Equus caballus (horse): 100057701
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Entry
100057701 CDS
T01058
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1 isoform X2
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01521
EGFR tyrosine kinase inhibitor resistance
ecb01522
Endocrine resistance
ecb01524
Platinum drug resistance
ecb04010
MAPK signaling pathway
ecb04012
ErbB signaling pathway
ecb04014
Ras signaling pathway
ecb04015
Rap1 signaling pathway
ecb04022
cGMP-PKG signaling pathway
ecb04024
cAMP signaling pathway
ecb04062
Chemokine signaling pathway
ecb04066
HIF-1 signaling pathway
ecb04068
FoxO signaling pathway
ecb04071
Sphingolipid signaling pathway
ecb04072
Phospholipase D signaling pathway
ecb04114
Oocyte meiosis
ecb04140
Autophagy - animal
ecb04148
Efferocytosis
ecb04150
mTOR signaling pathway
ecb04151
PI3K-Akt signaling pathway
ecb04210
Apoptosis
ecb04218
Cellular senescence
ecb04261
Adrenergic signaling in cardiomyocytes
ecb04270
Vascular smooth muscle contraction
ecb04350
TGF-beta signaling pathway
ecb04360
Axon guidance
ecb04370
VEGF signaling pathway
ecb04371
Apelin signaling pathway
ecb04380
Osteoclast differentiation
ecb04510
Focal adhesion
ecb04520
Adherens junction
ecb04540
Gap junction
ecb04550
Signaling pathways regulating pluripotency of stem cells
ecb04611
Platelet activation
ecb04613
Neutrophil extracellular trap formation
ecb04620
Toll-like receptor signaling pathway
ecb04621
NOD-like receptor signaling pathway
ecb04625
C-type lectin receptor signaling pathway
ecb04650
Natural killer cell mediated cytotoxicity
ecb04657
IL-17 signaling pathway
ecb04658
Th1 and Th2 cell differentiation
ecb04659
Th17 cell differentiation
ecb04660
T cell receptor signaling pathway
ecb04662
B cell receptor signaling pathway
ecb04664
Fc epsilon RI signaling pathway
ecb04666
Fc gamma R-mediated phagocytosis
ecb04668
TNF signaling pathway
ecb04713
Circadian entrainment
ecb04720
Long-term potentiation
ecb04722
Neurotrophin signaling pathway
ecb04723
Retrograde endocannabinoid signaling
ecb04724
Glutamatergic synapse
ecb04725
Cholinergic synapse
ecb04726
Serotonergic synapse
ecb04730
Long-term depression
ecb04810
Regulation of actin cytoskeleton
ecb04910
Insulin signaling pathway
ecb04912
GnRH signaling pathway
ecb04914
Progesterone-mediated oocyte maturation
ecb04915
Estrogen signaling pathway
ecb04916
Melanogenesis
ecb04917
Prolactin signaling pathway
ecb04919
Thyroid hormone signaling pathway
ecb04921
Oxytocin signaling pathway
ecb04926
Relaxin signaling pathway
ecb04928
Parathyroid hormone synthesis, secretion and action
ecb04929
GnRH secretion
ecb04930
Type II diabetes mellitus
ecb04933
AGE-RAGE signaling pathway in diabetic complications
ecb04934
Cushing syndrome
ecb04935
Growth hormone synthesis, secretion and action
ecb04960
Aldosterone-regulated sodium reabsorption
ecb05010
Alzheimer disease
ecb05020
Prion disease
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05034
Alcoholism
ecb05132
Salmonella infection
ecb05133
Pertussis
ecb05135
Yersinia infection
ecb05140
Leishmaniasis
ecb05142
Chagas disease
ecb05145
Toxoplasmosis
ecb05152
Tuberculosis
ecb05160
Hepatitis C
ecb05161
Hepatitis B
ecb05163
Human cytomegalovirus infection
ecb05164
Influenza A
ecb05165
Human papillomavirus infection
ecb05166
Human T-cell leukemia virus 1 infection
ecb05167
Kaposi sarcoma-associated herpesvirus infection
ecb05170
Human immunodeficiency virus 1 infection
ecb05171
Coronavirus disease - COVID-19
ecb05200
Pathways in cancer
ecb05203
Viral carcinogenesis
ecb05205
Proteoglycans in cancer
ecb05206
MicroRNAs in cancer
ecb05207
Chemical carcinogenesis - receptor activation
ecb05208
Chemical carcinogenesis - reactive oxygen species
ecb05210
Colorectal cancer
ecb05211
Renal cell carcinoma
ecb05212
Pancreatic cancer
ecb05213
Endometrial cancer
ecb05214
Glioma
ecb05215
Prostate cancer
ecb05216
Thyroid cancer
ecb05218
Melanoma
ecb05219
Bladder cancer
ecb05220
Chronic myeloid leukemia
ecb05221
Acute myeloid leukemia
ecb05223
Non-small cell lung cancer
ecb05224
Breast cancer
ecb05225
Hepatocellular carcinoma
ecb05226
Gastric cancer
ecb05230
Central carbon metabolism in cancer
ecb05231
Choline metabolism in cancer
