Equus asinus (ass): 106844524 Help Entry 106844524         CDS       T04645                                  Symbol INSR Name (RefSeq) insulin receptor isoform X2   KO K04527   insulin receptor [EC:2.7.10.1] Organism eai  Equus asinus (ass) Pathway eai04010   MAPK signaling pathway eai04014   Ras signaling pathway eai04015   Rap1 signaling pathway eai04022   cGMP-PKG signaling pathway eai04066   HIF-1 signaling pathway eai04068   FoxO signaling pathway eai04072   Phospholipase D signaling pathway eai04150   mTOR signaling pathway eai04151   PI3K-Akt signaling pathway eai04152   AMPK signaling pathway eai04211   Longevity regulating pathway eai04213   Longevity regulating pathway - multiple species eai04520   Adherens junction eai04910   Insulin signaling pathway eai04913   Ovarian steroidogenesis eai04923   Regulation of lipolysis in adipocytes eai04930   Type II diabetes mellitus eai04931   Insulin resistance eai04932   Non-alcoholic fatty liver disease eai04960   Aldosterone-regulated sodium reabsorption eai05010   Alzheimer disease eai05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:eai00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     106844524 (INSR)    04014 Ras signaling pathway     106844524 (INSR)    04015 Rap1 signaling pathway     106844524 (INSR)    04066 HIF-1 signaling pathway     106844524 (INSR)    04068 FoxO signaling pathway     106844524 (INSR)    04072 Phospholipase D signaling pathway     106844524 (INSR)    04022 cGMP-PKG signaling pathway     106844524 (INSR)    04151 PI3K-Akt signaling pathway     106844524 (INSR)    04152 AMPK signaling pathway     106844524 (INSR)    04150 mTOR signaling pathway     106844524 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     106844524 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     106844524 (INSR)    04923 Regulation of lipolysis in adipocytes     106844524 (INSR)    04913 Ovarian steroidogenesis     106844524 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     106844524 (INSR)   09149 Aging    04211 Longevity regulating pathway     106844524 (INSR)    04213 Longevity regulating pathway - multiple species     106844524 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     106844524 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     106844524 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     106844524 (INSR)    04932 Non-alcoholic fatty liver disease     106844524 (INSR)    04931 Insulin resistance     106844524 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:eai01001]     106844524 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:eai04090]     106844524 (INSR) Enzymes [BR:eai01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      106844524 (INSR) Protein kinases [BR:eai01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    106844524 (INSR) CD molecules [BR:eai04090]  Proteins   106844524 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  106844524 NCBI-ProteinID:  XP_014717501 LinkDB All DBs Position 20:complement(5070957..5198602) Genome browser AA seq 1381 aa AA seqDB search MGAGGRRGAAAAPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTADGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLTFSHIRTSSDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTNATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQEEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKSSSGPGAEDTRPSRKRRALADVGNVTVAVPTVPGF PNTSSTSTPTSSEERRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYYVPSNIAKIIIGP LIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE KITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGF TCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMVQMAA EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR WMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNC PERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEF EDMENVPLDRSSHSQREEAGGRDAGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNP S NT seq 4146 nt NT seq  +upstreamnt  +downstreamnt atgggcgcagggggccgacggggggcggcggccgcgccgctcctggtggccgtggccgcg ctgctggtgggcgccgcgggccacctgtaccccggagaggtgtgccccggcatggatatc cggaacaacctcacgaggctgcacgagctggccaactgctccgtcattgaaggacacttg