Desmodus rotundus (common vampire bat): 112297707
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Entry
112297707 CDS
T05907
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
dro
Desmodus rotundus (common vampire bat)
Pathway
dro04148
Efferocytosis
dro04330
Notch signaling pathway
dro04668
TNF signaling pathway
dro05010
Alzheimer disease
dro05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
dro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
112297707 (ADAM17)
04668 TNF signaling pathway
112297707 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
112297707 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
112297707 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
112297707 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
dro01002
]
112297707 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
dro04090
]
112297707 (ADAM17)
Enzymes [BR:
dro01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
112297707 (ADAM17)
Peptidases and inhibitors [BR:
dro01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
112297707 (ADAM17)
CD molecules [BR:
dro04090
]
Proteins
112297707 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Reprolysin_2
Reprolysin_5
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
112297707
NCBI-ProteinID:
XP_024408218
LinkDB
All DBs
Position
Unknown
AA seq
827 aa
AA seq
DB search
MRQCLLFLTSLVPFVLAPRPPGEPSFGSPQRLEELDSLLSDYDILSQSSIRQHSVRKRDV
QASTHLETLLTFSALKRHFKLYLTSSTERFSQDFKVVVVDGKDESEHSVRWQDFFRGHVV
GEPNSRVLAHIGDDDVTIRINTDAAEYTVEPLWRLVNDTKDKRMLVYKSEDIKNVSRLQS
SKVCGYIKAENEDFLPEGLIDRQPRDERVPRAKRRAELHSLKNTCKLLVVADHRFYRHMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGERHYNM
AKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPTGRKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKFVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNSDTCCNSDCTLKRGVQCSDRNSPCCKNCRFETAQKKCQEAINA
TCKGVSHCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQHLESCACNETDNSC
KVCCRDPSGRCVPYVDAEQRNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLVVWIPLSVLVHCVDKKLDKQYESLSLFHPSNVEMLSSMD
SASVRIIKPFPGPQTPGRLQPLQAVPVPPLVPTAPKLDHPRMDTIQEDPSTDSHVDEDGF
EKDPFPSSSTAAKSFEDLTDHPVTRSEKASSFKLQRQSRVDSKETEC
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagtgtctcctcttcctgaccagcttagttcctttcgtgctggcgccgcgacct
ccgggggagccgagcttcggctccccgcagcgactcgaggagctcgattctttgctgtca
gactacgacatcctctctcagtccagcatccgccagcactcagtgaggaagagagacgta
caggcttcaacacacctggaaacactgctgaccttttcagcgctgaaaaggcattttaaa
ttatacttgacatcgagtactgaacgcttttcccaagatttcaaagtcgtggtggtggac
gggaaagatgagagcgagcacagcgtcaggtggcaggacttcttccgcgggcacgtggtc
ggtgagcctaactctcgggttctagcccatataggagacgacgatgtgacaatacggatc
aacacagacgcggcggaatataccgtggagccactttggagactagttaatgatactaaa
gacaaaagaatgttggtttataaatctgaagatatcaagaatgtttcacgtttacagtct
tcaaaagtgtgtggttacataaaagcggaaaatgaagatttccttccggaagggctgata
gacagacagccccgtgacgagcgtgttcctcgggcgaagagaagagccgagcttcactcc
ctgaagaacacgtgcaaactgctggtggtggcagaccaccgcttttacagacacatgggc
cgcggggaggagagcaccaccaccaactacctaatagagctgatcgacagggtcgatgac
atctatcggaacacttcatgggacaacgcaggctttaaaggctacgggatacagatagag
cagattcgcattctcaagtctccacaagaggtaaaacctggtgaaaggcactataatatg
gcaaaaagttatccaaatgaagaaaaggatgcttgggatgtgaagatgttgctcgagcaa
tttagctttgatatagctgaagaggcatctaaggtctgtctagcacaccttttcacgtac
caggatttcgacatggggactctcggactagcgtacgttggctctcccagagcaaacagt
cacggaggcgtctgtccgaaggcgtattacagcccaaccggaaggaagaatatctatttg
aatagtggcttgaccagcacaaaaaattatggtaaaaccattcttacaaaggaagcggac
ctggttacaactcatgaattggggcacaatttcggagcagagcacgatccggatggtcta
gcagagtgcgctccgaacgaggaccagggagggaagttcgtgatgtaccccatcgctgtg
agtggggatcacgagaacaacaagatgttttccaactgcagcaagcagtccatctacaag
accatcgagagcaaggcccaggagtgcttccaggagcgcagcaacaaggtgtgcgggaac
tccagggtggacgaaggggaggagtgcgaccccggcatcatgtacctgaacagcgacacc
tgctgcaacagcgactgcacgctgaagaggggtgtgcagtgcagtgacaggaacagtccc
tgctgtaaaaactgccggttcgagactgcccagaagaagtgccaggaggccatcaacgcc
acctgcaaaggcgtgtctcactgcacaggtaacagcagcgagtgcccccctcccgggaat
gctgaggatgacaccgtgtgcttggacctgggcaagtgcaaggacgggaagtgcatcccc
ttctgtgagagggagcagcatctggagtcctgtgcgtgcaatgagacggacaactcatgc
aaggtgtgctgccgggacccctcgggccgctgcgtgccctatgtcgatgctgagcagagg
aacttgtttttgaggaaagggaagccctgtacagtggggttttgtgacatgaatggcaaa
tgtgagaaacgggtccaggacgtcatcgagcgcttttgggacttcatcgaccagctgagc
atcaatactttcgggaagtttctggcagacaacatcgtaggttccgtcctggttttctcc
ttggtagtctggattcctctcagcgtgctcgtccactgcgtggataagaaactggacaag
cagtacgagtctctgtctctgtttcaccccagtaacgtcgaaatgctcagcagcatggac
tcagcgtcggttcgcatcatcaagccctttcctgggccgcagacccctggtcgcctgcag
ccgctgcaggccgtccccgtgccgccgctggtgcctacggccccaaagctggaccacccg
cggatggacacgatccaggaggaccccagcacggactcacacgtggacgaggacggcttc
gagaaagaccccttccccagcagcagcacggccgccaagtcctttgaggacctcaccgac
cacccggtcaccaggagcgagaaggcctcgtcatttaagctgcagcggcagagtcgtgtc
gacagcaaagaaaccgagtgctag
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