ecb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100057701 (MAPK1)
04012 ErbB signaling pathway
100057701 (MAPK1)
04014 Ras signaling pathway
100057701 (MAPK1)
04015 Rap1 signaling pathway
100057701 (MAPK1)
04350 TGF-beta signaling pathway
100057701 (MAPK1)
04370 VEGF signaling pathway
100057701 (MAPK1)
04371 Apelin signaling pathway
100057701 (MAPK1)
04668 TNF signaling pathway
100057701 (MAPK1)
04066 HIF-1 signaling pathway
100057701 (MAPK1)
04068 FoxO signaling pathway
100057701 (MAPK1)
04072 Phospholipase D signaling pathway
100057701 (MAPK1)
04071 Sphingolipid signaling pathway
100057701 (MAPK1)
04024 cAMP signaling pathway
100057701 (MAPK1)
04022 cGMP-PKG signaling pathway
100057701 (MAPK1)
04151 PI3K-Akt signaling pathway
100057701 (MAPK1)
04150 mTOR signaling pathway
100057701 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100057701 (MAPK1)
04148 Efferocytosis
100057701 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
100057701 (MAPK1)
04210 Apoptosis
100057701 (MAPK1)
04218 Cellular senescence
100057701 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100057701 (MAPK1)
04520 Adherens junction
100057701 (MAPK1)
04540 Gap junction
100057701 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
100057701 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100057701 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100057701 (MAPK1)
04613 Neutrophil extracellular trap formation
100057701 (MAPK1)
04620 Toll-like receptor signaling pathway
100057701 (MAPK1)
04621 NOD-like receptor signaling pathway
100057701 (MAPK1)
04625 C-type lectin receptor signaling pathway
100057701 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
100057701 (MAPK1)
04660 T cell receptor signaling pathway
100057701 (MAPK1)
04658 Th1 and Th2 cell differentiation
100057701 (MAPK1)
04659 Th17 cell differentiation
100057701 (MAPK1)
04657 IL-17 signaling pathway
100057701 (MAPK1)
04662 B cell receptor signaling pathway
100057701 (MAPK1)
04664 Fc epsilon RI signaling pathway
100057701 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
100057701 (MAPK1)
04062 Chemokine signaling pathway
100057701 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
100057701 (MAPK1)
04929 GnRH secretion
100057701 (MAPK1)
04912 GnRH signaling pathway
100057701 (MAPK1)
04915 Estrogen signaling pathway
100057701 (MAPK1)
04914 Progesterone-mediated oocyte maturation
100057701 (MAPK1)
04917 Prolactin signaling pathway
100057701 (MAPK1)
04921 Oxytocin signaling pathway
100057701 (MAPK1)
04926 Relaxin signaling pathway
100057701 (MAPK1)
04935 Growth hormone synthesis, secretion and action
100057701 (MAPK1)
04919 Thyroid hormone signaling pathway
100057701 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
100057701 (MAPK1)
04916 Melanogenesis
100057701 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100057701 (MAPK1)
04270 Vascular smooth muscle contraction
100057701 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100057701 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
100057701 (MAPK1)
04725 Cholinergic synapse
100057701 (MAPK1)
04726 Serotonergic synapse
100057701 (MAPK1)
04720 Long-term potentiation
100057701 (MAPK1)
04730 Long-term depression
100057701 (MAPK1)
04723 Retrograde endocannabinoid signaling
100057701 (MAPK1)
04722 Neurotrophin signaling pathway
100057701 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
100057701 (MAPK1)
04380 Osteoclast differentiation
100057701 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
100057701 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100057701 (MAPK1)
05206 MicroRNAs in cancer
100057701 (MAPK1)
05205 Proteoglycans in cancer
100057701 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
100057701 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
100057701 (MAPK1)
05203 Viral carcinogenesis
100057701 (MAPK1)
05230 Central carbon metabolism in cancer
100057701 (MAPK1)
05231 Choline metabolism in cancer
100057701 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100057701 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
100057701 (MAPK1)
05212 Pancreatic cancer
100057701 (MAPK1)
05225 Hepatocellular carcinoma
100057701 (MAPK1)
05226 Gastric cancer
