Equus caballus (horse): 100051990
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Entry
100051990 CDS
T01058
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X4
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01524
Platinum drug resistance
ecb03440
Homologous recombination
ecb03460
Fanconi anemia pathway
ecb04120
Ubiquitin mediated proteolysis
ecb04151
PI3K-Akt signaling pathway
ecb05206
MicroRNAs in cancer
ecb05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100051990 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
100051990 (BRCA1)
03460 Fanconi anemia pathway
100051990 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
100051990 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100051990 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
100051990 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100051990 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ecb01009
]
100051990 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
ecb04121
]
100051990 (BRCA1)
03036 Chromosome and associated proteins [BR:
ecb03036
]
100051990 (BRCA1)
03400 DNA repair and recombination proteins [BR:
ecb03400
]
100051990 (BRCA1)
Enzymes [BR:
ecb01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100051990 (BRCA1)
Protein phosphatases and associated proteins [BR:
ecb01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100051990 (BRCA1)
Ubiquitin system [BR:
ecb04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
100051990 (BRCA1)
Multi subunit Ring-finger type E3
BRCC complex
100051990 (BRCA1)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
100051990 (BRCA1)
DNA repair and recombination proteins [BR:
ecb03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
100051990 (BRCA1)
BRCA1-A complex
100051990 (BRCA1)
BRCA1-B complex
100051990 (BRCA1)
BRCA1-C complex
100051990 (BRCA1)
BRCA complex
100051990 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
100051990 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_3
zf-C3HC4_4
zf-RING_5
zf-RING_2
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
Baculo_IE-1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
100051990
NCBI-ProteinID:
XP_014595447
Ensembl:
ENSECAG00000016974
VGNC:
15878
LinkDB
All DBs
Position
11:20121001..20182370
Genome browser
AA seq
1856 aa
AA seq
DB search
MDVSADRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLRIIHAFELDTGLQFAHSYSFSKKENDSPERVKE
EVSIIQSMGYRNRAKRHRQSEPENPTLQETSLSVHLSNLGIVRSLRTKQQIQPQNKSIYI
ELGSDSSEDTVNKASYCSLGDHELLQITPQGARAEASLNPTKKAACEFSEKAITNIEHHQ
SSNKDLTTTEKHAAEKHPEKYQGISVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
KAEFCNKSKQPGLAKSQQSRRAESKETCNDRQAPNSEEKLVLNADPLYGREELNKQKPPR
SDSPRDSQDVPWITLNSSIQKVNEWFSRSEEMLTSDDSCDGGPESNTEVAGAVEVPNEVR
GYSGSSEKIDLMAGDPSSALICESERVRSKPVENNIEDRIFGKTYRRKASFPNLSHITED
LIIGASAIEPQITQERSLTNRVKHKRRTSSGLHPEDFIKKVDLAVVQKTPEKIIEGTDQI
EQNSHVMNIIPNGHGNETKGDYVQNEKNANLTESLETESAFRTKAEPISSSIGNLELELN
IHSSKAPKKNRLRRKSCTKQIHALELVVSKNPSPPNHTELQIDSCSSSEEMKKKNSDQMP
VRHSKKLQLMEDKEPATGAKKSNKPNEQINKRLASDAFPELKLTNIPGFFTNCSSSNKLH
EFVNPSLQREEIEQNLGANRLSNSAKDPKDLILSGGKCLQAERSVESSGISLVPDTDYGT
QDSISLLEADTLGKAKTAPNQCANLCAAIENPKELTHDCSKDTRNDTQGVKDPLRREVNH
TQETSIEMEESEFDTQYLQNMFKVSKRQSFALFSNPGSPEKKCATVSAHSRSLRKRSPKV
TLKCGQKEGKEGKKESKIKNVQSVHTTVGFPVICQKDKKPGDYVKCSTKEASRLCQSSQF
RGNETELITANKHGISQNPYYIPSLSPIRSSVKTVCQKNLPEGKLEEQSLSPERAMGNES
