Equus caballus (horse): 100055384
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Entry
100055384 CDS
T01058
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X4
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04620
Toll-like receptor signaling pathway
ecb04621
NOD-like receptor signaling pathway
ecb04622
RIG-I-like receptor signaling pathway
ecb04623
Cytosolic DNA-sensing pathway
ecb04625
C-type lectin receptor signaling pathway
ecb04657
IL-17 signaling pathway
ecb04936
Alcoholic liver disease
ecb05160
Hepatitis C
ecb05161
Hepatitis B
ecb05162
Measles
ecb05164
Influenza A
ecb05165
Human papillomavirus infection
ecb05167
Kaposi sarcoma-associated herpesvirus infection
ecb05168
Herpes simplex virus 1 infection
ecb05169
Epstein-Barr virus infection
ecb05171
Coronavirus disease - COVID-19
ecb05207
Chemical carcinogenesis - receptor activation
ecb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100055384 (IKBKE)
04621 NOD-like receptor signaling pathway
100055384 (IKBKE)
04622 RIG-I-like receptor signaling pathway
100055384 (IKBKE)
04623 Cytosolic DNA-sensing pathway
100055384 (IKBKE)
04625 C-type lectin receptor signaling pathway
100055384 (IKBKE)
04657 IL-17 signaling pathway
100055384 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100055384 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
100055384 (IKBKE)
05160 Hepatitis C
100055384 (IKBKE)
05171 Coronavirus disease - COVID-19
100055384 (IKBKE)
05164 Influenza A
100055384 (IKBKE)
05162 Measles
100055384 (IKBKE)
05168 Herpes simplex virus 1 infection
100055384 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
100055384 (IKBKE)
05169 Epstein-Barr virus infection
100055384 (IKBKE)
05165 Human papillomavirus infection
100055384 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100055384 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100055384 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100055384 (IKBKE)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100055384 (IKBKE)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: Other
IKK family [OT]
100055384 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
RH_dom
Motif
Other DBs
NCBI-GeneID:
100055384
NCBI-ProteinID:
XP_005609661
Ensembl:
ENSECAG00000000352
VGNC:
18985
LinkDB
All DBs
Position
5:2744983..2769591
Genome browser
AA seq
740 aa
AA seq
DB search
MQSTVNYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTASYMRPREVQVREFEVLR
KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNIMRLLGEEGQSIYKLTDFGAARELDDDEKFISVYGTEEYL
HPDMYERAVLRKPQQKAFGVAVDLWSIGVTLYHAATGSLPFVPFGGPRRNKEIMYRITTE
KPAGAIAGTQRRENGPLEWSYSLPITCRLSSGLQSQLVPILANILEVEQAKCWGFDQFFA
ETSDILQRVIVHVFSLSEAVLHHVYIHGHNTIAIFLEAVYEQTNVAPQHQEYLFEGHLCV
LEPNLSAQHIAHTTASSPLTLFSMASETPKGLAFRDPALDIPKFVPKVDLQADYNTAKGV
LGAGYQALRLAQALLAGQELMLRGLHWFVEILQATCRRTLEVTRMALLFLSSSLGTDRFS
NGAGTPEIQELKRATELRSQLRTLAGVLSRCSHNITETQMSLSSLSSELVKNRDQVHEDR
STQKIQCCLDKMYLIYKQFKKSRVRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQ
KYQTSLVTHGKHMRVVHETRNHLRLVGCSVAACNTEAQGAQESLSKLLDRLSQQLLQDRA
KGAQASPPPTAPYPSPALKDLVLHMQELYEEMKLLAFDLQDNNRIIEGNCWVYKKRICLT
LMLTPLSVQSEAEAQRHVDL
NT seq
2223 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcaccgtcaattacctgtggcacaccgacgacctgctggggcagggggccacc
gccagtgtgtacaaggcccgaaacaagaaatccggggagctggttgctgtgaaggtcttc
aacactgccagctacatgcgaccccgcgaggtgcaggtgagggagttcgaggtcctgcgg
aagctgaaccaccagaacatcgtcaagctcttcgcggtggaggagacggggggcagccgg
cagaaggtgctggtgatggagtactgctccagtgggagcctgctgagcgtgcttgagagc
cccgagaacgccttcgggctgccggaggacgagttcctggtggtgctgcgctgtgtggtg
gctggcatgaaccacctgcgggagaacggcatcgtccaccgtgacatcaagcccgggaac
atcatgcgcctcctgggggaggaggggcagagcatctacaagctgacggacttcggggcc
gcccgcgagctggacgacgatgagaagttcatctcggtctatgggactgaggagtacctg
caccctgacatgtatgagcgggcagtgcttcgcaagccccagcagaaggcgttcggggtg
gctgtggatctctggagcattggggtgaccctgtaccacgcagccaccggcagcctgccc
tttgtccccttcggtgggccacggcgaaacaaagagatcatgtaccggataaccacagag
aagccagccggggccattgcaggcacccagaggcgggaaaacgggcctttggagtggagc
tacagcctccccatcacctgccggctgtcatcggggctgcagagccagctggtgcccatc
ctggccaacatcctggaggtggagcaggccaagtgctggggcttcgaccagttctttgcg
gagaccagcgacatcctgcagcgagtcattgtgcacgtcttctccctgtccgaggcggtc
ctgcaccacgtctacatccatggccacaacacgatagccatctttctggaggctgtgtat
gagcagaccaatgtggccccccagcaccaggagtacctctttgagggtcacctctgtgtc
ctcgagcccaacctgtcagcacagcacattgcccacacgacggcaagcagccccctgacc
ctgttcagcatggccagcgagacccccaagggactggccttcagggacccggctctggac
atccccaagtttgttcccaaagtggacctgcaggcagattacaacacggccaagggcgtg
ttgggcgcaggctaccaggccctgcggctggcgcaggccctgctggctgggcaggagctc
atgcttcgggggctgcactggtttgtggagatcctccaggccacgtgcaggcggacactg
gaggtcacgaggatggccctcctcttcctcagcagcagcctgggcaccgacaggttcagc
aatggggctgggacgcctgaaatccaggaattgaagagggccacagaactgaggtcccag
ctgcggactctggctggggtcctctccaggtgttcccacaatatcacagagacccagatg
agcctgagcagcctgagctctgagctggtgaagaatcgggatcaggtacatgaagacaga
agcacccagaagattcagtgctgtctggacaagatgtaccttatctacaaacagttcaag
aaatcccgggtgaggccagggctcggctacaatgaggagcagattcacaagctggataag
gtgaattttagccatttagctaaaaggctcctgcaagtgttccaggaggagtgtgtacag
aagtatcagacatctctggtcacacacggcaagcacatgagggtggtgcacgagaccagg
aaccacctgcgcctggtcggctgctccgtggccgcctgtaacaccgaagcccagggagcc
caggagagcctcagcaagctccttgaccggctgtctcagcagctcctccaggacagagca
aagggggctcaggcctccccaccccccacagctccttatcccagccctgcgctgaaggac
ctcgttctccacatgcaggagctctacgaggagatgaagctgctggcatttgacctccag
gacaacaaccgcatcatcgaaggcaattgctgggtgtacaaaaagagaatctgtttgacc
ctgatgctcacaccactctcagtgcagtcagaggcagaggctcagaggcacgtggatttg
tga
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