Equus caballus (horse): 100051597
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Entry
100051597 CDS
T01058
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00010
Glycolysis / Gluconeogenesis
ecb00020
Citrate cycle (TCA cycle)
ecb00620
Pyruvate metabolism
ecb00785
Lipoic acid metabolism
ecb01100
Metabolic pathways
ecb01200
Carbon metabolism
ecb01210
2-Oxocarboxylic acid metabolism
ecb04066
HIF-1 signaling pathway
ecb04922
Glucagon signaling pathway
ecb05230
Central carbon metabolism in cancer
ecb05415
Diabetic cardiomyopathy
Module
ecb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100051597 (PDHA1)
00020 Citrate cycle (TCA cycle)
100051597 (PDHA1)
00620 Pyruvate metabolism
100051597 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100051597 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100051597 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100051597 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100051597 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100051597 (PDHA1)
Enzymes [BR:
ecb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100051597 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100051597
NCBI-ProteinID:
XP_001492207
Ensembl:
ENSECAG00000001964
LinkDB
All DBs
Position
X:15126210..15142810
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRSFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYFGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGHHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtttcccgtgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcctcccgtagttttgcaaacgatgctacgtttgaaattaagaaa
tgtgatctacaccggctggaagagggccctcctgtcacgacagtgctcaccagggaggac
gggctcagatactacaggatgatgcagactgtccgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcatcaaccccacagaccatcttatcacagcctatcgggct
cacggctttacctttactcgtgggctgtctgtccgagaaattctcgccgagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtatgccaagaacttc
tacgggggcaatggcattgtcggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtattttggaaaagatgaggtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatattcgaagcttacaatatggcggctttgtggaaattgccttgtattttc
atctgtgaaaataaccgctatggaatgggaacttctgttgagagagcagcagccagcact
gattattacaagagaggtgacttcatccctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggcgacaaggtttgcagctgcctattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
tatcgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatcatgcttctc
aaggatagaatggtgaacagcaaccttgccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgccgcccagtttgccacagctgatcctgaaccacct
ttggaagaactaggccatcacatctacagcagtgatccgccttttgaagttcgcggtgca
aatcagtggatcaagtttaagtccatcagttaa
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