cagattctgttgatgtttaaaacgaggcctgaggatttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtgtacgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctctcgcctcttcttcaactacgcgctg gtcatcttcgagatggttcacctgaaggagcttggcctctacaacctgatgaacatcacc cgcggctccgtccgcatcgagaagaacaacgagctgtgctacctggccaccattgactgg tcgcgcattctggactcggtggaagataattacatcgtgctgaacaaggacgacaatgag gagtgcggggacatttgtccaggcaccgccaagggcaagaccaactgccccgctactgtc atcaatggacagtttgttgagcggtgctggacgcacagccattgccagaaagtttgcccg accatctgtaagtcacacggctgcaccgcggacggcctctgctgccacagcgagtgttta ggcaactgctctgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg gacggcaggtgtgtggagacctgcccgcccccgtactatcacttccaagactggcgctgt gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactcccgaaggcagggc tgccatcagtacgtcattcacaacaacaagtgcatccctgagtgtccctctgggtacacg atgaattccagcaacttgatgtgtaccccgtgcctgggtccctgtcccaaggtgtgccac ctcctggaaggcgagaagaccatcgactcggtgacgtccgcccaggagctccgaggctgc acggtcatcaacgggagcctgatcatcaacatccgagggggcaacaacctggcagctgag ctagaggccaacctcggactcattgaagaaatttcagggtatctgaaaatccgccggtcc tacgctctcgtgtcgctttccttcttccggaagttacgcctaattcggggagagaccttg gaaatcgggaactactcattctacgccttggacaaccagaacctgaggcagctatgggac tggagcaagcacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa ctctgcttgtcggaaattcacaagatggaggaagtttcaggaaccaaagggcgccaggag aggaacgacatcgccctgaagaccaacggggaccaggcatcctgtgaaaatgagttactt acattttctcacattcggacatcttctgacaagatcttgctgaaatgggagccgtattgg ccccccgacttccgagacctcttgggcttcatgctcttctataaagaggccccttatcag aacgtgacggagttcgatgggcaggatgcgtgtggctccaacagctggacggtagtggac attgacccacctctgaggtccaacgaccccaagtcacagaaccaccctgggtggctgatg cgaggtctcaaaccctggacccagtacgccatctttgtcaagaccttggtcaccttttct gatgaacgccggacatacggggccaagagcgacatcatctatgtccagacaaatgccacg aacccgtctgtccccctggatcccatctccgtttctaattcctcgtcccagattattctg aagtggaagcccccctctgaccccaatgggaacatcacacactacctggttttctgggag aggcaggaggaagacagcgagctgtacgagttggattattgcctcaaaggcttgaagctg ccctccaggacctggtctccaccgtttgagtctgaggggtcccagaagcacaatcagagt gagtacgaggagtctgccggcgaatgctgctcctgcccgaagaccgactcccagatcctg aaggagctggaggagtcctcgttcaggaagacgttcgaggactatctgcacaatgtggtt tttgtccccagaaaatcctcttcaggccctggtgccgaggacactagaccgtctcggaaa cgcagggcgcttgctgatgtcgggaatgtgacggtggccgtgcccacggttccgggtttc cctaatacctcctccaccagcacgcccacgagctcagaggagcgcagacccttcgagaaa gtggtgaacaaggagtcgctggtcatctccggcctgcgccattttaccggctatcgcatc gagcttcaggcttgcaaccaagattcccccgaagagaggtgcagtgtggctgcctatgtc agtgccaggaccatgcccgaagccaaggcggacgacatcgttggccctgtgactcacgaa atcttcgagaacaatgtcgttcacttgatgtggcaggagcccaaagaacccaacggtctg attgtgctgtacgaagtgagttatcgacgatacggcgatgaggagctgcatctctgtgtg tctcgcagacattttgccctggagcggggctgccggctgcgcgggctgccaccggggaac tacagtgtgcgagtgcgggccacctccctggcaggcaacggctcctggaccgaagccact tatttctacgtgacagactattacgtcccatcaaatattgcaaaaatcatcatcggcccc ctcatctttgtctttctcttcagtgtggtcattggaagcatttacctcttcttgagaaag aggcagccggatgggcccctgggaccgctgtacgcttcctcaaaccctgagtacctcagc gccagtgatgtgtttccctgctctgtgtacgtgccggacgagtgggaggtgcctcgggag aagatcaccctcctgcgggagctggggcagggctccttcggcatggtgtatgaaggcaac gccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacggtcaacgag tctgccagtctgcgagagaggatcgagtttctcaacgaggcctcagtcatgaagggcttc acctgccatcatgtggtccgcctcctgggggtggtatcgaaaggccagccaacgctggtg gtgatggagttgatggctcacggagacctgaagagctacctccgttccctgcggccggag gctgagaataaccctggtcgccctccccctaccctgcaagagatggttcagatggcggcg gagatcgccgacgggatggcgtacctgaacgctaagaagtttgtgcaccgggacctggca gctcgaaactgcatggtcgcccacgattttaccgtcaaaatcggagactttggaatgacc agagacatctacgaaacggattactaccggaaaggaggcaaggggctgctccctgtgagg tggatggctcctgaatccctgaaggacggggtctttactacttcttctgacatgtggtcc tttggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctgtct aatgagcaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaattgt cccgagagagtcaccgacctgatgcgtatgtgctggcagttcaaccccaagatgcggccg accttcctggagatcgtcgacctgctcaaggatgacctgcaccccagctttccagaagtt tccttcttccacagcgaggagaacaaggcccccgagagcgaggagctggagatggagttt gaggacatggagaatgtccccctggatcggtcctcacattcccagagggaggaggccggg ggccgggatgcagggtcctctctgggtctaaagcggaactatgaggaacacatcccgtac actcacatgaacgggggcaagaaaaacgggcggattctgactctgccgaggtcaaatcct tcctaa

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