Equus asinus (ass): 106835514
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Entry
106835514 CDS
T04645
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
eai
Equus asinus (ass)
Pathway
eai00010
Glycolysis / Gluconeogenesis
eai00020
Citrate cycle (TCA cycle)
eai00620
Pyruvate metabolism
eai00785
Lipoic acid metabolism
eai01100
Metabolic pathways
eai01200
Carbon metabolism
eai01210
2-Oxocarboxylic acid metabolism
eai04066
HIF-1 signaling pathway
eai04922
Glucagon signaling pathway
eai05230
Central carbon metabolism in cancer
eai05415
Diabetic cardiomyopathy
Module
eai_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
106835514 (PDHA1)
00020 Citrate cycle (TCA cycle)
106835514 (PDHA1)
00620 Pyruvate metabolism
106835514 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
106835514 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
106835514 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
106835514 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
106835514 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
106835514 (PDHA1)
Enzymes [BR:
eai01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
106835514 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
106835514
NCBI-ProteinID:
XP_044619413
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All DBs
Position
X:complement(60139393..60158634)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRSFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYFGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGHHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtttcccgtgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcctcccgtagttttgcaaacgatgctacgtttgaaattaagaaa
tgtgatctacaccggctggaagagggccctcctgtcacgacagtgctcaccagggaggac
gggctcagatactacaggatgatgcagactgtccgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcatcaaccccacagaccatcttatcacagcctatcgggct
cacggctttacctttactcgtgggctgtctgtccgagaaattctcgccgagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtatgccaagaacttc
tacgggggcaatggcattgtcggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtattttggaaaagatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatattcgaagcttacaacatggcagctttgtggaaattgccttgtattttc
atctgtgaaaataaccgctatggaatgggaacttctgttgagagagcagcagccagcact
gattattacaagagaggtgacttcatccctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggcgacaaggtttgcagctgcctattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
tatcgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggatagaatggtgaacagcaaccttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgccgcccagtttgccacagctgatcccgaaccacct
ttggaagaactaggccatcacatctacagcagtgatccgccttttgaagttcgcggtgca
aatcagtggatcaagtttaagtccatcagttaa
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