Equus caballus (horse): 100056239
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Entry
100056239 CDS
T01058
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01522
Endocrine resistance
ecb04010
MAPK signaling pathway
ecb04015
Rap1 signaling pathway
ecb04068
FoxO signaling pathway
ecb04071
Sphingolipid signaling pathway
ecb04114
Oocyte meiosis
ecb04148
Efferocytosis
ecb04218
Cellular senescence
ecb04261
Adrenergic signaling in cardiomyocytes
ecb04370
VEGF signaling pathway
ecb04380
Osteoclast differentiation
ecb04550
Signaling pathways regulating pluripotency of stem cells
ecb04611
Platelet activation
ecb04613
Neutrophil extracellular trap formation
ecb04620
Toll-like receptor signaling pathway
ecb04621
NOD-like receptor signaling pathway
ecb04622
RIG-I-like receptor signaling pathway
ecb04625
C-type lectin receptor signaling pathway
ecb04657
IL-17 signaling pathway
ecb04658
Th1 and Th2 cell differentiation
ecb04659
Th17 cell differentiation
ecb04660
T cell receptor signaling pathway
ecb04664
Fc epsilon RI signaling pathway
ecb04668
TNF signaling pathway
ecb04670
Leukocyte transendothelial migration
ecb04714
Thermogenesis
ecb04722
Neurotrophin signaling pathway
ecb04723
Retrograde endocannabinoid signaling
ecb04728
Dopaminergic synapse
ecb04750
Inflammatory mediator regulation of TRP channels
ecb04912
GnRH signaling pathway
ecb04914
Progesterone-mediated oocyte maturation
ecb04917
Prolactin signaling pathway
ecb04926
Relaxin signaling pathway
ecb04932
Non-alcoholic fatty liver disease
ecb04933
AGE-RAGE signaling pathway in diabetic complications
ecb04935
Growth hormone synthesis, secretion and action
ecb04936
Alcoholic liver disease
ecb05014
Amyotrophic lateral sclerosis
ecb05020
Prion disease
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05132
Salmonella infection
ecb05133
Pertussis
ecb05135
Yersinia infection
ecb05140
Leishmaniasis
ecb05142
Chagas disease
ecb05145
Toxoplasmosis
ecb05152
Tuberculosis
ecb05161
Hepatitis B
ecb05163
Human cytomegalovirus infection
ecb05167
Kaposi sarcoma-associated herpesvirus infection
ecb05169
Epstein-Barr virus infection
ecb05170
Human immunodeficiency virus 1 infection
ecb05171
Coronavirus disease - COVID-19
ecb05205
Proteoglycans in cancer
ecb05208
Chemical carcinogenesis - reactive oxygen species
ecb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05415
Diabetic cardiomyopathy
ecb05417
Lipid and atherosclerosis
ecb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100056239 (MAPK12)
04015 Rap1 signaling pathway
100056239 (MAPK12)
04370 VEGF signaling pathway
100056239 (MAPK12)
04668 TNF signaling pathway
100056239 (MAPK12)
04068 FoxO signaling pathway
100056239 (MAPK12)
04071 Sphingolipid signaling pathway
100056239 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100056239 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
100056239 (MAPK12)
04218 Cellular senescence
100056239 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100056239 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100056239 (MAPK12)
04613 Neutrophil extracellular trap formation
100056239 (MAPK12)
04620 Toll-like receptor signaling pathway
100056239 (MAPK12)
04621 NOD-like receptor signaling pathway
100056239 (MAPK12)
04622 RIG-I-like receptor signaling pathway
100056239 (MAPK12)
04625 C-type lectin receptor signaling pathway
100056239 (MAPK12)
04660 T cell receptor signaling pathway
100056239 (MAPK12)
04658 Th1 and Th2 cell differentiation
100056239 (MAPK12)
04659 Th17 cell differentiation
100056239 (MAPK12)
04657 IL-17 signaling pathway
100056239 (MAPK12)
04664 Fc epsilon RI signaling pathway
100056239 (MAPK12)
04670 Leukocyte transendothelial migration
100056239 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
100056239 (MAPK12)
04914 Progesterone-mediated oocyte maturation
100056239 (MAPK12)
04917 Prolactin signaling pathway
100056239 (MAPK12)
04926 Relaxin signaling pathway
100056239 (MAPK12)
