KEGG   Equus caballus (horse): 100057357
Entry
100057357         CDS       T01058                                 
Symbol
PPP3CC
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04010  MAPK signaling pathway
ecb04020  Calcium signaling pathway
ecb04022  cGMP-PKG signaling pathway
ecb04114  Oocyte meiosis
ecb04218  Cellular senescence
ecb04310  Wnt signaling pathway
ecb04360  Axon guidance
ecb04370  VEGF signaling pathway
ecb04380  Osteoclast differentiation
ecb04625  C-type lectin receptor signaling pathway
ecb04650  Natural killer cell mediated cytotoxicity
ecb04658  Th1 and Th2 cell differentiation
ecb04659  Th17 cell differentiation
ecb04660  T cell receptor signaling pathway
ecb04662  B cell receptor signaling pathway
ecb04720  Long-term potentiation
ecb04724  Glutamatergic synapse
ecb04728  Dopaminergic synapse
ecb04921  Oxytocin signaling pathway
ecb04922  Glucagon signaling pathway
ecb04924  Renin secretion
ecb05010  Alzheimer disease
ecb05014  Amyotrophic lateral sclerosis
ecb05020  Prion disease
ecb05022  Pathways of neurodegeneration - multiple diseases
ecb05031  Amphetamine addiction
ecb05152  Tuberculosis
ecb05163  Human cytomegalovirus infection
ecb05166  Human T-cell leukemia virus 1 infection
ecb05167  Kaposi sarcoma-associated herpesvirus infection
ecb05170  Human immunodeficiency virus 1 infection
ecb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100057357 (PPP3CC)
   04310 Wnt signaling pathway
    100057357 (PPP3CC)
   04370 VEGF signaling pathway
    100057357 (PPP3CC)
   04020 Calcium signaling pathway
    100057357 (PPP3CC)
   04022 cGMP-PKG signaling pathway
    100057357 (PPP3CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100057357 (PPP3CC)
   04218 Cellular senescence
    100057357 (PPP3CC)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100057357 (PPP3CC)
   04650 Natural killer cell mediated cytotoxicity
    100057357 (PPP3CC)
   04660 T cell receptor signaling pathway
    100057357 (PPP3CC)
   04658 Th1 and Th2 cell differentiation
    100057357 (PPP3CC)
   04659 Th17 cell differentiation
    100057357 (PPP3CC)
   04662 B cell receptor signaling pathway
    100057357 (PPP3CC)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100057357 (PPP3CC)
   04921 Oxytocin signaling pathway
    100057357 (PPP3CC)
   04924 Renin secretion
    100057357 (PPP3CC)
  09156 Nervous system
   04724 Glutamatergic synapse
    100057357 (PPP3CC)
   04728 Dopaminergic synapse
    100057357 (PPP3CC)
   04720 Long-term potentiation
    100057357 (PPP3CC)
  09158 Development and regeneration
   04360 Axon guidance
    100057357 (PPP3CC)
   04380 Osteoclast differentiation
    100057357 (PPP3CC)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100057357 (PPP3CC)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100057357 (PPP3CC)
   05170 Human immunodeficiency virus 1 infection
    100057357 (PPP3CC)
   05163 Human cytomegalovirus infection
    100057357 (PPP3CC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100057357 (PPP3CC)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100057357 (PPP3CC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100057357 (PPP3CC)
   05014 Amyotrophic lateral sclerosis
    100057357 (PPP3CC)
   05020 Prion disease
    100057357 (PPP3CC)
   05022 Pathways of neurodegeneration - multiple diseases
    100057357 (PPP3CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    100057357 (PPP3CC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100057357 (PPP3CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ecb01009]
    100057357 (PPP3CC)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100057357 (PPP3CC)
Protein phosphatases and associated proteins [BR:ecb01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100057357 (PPP3CC)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 100057357
NCBI-ProteinID: XP_023491911
Ensembl: ENSECAG00000009540
VGNC: 21787
LinkDB
Position
2:51546824..51644536
AA seq 534 aa
MSGRNVHLSTTERVIKAVPFPPTQRLTLKEVFENGKPKIDVLKNHLVKEGRLEEEVALKI
INDGAAILRQEETMLEVDAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLFLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEQVYDACMDTFDC
LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFKEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNILNICSDDELISDDEIEDHYISSYQKGGTTVRKEIIKNKIRAIGKMARVFSVLREES
ESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHRIRSFEEARGLD
RINERMPPRKESQHSDGPVKLVTPAQPNATHRSDKGTKASDNSESCGGTGGSKT
NT seq 1605 nt   +upstreamnt  +downstreamnt
atgtccgggaggaacgtccacctctccaccaccgaacgcgtcattaaagctgtccccttt
cctccaacccagcggcttactttgaaggaagtatttgagaatgggaaacctaaaattgat
gttttgaaaaaccatttggtgaaggaagggcgactggaagaggaagtagccctaaagata
atcaacgatggggctgccattctgagacaagaggagactatgctcgaagtagatgctcca
atcacagtgtgtggcgatgttcatgggcaattctttgacttgatgaaattatttgaagtt
ggaggatcacctagtaatacacgctacctctttcttggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtttttatggagtttaaagatcaatcatcctaaaacattg
tttctgcttcgaggaaatcatgaatgcaggcatcttacagagtattttaccttcaaacag
gaatgtcgaatcaaatattctgaacaggtgtatgatgcgtgtatggatacatttgactgt
cttcctcttgctgccctcttaaaccagcagtttctgtgtgtccatggagggatgtcacct
gaaatcactagtttagatgacattaggaaattagacaggtttaaggagcctccagccttt
gggccagtgtgtgaccttctttggtctgatccctcagaggattacggcaatgagaagacc
ttggagcactatacccacaacactgtccgagggtgctcgtatttttacagttaccctgca
gtttgtgaatttttgcagaacaataatttgttatcaataatcagagcccatgaagcccaa
gatgccgggtatcgaatgtacaggaagagccaaacaacaggctttccatcactcattaca
attttctctgcccccaattacctagatgtctataacaataaagctgctgtgttaaaatat
gagaacaacgtcatgaacatccggcagttcaactgttctcctcacccctactggcttccg
aacttcatggatgttttcacgtggtctttgccttttgttggggagaaagtcacagagatg
ctggttaacattctcaacatatgctctgatgatgaattgatttccgatgatgaaattgaa
gatcactacatttcaagctatcagaaaggaggcactacagttcgaaaggagatcatcaag
aataaaatcagagccattgggaagatggcccgggtcttttcagttcttcgggaagagagt
gagagtgtgctgaccctcaagggcctgacccctacaggcacactccctctgggtgtcctc
tcgggaggaaagcagactattgagacagccacagtagaagcggtagaggcccgggaagcc
atcagagggttttcgcttcagcacaggatccggagttttgaagaagcccgaggtctggac
cgaattaatgagcggatgccaccccgaaaagaaagccaacactctgatgggccagtgaaa
ttagtaacccctgcacaaccaaatgccacgcacaggagcgacaagggaacaaaagccagt
gacaactcagagtcctgtggtggcactggtggatccaaaacttaa

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