100057701 (MAPK1)
05214 Glioma
100057701 (MAPK1)
05216 Thyroid cancer
100057701 (MAPK1)
05221 Acute myeloid leukemia
100057701 (MAPK1)
05220 Chronic myeloid leukemia
100057701 (MAPK1)
05218 Melanoma
100057701 (MAPK1)
05211 Renal cell carcinoma
100057701 (MAPK1)
05219 Bladder cancer
100057701 (MAPK1)
05215 Prostate cancer
100057701 (MAPK1)
05213 Endometrial cancer
100057701 (MAPK1)
05224 Breast cancer
100057701 (MAPK1)
05223 Non-small cell lung cancer
100057701 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100057701 (MAPK1)
05170 Human immunodeficiency virus 1 infection
100057701 (MAPK1)
05161 Hepatitis B
100057701 (MAPK1)
05160 Hepatitis C
100057701 (MAPK1)
05171 Coronavirus disease - COVID-19
100057701 (MAPK1)
05164 Influenza A
100057701 (MAPK1)
05163 Human cytomegalovirus infection
100057701 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100057701 (MAPK1)
05165 Human papillomavirus infection
100057701 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
100057701 (MAPK1)
05135 Yersinia infection
100057701 (MAPK1)
05133 Pertussis
100057701 (MAPK1)
05152 Tuberculosis
100057701 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100057701 (MAPK1)
05140 Leishmaniasis
100057701 (MAPK1)
05142 Chagas disease
100057701 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100057701 (MAPK1)
05020 Prion disease
100057701 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
100057701 (MAPK1)
09165 Substance dependence
05034 Alcoholism
100057701 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100057701 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100057701 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
100057701 (MAPK1)
04934 Cushing syndrome
100057701 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100057701 (MAPK1)
01524 Platinum drug resistance
100057701 (MAPK1)
01522 Endocrine resistance
100057701 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100057701 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ecb03036
]
100057701 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ecb04147
]
100057701 (MAPK1)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
100057701 (MAPK1)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
100057701 (MAPK1)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
100057701 (MAPK1)
Exosome [BR:
ecb04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
100057701 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
RIO1
Haspin_kinase
Choline_kinase
FTA2
Kinase-like
Kdo
Motif
Other DBs
NCBI-GeneID:
100057701
NCBI-ProteinID:
XP_005612439
Ensembl:
ENSECAG00000010551
VGNC:
19954
UniProt:
A0A5F5PIW7
LinkDB
All DBs
Position
8:complement(5463317..5568728)
Genome browser
AA seq
327 aa
AA seq
DB search
MYPEKSSSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAP
TIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPS
NLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWS
VGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKV
PWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDM
ELDDLPKEKLKELIFEETARFQPGYRS
NT seq
984 nt
NT seq
+upstream
nt +downstream
nt
atgtatccagagaaaagcagctctgcttatgataatgtcaacaaagttcgagtagctatc
aagaaaatcagtccttttgagcaccagacctactgccagagaaccctgagggagataaaa
atcttactgcgcttcagacatgagaacatcattggaatcaatgatattattcgagcgcca
accatcgagcaaatgaaagatgtatatatagtacaggacctcatggaaacggatctctac
aaactcttgaagacccaacacctcagcaacgaccatatctgctattttctttaccagatc
ctcagagggttaaaatatatccattcagctaacgtactgcatcgtgacctcaaaccttcc
aacctgctgctcaataccacctgtgatctcaagatctgtgactttggcttggcccgtgtt
gcagatccggaccatgatcacacagggttcctgacggagtatgtagccacgcgttggtac
agggctccagaaattatgttgaattccaagggctataccaagtccattgatatttggtct
gtaggctgcattctggcagagatgctctccaacaggcctatcttcccggggaagcattat
cttgaccagctgaaccacattctgggtattcttggatccccatcacaggaagacctgaat
tgtataataaatttaaaagctagaaactatttgctttctcttccacacaaaaataaggtg
ccatggaacaggctgttcccaaatgctgactccaaagctctcgacttgctggacaaaatg
ttgacattcaaccctcacaagaggatcgaagtagagcaggctctggcccacccgtacctg
gagcagtactatgacccgagtgacgagcccatcgctgaagcaccattcaagtttgacatg
gaattggatgatttgcccaaggaaaagctcaaagaactcatttttgaagagactgctaga
ttccagccaggatacagatcttaa
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integrated database retrieval system