04935 Growth hormone synthesis, secretion and action
100056239 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100056239 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
100056239 (MAPK12)
04723 Retrograde endocannabinoid signaling
100056239 (MAPK12)
04722 Neurotrophin signaling pathway
100056239 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100056239 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
100056239 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
100056239 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100056239 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
100056239 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100056239 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100056239 (MAPK12)
05161 Hepatitis B
100056239 (MAPK12)
05171 Coronavirus disease - COVID-19
100056239 (MAPK12)
05163 Human cytomegalovirus infection
100056239 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
100056239 (MAPK12)
05169 Epstein-Barr virus infection
100056239 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
100056239 (MAPK12)
05135 Yersinia infection
100056239 (MAPK12)
05133 Pertussis
100056239 (MAPK12)
05152 Tuberculosis
100056239 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100056239 (MAPK12)
05140 Leishmaniasis
100056239 (MAPK12)
05142 Chagas disease
100056239 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100056239 (MAPK12)
05020 Prion disease
100056239 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
100056239 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100056239 (MAPK12)
05418 Fluid shear stress and atherosclerosis
100056239 (MAPK12)
05415 Diabetic cardiomyopathy
100056239 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100056239 (MAPK12)
04932 Non-alcoholic fatty liver disease
100056239 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
100056239 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100056239 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100056239 (MAPK12)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
100056239 (MAPK12)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
100056239 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Kdo
Haspin_kinase
UvrD_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100056239
NCBI-ProteinID:
XP_023487088
Ensembl:
ENSECAG00000017373
VGNC:
19957
LinkDB
All DBs
Position
28:complement(46883056..46892148)
Genome browser
AA seq
367 aa
AA seq
DB search
MSSPPPARRGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEIMK
VTGTPPADFVQRLQSVEAKNYMKGLPELEKKDFASILTNASPLAVSLLERMLVLDAERRV
TAAEALAHPYFESLQDAEDEPRAQKYDESFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAK
VSKETAL
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgccgcccgcccgcaggggcttttaccgccaagaagtaaccaagacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctcgggcgcctacggcgcc
gtgtgctcggccgtggacagccgcacaggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtccgagttgttcgccaagcgcgcctaccgcgagctgcgcctccttaagcac
atgcgccacgagaacgtgattgggctgctggatgtgttcactcctgacgagaccctggat
gacttcacagatttctatctggtgatgccgttcatgggcactgacctgggcaagctcatg
aagcatgagaagctgagtgaggaccggatccagtttcttgtctaccagatgttgaaggga
ctgaagtatatccatgctgctggtgtcatccacagggacctgaagcctggcaacctggcg
gtgaacgaggactgtgagctgaagatcctggacttcggcctggccaggcaggcagatagt
gagatgaccggatacgtggtgacccggtggtaccgggcgcctgaggtcatattgaattgg
atgcactacacacagacggtggacatctggtcagtgggctgcatcatggcagagatgatc
acggggaagacgttattcaagggcaacgaccacctggaccagctgaaggagatcatgaag
gtgacagggacgcctcccgcagactttgtgcagaggctgcagagcgtagaagcgaagaac
tacatgaagggcctccccgagctggagaagaaggattttgcctcaatcttgaccaatgca
agccctctggccgtgagcctgctggagagaatgctggtgctcgatgcagagcggcgggtg
acagcggccgaggcactggcccacccctacttcgagtcactgcaggacgcggaggatgaa
cccagggcccagaagtacgacgagtcctttgatgacgtggaccgcacgctggatgagtgg
aagcgtgtcacgtataaagaggtgctcagcttcaagcctccccggcagctgggagccaag
gtctccaaggagacagccctgtga
DBGET
integrated database retrieval system