IVQSTVSTISQNNIRESTLKEVSSSSINEVGSSINEVGSSGEHIQAELGRNRGPKLNAIL
RLGLMQPEVYKQSLPISNCKHLEIKRQGEKEVVQAVNADFSPCLISDNLEQPMGSSCASQ
VCSETPDDLLNDDEIKENISFAESGVKERSAVFSKSVQKGKFRRSPSPIGRTCLAQGHQR
RARKLESSEENTSSEDEELPCFQHLLFGKVTNLPSQSTSHAAATEGLSKKTEESLVSLQN
SLDDCSHQVALAEACQEHHLSEEARCSGSLFSSQCSALEDLPANTNTQEPVLMFDPPSKQ
VREQSENHEVVSDKELVSDDDEREPGLEEDSHHEEQSVDSILDEVASGYVSETNLSEDCS
GLSSQSDILTTQQRDTMQDNLIKLQQKMAELEAVLEQHGSQPSNRSPSLIADCCASEDLL
NPEQNTSERAVLTSEKSSEYPISQNPENLSADKFQISLDSSTSKNREPEMERSSPSKSQL
LDNRWCVHSHSRSLQNRNCPSQKEFIKAVDAEEQQLTKSEAQDLMEQSYLPRQDLEATPY
LESGISLFSHEPESDPSEERALEAAHVCSMPASTSAMKSLQFRVEESAKSPAGAHTTNIV
GSNVKEDSVSREKPEMISSTERVIRRISMVASGLTPKEFMLVHKFARKHHITLTNLVTEE
TTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKVLDEHDFEVRGDVVNG
RNHQGPKRARESQDRKIFRGLEICCCGPFTNMPTDQLEWMVRLCGASVVKEPSSFTFSEG
THPVVVVQPDAWTEDSGFHMIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQVP
NT seq
5571 nt
NT seq
+upstream
nt +downstream
nt
atggatgtatctgcggatcgcgttgaagaagtacaaaatgttctcaatgctatgcagaaa
atcttagagtgtccgatctgtctggagttgatcaaagagcccgtttccacaaaatgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatataaccaaaagaagcctccaagaaagtacaagatttagt
caacttgttgaagagctgttgagaatcattcatgcttttgaacttgacacaggactgcag
tttgcacatagttatagcttttcaaaaaaggaaaatgactctcctgagcgtgtaaaggag
gaagtttctatcatccaaagtatgggctaccgaaaccgtgccaaaagacatcgacagagt
gaacctgaaaatcctaccttgcaggaaaccagtcttagtgtccacctctctaaccttgga
attgtgagatctctgaggacaaagcaacagatacaacctcagaataagtctatctacatt
gaattgggatctgattcttctgaagatacagttaataaggcaagttattgcagtttggga
gaccacgaattgttacaaatcactcctcaaggagccagggctgaagccagtttgaatcct
acaaaaaaggctgcttgtgagttttctgagaaggccataacaaatattgaacatcatcaa
tccagtaataaagatttgaccaccactgagaagcatgcagctgagaagcatccagaaaag
tatcagggtatttctgtttcaaacttgcatgtggagccatgtggcacaaatactcatgcc
agctcattgcagcatgagaacagcagtttattactcactaaagacagaatgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcctggcttagcaaagagccaacagagcaga
cgggctgaaagtaaggaaacatgtaatgataggcaggcccccaactcagaggaaaagcta
gttctgaatgctgatccgctgtatgggagagaagaactgaataagcagaaacctccacgc
tctgacagtcctagagactcccaagatgttccttggataacactgaatagtagcatacag
aaagttaatgagtggttttccagaagtgaggaaatgttaacttctgatgactcatgtgac
ggagggcctgaatcaaatacagaagtagctggtgcagtagaagttccaaatgaagtacgt
ggatattctggttcttcagagaaaatagacttaatggccggtgatccttctagtgcttta
atatgtgaaagtgaaagagtccgctccaaaccagtagagaataatattgaagatagaata
tttgggaaaacctatcggaggaaggcaagcttccctaacttgagccacataactgaagat
ctaattataggggcatctgctatagaacctcagattacacaagagcgttcactcacaaat
agagtgaagcataaaaggagaacgtcatcaggccttcatcctgaggattttatcaagaaa
gtagatttggcagttgtccaaaagactcctgaaaagataattgagggaactgaccaaata
gagcagaacagtcatgtgatgaatattattcctaatggtcatgggaatgaaacaaaaggc
gattatgttcagaatgagaaaaacgctaacctaacagaatcattggagacagaatctgct
ttcagaactaaagctgaacctataagcagcagcataggcaatctggaactggaattaaat
atccacagttcaaaagcacctaagaagaataggctgaggaggaagtcttgtaccaagcag
attcatgcacttgaactagtagtcagtaaaaatccaagcccacctaatcatactgaacta
caaatcgatagttgttctagtagtgaagagatgaagaaaaaaaattctgaccaaatgccg
gtcagacacagcaaaaagcttcaactcatggaagataaagaacctgccactggagccaaa
aagagtaacaagccaaatgaacaaataaataaaagacttgccagtgatgcttttccagag
ctaaaattaacaaacatacctggtttttttactaactgttcaagttctaataaacttcat
gagtttgtcaatcctagccttcaaagagaagaaatagaacagaacctaggagcaaatcga
ctgtctaatagtgccaaagaccccaaagatctgatattaagtggaggaaaatgtttgcaa
gctgaaagatctgtagagagttccggtatttcattggtacctgatactgattatgggact
