Dipodomys ordii (Ord's kangaroo rat): 105986341
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Entry
105986341 CDS
T07834
Symbol
Sirt1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00760
Nicotinate and nicotinamide metabolism
dord01100
Metabolic pathways
dord04068
FoxO signaling pathway
dord04148
Efferocytosis
dord04152
AMPK signaling pathway
dord04211
Longevity regulating pathway
dord04213
Longevity regulating pathway - multiple species
dord04218
Cellular senescence
dord04310
Wnt signaling pathway
dord04922
Glucagon signaling pathway
dord04936
Alcoholic liver disease
dord05031
Amphetamine addiction
dord05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
105986341 (Sirt1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
105986341 (Sirt1)
04068 FoxO signaling pathway
105986341 (Sirt1)
04152 AMPK signaling pathway
105986341 (Sirt1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105986341 (Sirt1)
09143 Cell growth and death
04218 Cellular senescence
105986341 (Sirt1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105986341 (Sirt1)
09149 Aging
04211 Longevity regulating pathway
105986341 (Sirt1)
04213 Longevity regulating pathway - multiple species
105986341 (Sirt1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
105986341 (Sirt1)
09165 Substance dependence
05031 Amphetamine addiction
105986341 (Sirt1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
105986341 (Sirt1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
dord03036
]
105986341 (Sirt1)
03029 Mitochondrial biogenesis [BR:
dord03029
]
105986341 (Sirt1)
Enzymes [BR:
dord01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
105986341 (Sirt1)
Chromosome and associated proteins [BR:
dord03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
105986341 (Sirt1)
Mitochondrial biogenesis [BR:
dord03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
105986341 (Sirt1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
TPP_enzyme_M
DUF592
Motif
Other DBs
NCBI-GeneID:
105986341
NCBI-ProteinID:
XP_012872662
Ensembl:
ENSDORG00000005213
UniProt:
A0A1S3F9Y2
LinkDB
All DBs
Position
Unknown
AA seq
551 aa
AA seq
DB search
MIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQE
CKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQSMFDIDYFRKDPRPFFKF
AKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCL
ICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDE
VDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHR
LGGEYAKLCCNPVKLSEITEKPPRTQKELVNFLELPPTPLHISEESSSPERTSPPVSKVI
VTATKSKVDDLVISESKSCMEEKPQLVQTSIRNNESITVENSDLKDVGSSTEEKNDITSV
AETVRKCWPNRLPKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDILSSSSCGSNSD
SGTCQSPSLEEHMEDESEIEEFYNGLEDDADIPERDGGAGFGVDGNDQEPVNEAISMKQE
APDTSYPSNKS
NT seq
1656 nt
NT seq
+upstream
nt +downstream
nt
atgattggcacagatcctcgaacaattcttaaagatttattgccagaaacaattcctcca
cctgaattggatgatatgacactgtggcagattgtaattaatatcctttcagaaccacca
aaaaggaaaaaaagaaaagatattaatacaattgaagatgctgtgaaattactccaagag
tgcaaaaaaataattgttctaactggagctggggtatctgtttcatgtggaatacctgac
ttcagatcaagagatggtatttatgctcgccttgcagtagacttcccagatcttccagat
cctcaatctatgtttgatattgattatttcagaaaagatccaagaccattcttcaagttt
gcgaaggaaatatatcctggacaattccaaccatctctctgtcacaaattcatagccttg
tcagataaggaaggaaaactacttcgcaactatacgcagaatatagataccttggaacag
gttgcaggaatccaaaggataattcagtgtcatggttcctttgcaacagcatcttgcctg
atttgtaaatacaaagttgactgtgaagctgtacgaggagatatttttaatcaggtagtt
cctcgatgtcctaggtgtccagctgatgaaccacttgctatcatgaaaccggagattgtc
ttttttggtgaaaatttaccagaacagtttcacagagctatgaagtatgacaaagatgaa
gttgatctcctcattgttattgggtcttccctaaaagtaagaccagtagcactaattcca
agttccataccccatgaagtgcctcagatattaattaatagggaaccattgcctcatctg
cattttgatgtagagcttcttggagactgtgatgtcataattaatgaattgtgtcatagg
ttaggtggtgaatatgccaaactttgctgtaaccctgtaaaactttcagaaattactgaa
aaacctccacgaacacaaaaagagttggttaatttcttagagttaccaccaacaccactt
catatttcagaagagtcgagctcacctgaaagaacttcaccaccagtttctaaagtaatt
gttacagcaactaagagtaaagttgatgatttagtcatatctgaatcaaaaagttgtatg
gaagaaaaaccacaattagtacagacttctattaggaacaatgagagtattactgtggaa
aattcggatttaaaggatgtcggttctagtactgaagagaaaaatgatataacttcagtt
gctgaaacagtgagaaagtgttggcccaatagactcccaaaggaacagatcagtaagcgg
cttgatggtaatcagtatttgtttttaccaccaaatcgctacattttccatggggctgag
gtgtattcagactctgaagatgatatcctatcctctagttcatgtggcagtaacagtgat
agtggtacatgccagagtccaagtttagaagaacatatggaagatgaaagtgagattgaa
gaattctacaatggcttggaagatgatgctgatatcccagagcgagatggaggagctgga
ttcggggttgatggaaatgaccaagagccagttaatgaagctatatcaatgaaacaggaa
gcaccagatacgagctatccatcaaacaaatcataa
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