KEGG   Equus caballus (horse): 100053056
Entry
100053056         CDS       T01058                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04010  MAPK signaling pathway
ecb04015  Rap1 signaling pathway
ecb04218  Cellular senescence
ecb04380  Osteoclast differentiation
ecb04620  Toll-like receptor signaling pathway
ecb04664  Fc epsilon RI signaling pathway
ecb04668  TNF signaling pathway
ecb04750  Inflammatory mediator regulation of TRP channels
ecb04912  GnRH signaling pathway
ecb04935  Growth hormone synthesis, secretion and action
ecb04936  Alcoholic liver disease
ecb05014  Amyotrophic lateral sclerosis
ecb05022  Pathways of neurodegeneration - multiple diseases
ecb05132  Salmonella infection
ecb05135  Yersinia infection
ecb05145  Toxoplasmosis
ecb05161  Hepatitis B
ecb05163  Human cytomegalovirus infection
ecb05167  Kaposi sarcoma-associated herpesvirus infection
ecb05169  Epstein-Barr virus infection
ecb05170  Human immunodeficiency virus 1 infection
ecb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05417  Lipid and atherosclerosis
ecb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100053056 (MAP2K6)
   04015 Rap1 signaling pathway
    100053056 (MAP2K6)
   04668 TNF signaling pathway
    100053056 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100053056 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100053056 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    100053056 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100053056 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    100053056 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100053056 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100053056 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100053056 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100053056 (MAP2K6)
   05161 Hepatitis B
    100053056 (MAP2K6)
   05163 Human cytomegalovirus infection
    100053056 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100053056 (MAP2K6)
   05169 Epstein-Barr virus infection
    100053056 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100053056 (MAP2K6)
   05135 Yersinia infection
    100053056 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100053056 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100053056 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    100053056 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100053056 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    100053056 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100053056 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100053056 (MAP2K6)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100053056 (MAP2K6)
Protein kinases [BR:ecb01001]
 Serine/threonine kinases: STE group
  STE7 family
   100053056 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 100053056
NCBI-ProteinID: XP_001498802
Ensembl: ENSECAG00000010077
VGNC: 19929
UniProt: A0A9L0SV87
LinkDB
Position
11:complement(11354389..11471257)
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGSQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccccggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaagcttgcatttct
attggaagtcagaactttgaggtgaaggcggatgacctggagcctatagtggaactggga
cgaggtgcgtacggggtagtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctattgatggatttg
gatatttccatgaggacagtggactgtccttttacagtcaccttttatggcgcactcttc
cgggagggtgatgtctggatctgcatggagctcatggatacgtcgctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaagacatcttagggaaaatagccgtt
tcgattgtaaaagcattagaacatttacacagtaaactctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaatactctgggccaagtgaagatgtgtgattttggaatc
agtggctaccttgtagactctgttgctaaaaccattgatgcaggatgcaaaccatacatg
gctcctgaaagaataaaccccgagctcaaccagaagggatacagtgtgaagtctgacatc
tggagtctcggcatcacaatgattgagttggccatccttcggtttccttatgattcgtgg
ggaacgccttttcagcagctcaaacaggtggtagaggagccatcaccgcaactcccggca
gacaagttctccgaagagtttgttgactttacctcgcagtgcttgaagaagaattccaaa
gaacggccaacatatccagagcttatgcaacatccatttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattcttggagactaa

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