADAEPV
SAAKLDAAEQEWQAENEAAKEAGSRRRPARPTHVTAAEIVLAVPGGDSVNAAATRTSVDL
PDSPCGRAGATGPDLTVPDLTAQSLAADMVEIIHSGVNVVRLVAGNPVDDPAVLRELREV
AALGAEFEVIPGMTGASALPAYNGIPTGDGYTAVDLRGGLPGVDWSAVAAAPKPLILTVA
PTDLAPVARELKGHGVPGSTPATVTVHATTRKQRSWDVTLDTLKSVVAASGPLAKEGELP
EHLVVTLGAAASGRSKYSWWESRALYGWNVLVPRAKAQAGPMSTRLASHGAIPIEVPTIS
MEPPRSPAQMERAVKGLVDGRYQWIVFTSVNAVNAVWEKLREFGLDARALAGVSVAAVGE
KTAQAVRDLGITPELLPKAKARNAAGLVEVFPPYDEDLDPVDRVLLPRADIATDTLVDGL
IDLGWSVEDVVAYRTVRAAPPSQDIRDMIKSGGFDAVCFTSSSTVKNLVGIAGKPHTRTI
IACIGPMAAKTAEEHGLRVDVMPEVAGVPELVDALAEHVAALRAADQLPPPRKRRRRRRT
VPAE
NT seq
1815 nt
NT seq
+upstream
nt +downstream
nt
atgacctctgccggtaatgccctcggatacggacgtgtacttttcgtcggtgccggacca
ggcaaccccgaactgctgaccgtccgtgcccgcgacattctcgagcacacggtccatgcc
tgggtcgaccctgccgtgcccgagaacgtccgctcactcatcgcggacgccgagccggtc
tccgccgccaagctcgacgcggcggaacaggagtggcaggccgagaacgaggcggccaag
gaagccggcagccgtcggcgtcccgcccgacccacccacgtcaccgccgccgagatcgtc
ctcgcggtccccggcggggattcggtcaacgccgcggcaacccgcacctccgtcgacctg
ccggactcgccgtgcggtcgcgccggtgccaccggtcccgacctgacggtcccggacctc
accgcccagagcctcgccgccgacatggtcgagataatccacagcggcgtcaacgtggta
cgtctcgtggcaggtaacccggtcgatgacccggctgtgctgcgtgagctgcgtgaggtc
gccgccctcggcgccgagttcgaggtcatcccggggatgaccggcgcgtcggcgctgccc
gcctacaacggcatccccaccggtgacggctacaccgccgtcgacctgcgtggcggactg
cccggtgtcgactggtccgccgtcgccgccgccccgaagccgctgatcctcacggtcgcc
cccaccgacctcgccccggtcgcccgggagctcaagggacacggcgtccccggatcgacc
ccggcgaccgtcaccgtccacgcgacgacccgcaagcagcgctcctgggatgtcaccctc
gacaccctgaagtcggttgtcgccgcctccggtccgctggccaaggagggtgagctgccg
gagcacctggtcgtcaccctcggcgccgcggcgtccggccggtcgaagtactcctggtgg
gaaagccgcgcgctctacggctggaacgtgctcgttccccgggcgaaggcccaggccggt
ccgatgagcacccggctggcgtcccacggtgccatcccgatcgaggtgccgacgatctcc
atggagccgccgcgcagtcccgcccagatggaacgtgctgtcaagggcctggtcgacggc
cgctaccagtggatcgtcttcacctcggtcaacgccgtcaacgcggtgtgggagaagctc
cgcgagttcggcctcgacgcccgcgccctggccggtgtctccgtcgccgccgtcggtgag
aagaccgcccaggccgtccgcgacctcggcatcacgccggaactgctgccgaaggcgaag
gcccgcaacgccgccggtctggtcgaggtctttccgccctacgacgaggatctggatccg
gtggaccgtgtgctgctgccgcgcgccgacatcgccaccgacaccctcgtcgacggtctc
atcgacctcggctggtcggtggaggacgtcgtcgcctaccgcaccgtgcgcgcggccccg
cccagccaggacatccgcgacatgatcaagtccggcggcttcgacgcggtgtgcttcacc
tcctcgtcgacggtgaagaacctcgtcggcatcgccggcaagccgcacacccgcacgatc
atcgcctgcatcggcccgatggcggcgaagaccgccgaggagcacgggctgcgcgtcgac
gtcatgcccgaggtcgccggtgtccccgagctggtggacgccctggccgagcacgtcgcc
gcgctgcgggccgctgaccagctgccgccgccgcgcaagcgtcgccgtcgccggcgcacc
gtgcctgccgagtag
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