caggatagtatctcactgctggaagctgacaccctagggaaggcaaaaacagcaccaaat
caatgtgcaaatctatgcgcagcaattgaaaaccccaaggaacttacccatgattgttct
aaggatactagaaatgatacacagggcgttaaggatccattgagacgtgaagttaaccac
actcaggagacaagcatagaaatggaagagagtgaatttgatacgcagtatctacagaat
atgttcaaggtttcaaagcgtcagtcatttgctctgttttcaaatccaggaagtccagaa
aagaagtgtgcaacagtcagtgcccactccaggtccttaaggaaacgaagtccaaaagtc
actcttaaatgtggacaaaaagaaggaaaggagggaaagaaagagtctaaaatcaagaat
gtgcagtcagttcacacaactgtgggctttcctgtgatttgtcagaaagataagaagcca
ggtgactatgtcaaatgtagcacaaaagaagcctctaggctttgtcagtcatctcagttc
agaggcaacgaaactgaacttattactgcaaataaacatggaatttcacaaaacccatat
tatataccatcactttctcccatcaggtcatctgttaaaactgtatgtcagaaaaacctg
ccagagggaaagcttgaggaacagtcactgtcacctgaaagagcaatgggaaatgagagc
attgttcaaagtacagtgagcacaattagccaaaataacattagagaaagcacattgaaa
gaagtcagctcaagcagtattaatgaagtaggctctagtattaatgaagtaggttccagt
ggtgaacacattcaagcagaactaggcagaaacagaggacctaaattaaatgctattctc
agattaggtcttatgcaacctgaagtctataagcaaagtcttcctataagtaattgtaaa
catctggaaataaaaaggcaaggagaaaaggaagtagttcaggctgttaacgcagacttt
tctccgtgtctaatttcagataacctagaacaacctatgggaagtagttgtgcttctcag
gtttgttctgagacacctgatgacctgttaaatgatgacgaaataaaggaaaatatcagc
tttgctgaaagtggcgttaaggaaagatctgccgtttttagcaaaagcgtccagaaagga
aagttcagaaggagtcctagccctataggccgtacgtgtttggctcagggtcaccaaaga
cgggccaggaaattagagtcctcagaagagaacacgtctagtgaggatgaagagcttccc
tgcttccaacacttactatttggtaaagtaaccaatctaccttctcaatctaccagccat
gctgctgccacggaaggtctgtctaagaaaacagaggagagcctagtatcattgcagaat
agcttagatgactgcagtcaccaggtggcgttggcagaggcatgccaggaacatcacctg
agtgaggaagcgagatgttccggtagcttattttcttcccagtgcagtgcgttggaagac
ttgcctgctaatacgaacacccaggagcctgtcttgatgtttgatcctccttccaaacaa
gtgagggaacaatctgaaaaccacgaagttgtgagtgacaaggaattggtttcagatgat
gacgaacgggaacctggcctggaagaggatagtcaccacgaagagcagagtgtggattca
atcttagatgaagtagcgtccgggtatgtgagtgaaacaaatctctcggaagactgttca
gggctctcctctcagagtgatattttaaccactcagcagagggataccatgcaagataac
ctgataaagcttcagcagaagatggccgagctggaagctgtgttagagcagcacgggagc
cagccttctaaccgctccccttccctcatagctgattgttgtgcctctgaggacctgcta
aatccagaacaaaacacatcagaaagagcagtattaacttcagagaaaagtagtgaatat
cctataagccagaatccagaaaacctttctgctgacaagtttcaaatatctctggatagt
tccaccagtaaaaatagagaaccagaaatggaaaggtcttccccttctaaatcccagttg
ttagataataggtggtgtgtgcacagtcactcaaggagtcttcagaacagaaactgccca
tctcaaaaggagttcattaaggctgttgatgcggaggagcagcaactgacaaaatctgag
gcccaagatttaatggagcagtcttatttgccaagacaagatctagaggcaaccccttac
ctggaatctggaattagcctgttctctcatgagcctgagtctgatccctctgaagagaga
gctctagaggcagctcatgtttgcagcatgccagcttcaacctctgcgatgaaatcactc
caatttcgagttgaagaatctgccaagagtccagctggtgctcatactactaatattgtt
gggtctaatgtgaaggaagacagtgtgagcagggagaagccagaaatgatatcttcgacc
gaaagagtcatcagaagaatatccatggtggcctcaggcttgaccccaaaagaatttatg
cttgtgcacaagtttgccagaaaacaccacatcactttaactaatctagttactgaagag
actactcatgtcattatgaaaacagatgctgaatttgtgtgtgaacggacactgaaatat
tttctgggaattgcaggaggaaaatgggtagttagctatttctgggtgacccagtctatt
aaagaaagaaaggtgctggatgagcatgattttgaagtcagaggagatgttgtgaatgga
agaaaccaccaagggccaaagcgagcaagagaatcccaggacagaaagatcttcaggggc
ctagaaatctgttgctgtgggccatttaccaacatgcccacagatcaactagagtggatg
gtgcgcctctgtggggcttctgtggtgaaggagccttcatcgttcaccttcagtgagggt
actcacccagttgtggtcgtgcaaccggacgcctggacagaggacagcggcttccatatg
attgggcagatgtgtgaggcacctgtggtgacccgagagtgggtgttggacagcgtagcc
ctctaccagtgccaggagctggacacctacctcataccccaggttccctag
DBGET
integrated database retrieval system
