Dipodomys ordii (Ord's kangaroo rat): 105998714 Help Entry 105998714         CDS       T07834                                  Symbol Insr Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism dord  Dipodomys ordii (Ord's kangaroo rat) Pathway dord04010   MAPK signaling pathway dord04014   Ras signaling pathway dord04015   Rap1 signaling pathway dord04022   cGMP-PKG signaling pathway dord04066   HIF-1 signaling pathway dord04068   FoxO signaling pathway dord04072   Phospholipase D signaling pathway dord04150   mTOR signaling pathway dord04151   PI3K-Akt signaling pathway dord04152   AMPK signaling pathway dord04211   Longevity regulating pathway dord04213   Longevity regulating pathway - multiple species dord04520   Adherens junction dord04910   Insulin signaling pathway dord04913   Ovarian steroidogenesis dord04923   Regulation of lipolysis in adipocytes dord04930   Type II diabetes mellitus dord04931   Insulin resistance dord04932   Non-alcoholic fatty liver disease dord04960   Aldosterone-regulated sodium reabsorption dord05010   Alzheimer disease dord05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:dord00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105998714 (Insr)    04014 Ras signaling pathway     105998714 (Insr)    04015 Rap1 signaling pathway     105998714 (Insr)    04066 HIF-1 signaling pathway     105998714 (Insr)    04068 FoxO signaling pathway     105998714 (Insr)    04072 Phospholipase D signaling pathway     105998714 (Insr)    04022 cGMP-PKG signaling pathway     105998714 (Insr)    04151 PI3K-Akt signaling pathway     105998714 (Insr)    04152 AMPK signaling pathway     105998714 (Insr)    04150 mTOR signaling pathway     105998714 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     105998714 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105998714 (Insr)    04923 Regulation of lipolysis in adipocytes     105998714 (Insr)    04913 Ovarian steroidogenesis     105998714 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     105998714 (Insr)   09149 Aging    04211 Longevity regulating pathway     105998714 (Insr)    04213 Longevity regulating pathway - multiple species     105998714 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     105998714 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     105998714 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105998714 (Insr)    04932 Non-alcoholic fatty liver disease     105998714 (Insr)    04931 Insulin resistance     105998714 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dord01001]     105998714 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:dord04090]     105998714 (Insr) Enzymes [BR:dord01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      105998714 (Insr) Protein kinases [BR:dord01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    105998714 (Insr) CD molecules [BR:dord04090]  Proteins   105998714 (Insr) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  105998714 NCBI-ProteinID:  XP_012888957 Ensembl:  ENSDORG00000014700 UniProt:  A0A1S3GLS9 LinkDB All DBs Position Unknown AA seq 1140 aa AA seqDB search MDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRYLSFPKLIMITDYLLLFRVYGLE SLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLAT IDWSRILDSVEDNYIVLNKDDKEECGDICPGTGKGKANCPATVINGHFVERCWTHSHCQK VCPTICKSHGCTADGLCCHSECLGNCSAPDDPTKCVACRNFYLEGRCVPTCPPPYYHFQD WRCVNFSFCLDLHNKCKNSRRQGCHQYVIHDNKCIPECPSGYTMNSTNLMCTPCLGPCPK ICHLLEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKI RRSYALVSLSFFRKLRLIRGETLEVGNYSFYALDNQNLRQLWDWSKHNLTIINGKLFFHY NPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRTSYDKIMLKWE PYWPPDFRDLLGFMLFYKEAKASSGNGVEDSRPSRKRRSLGDVVNVTMMPPVIPIFPNVS STVVPTTQEPPRPVEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVSART MPEAKADDIVGPVTHEIFENNVVHLTWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKH FALEQGCRLRGLPPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNLAKIIIGPLIF VFLFSGVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRDKIT LLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNEAASLRERIEFLNEASVMKGFTCH HVVRLLGVVSKGQPTLVVMELMAQGDLKSYLRSLRPDAENNPGRPPPTLQEMIQMAGEIA DGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYEMDYYRKGGKGLLPVRWMA PESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPER VTNLMHMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKGPENEELEMEFEGD MENVPLDRSSHCQREEAGGREGGVSSLGLKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS NT seq 3423 nt NT seq  +upstreamnt  +downstreamnt atggatattcggaataacctcaccaggttgcatgagttggagaattgctcagtcatcgaa ggccatttgcagattcttctgatgttcaaaacgaggcctgaagatttccgttacctcagt ttccccaaactcatcatgatcactgattacttgctgctcttccgggtgtatgggctggag agtctgaaagatctgtttcccaatctcacggtcatccggggctcccgtctcttcttcaat tatgccctggtgatctttgagatggttcatctcaaggaactcggcctgtacaacctgatg aacatcacccggggctctgtccgcatcgagaagaacaatgagctctgttatttggccacc atcgactggtcccgaatcctggactctgtggaagacaattatattgtcctgaacaaggat gacaaggaagagtgtggtgacatttgtcctggcactgggaagggcaaagccaactgccct gccaccgtcatcaatgggcattttgttgagcgatgctggactcacagccattgccagaaa gtgtgcccgaccatctgcaagtcgcacggctgcacggctgacggcctgtgctgtcacagc gagtgtctggggaactgctcagcgcccgacgaccccaccaagtgcgtggcctgccgcaac ttctacctggaaggccgctgcgtgcccacctgcccgccgccctactaccacttccaagac tggcgctgtgtcaacttcagcttctgcctggacctgcacaacaagtgcaagaactcacgg aggcagggctgtcaccagtacgtcatccacgacaacaagtgcatccccgagtgcccctcc gggtacacgatgaactccaccaacttgatgtgtaccccatgcctggggccttgtcccaag atctgtcacctcctggaaggagagaagacaattgactcagtgacctcagcccaggagctt cgaggctgtacggtggttaacggcagcctgattatcaatatccgaggaggcaacaaccta gcggctgaactagaggccaaccttggcctcattgaggaaatatccgggtacctaaaaatc cgacgctcctacgctctggtctctctttccttcttccggaagctgcgtttgattcgaggg gagaccttggaagtggggaattactctttctatgctctggacaaccagaacctaaggcaa ctctgggactggagcaagcacaacctcaccatcatcaatgggaaactcttcttccactat aaccccaaactttgcttgtccgaaatccacaagatggaagaagtttctggaaccaaggga cgtcaggagagaaatgacattgccctaaagaccaatggagaccaggcctcctgtgaaaac gaattacttaagttttccttcatccgcacatcatatgacaagattatgctgaaatgggag ccctactggccccccgatttccgagacctcttggggttcatgctcttctacaaagaggca aaagcctcttcaggcaatggtgtagaagattctaggccatccaggaagcgcaggtctctc ggggacgtggtgaacgtgaccatgatgccgcctgtcatcccgattttccccaacgtctcc tccaccgtggtgcccaccacccaggagccaccccggcccgtcgagaaagttgtgaacaag gagtcgctggtcatctcgggcctgcgtcacttcaccggctaccgcatcgagttgcaggcc tgcaaccaagacgccccggaggagaggtgcagcgtggccgcctatgtcagcgcccggacc atgcctgaagccaaggcggatgacatcgtcggccctgtgacccacgaaatcttcgagaac aacgttgtgcacttgacctggcaggagcccaaggagcccaacggcctgatcgtgctgtat gaagtcagctaccggcgctacggcgatgaggagcttcacctctgcgtctccagaaagcat tttgccctggagcagggatgccggctgcgagggctgccccctggcaactacagtgtgcgc atccgggccacctcattggccggcaacggctcctggaccgaacctacttatttctacgtg acagattatttagatgtcccatccaaccttgcgaaaatcatcatcggcccgctcatcttc gtcttcctcttcagcggtgtgatcggaagcatttacctgttcctcagaaagaggcagccg gatgggccaatgggaccactatatgcttcttcaaatcctgagtatctcagtgccagtgat gtttttccatgttctgtgtacgtgccggacgagtgggaagtgccccgggacaagatcacc ctcctgcgggagctgggccagggctccttcggtatggtgtacgagggcaatgccaaggac atcatcaagggcgaggcggagacccgtgtggcggtgaagacggtcaatgaggcggccagt ctgcgggagcgcattgagttcctcaacgaggcttcggtcatgaagggcttcacctgtcac cacgtggtccgcctcctgggcgtggtgtccaagggccagcccacactggtggtgatggaa ctgatggctcaaggagacctgaagagctacctccgatctctgaggccagacgccgagaat aacccgggtcgaccaccccctacgctgcaagagatgattcagatggcaggagagattgct gacggcatggcctacctgaatgccaagaagtttgtgcaccgagacctggctgcacgaaac tgcatggttgcccacgattttactgtcaaaattggagactttggaatgaccagagacatc tacgaaatggattactaccggaaggggggcaagggcctgctacctgtgcggtggatggca cccgaatccctgaaggatggggtcttcactgcttcctcagatatgtggtcctttggtgtg gtcctctgggaaatcaccagtttagccgaacagccttaccaaggcctgtctaatgaacag gtgttgaaattcgtcatggatggagggtacttagatcagcctgacaattgtcctgagaga gttaccaatttgatgcacatgtgttggcaattcaaccccaaaatgcgccccaccttcctg gagatcgtcaacctgctcaaggatgacctgcaccctagctttccagaagtttcctttttc cacagcgaggagaacaaggggccggagaatgaggagctggagatggagtttgagggggat atggaaaatgtacccttggatcggtcctcacactgtcagagggaagaggccgggggccgg gagggcggagtgtcctccctagggttgaagcggagttatgaagagcacatcccttacacc cacatgaatggaggcaagaagaatgggaggattctgactcttcccagatcaaatccttcc taa

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