Equus caballus (horse): 100059954 Help Entry 100059954         CDS       T01058                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism ecb  Equus caballus (horse) Pathway ecb04022   cGMP-PKG signaling pathway ecb04068   FoxO signaling pathway ecb04140   Autophagy - animal ecb04152   AMPK signaling pathway ecb04211   Longevity regulating pathway ecb04213   Longevity regulating pathway - multiple species ecb04910   Insulin signaling pathway ecb04920   Adipocytokine signaling pathway ecb04923   Regulation of lipolysis in adipocytes ecb04930   Type II diabetes mellitus ecb04935   Growth hormone synthesis, secretion and action ecb05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:ecb00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100059954 (IRS4)    04022 cGMP-PKG signaling pathway     100059954 (IRS4)    04152 AMPK signaling pathway     100059954 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100059954 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100059954 (IRS4)    04923 Regulation of lipolysis in adipocytes     100059954 (IRS4)    04920 Adipocytokine signaling pathway     100059954 (IRS4)    04935 Growth hormone synthesis, secretion and action     100059954 (IRS4)   09149 Aging    04211 Longevity regulating pathway     100059954 (IRS4)    04213 Longevity regulating pathway - multiple species     100059954 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100059954 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100059954 (IRS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH_11 PH_8 PH Motif Other DBs NCBI-GeneID:  100059954 NCBI-ProteinID:  XP_023489198 VGNC:  19142 LinkDB All DBs Position X:complement(90058938..90075004) Genome browser AA seq 1266 aa AA seqDB search MASCSSARDQATRRGRAAAAATAAALAAVATTPLLSSGTPTALIGTGSSCPGAMWLSTAT GSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV AENESEQESWYLLLSRLILESKRRRCGTPGAQPDGEPAALAAAAAAEPPFYKDVWQVVVK PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH LDVLPLEPSGWLRRSRFEQFCHLRAIGDGEDEMLLTRRYITPSEPVHPSRRGRLYVPRAR RSRRAVSVPASCFRHLAPNPVRAPRPAEAPNLGTCLSPEASGSGSGNSGEEGNPEGKEGQ EGNGGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSQGSDGNQCSGGGQGSGGGQGSSGGQG SGGQGAGGNQCSGDGQGTTGGHGSGGGQGAGGGHGSGSGQGPGDGHGSGGGKNSGGGKGS GSGKGSDGNGERGKSLKKRSYFGKLTQSKQQQMPPPPPSPPPPPPAGATGGKGKSGGRFR LYFCADRGATKERKEAKEVKDVESPEDAARGPHRVRAFDEDEDDPYVPMRPGVAAPLASS SDYMPMAPQNVSASEKRHSRSPFEDSRGYMMMFPRVSPPSAPNPPKAPDPEKEDDSKDND SDSDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPLQSSPLGQSDHSEYVPMLPG KLLGKGLDKEASSQGDPKDAASKPSVERSFSKPGDGGSPSKPSDESPPKIKAKRPNRLSF ITKGNKIKPKPQKPTREQREADSSSGYVNVDFTKRDSNTPAPSTQGLPGLWGIIADPRRS VFSNYVNVEFGVPFPNPGNDLSHLLRAIPGANPLFLDGARWPLLPLPPSATGSNANEEEG DYIEVMFNPAMIPAVPFADRAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARL LLEEELERRRPQSRSQGFFASTRAAVSAFPTDSLERDLSASLASAAALAAAPTLGVGRAL AAASALAAAPGIGAAASGFEAAAGFDSASVRWFQPVANAADAEAVMGAQDVASGSNPRAQ NPSSDLDGDEDGTGEAAAAAAVPPTPPRRQMPRPPEQEDSDDDDDTYVRMDFARSDNKKF DSPRRE NT seq 3801 nt NT seq  +upstreamnt  +downstreamnt atggcgagttgctcctctgctcgcgaccaagcgacaaggagagggagagctgcagcagcg gcaacagcagcagctctagctgcggtggcgaccaccccacttctttcctcgggaaccccg accgcactcattgggaccgggtcgtcctgtccgggagccatgtggctctctacggccact ggctcccggtcagactccgagtccgatgaggaggacctccccgtcggggacgaagtctgc aaacgcggatacctgcggaagcagaagcatgggcacaggcgctacttcgtgctcaaactc gagaccgccgacgccccagctcggctggaatactacgaaaatgccaggaagttccggcac agtgtccgcgccgcggcggctgcagcagcggcggccgcctctggcgccgcggtccccgcg ctcatcccaccgcggcgcgtgatcaccttgtaccagtgcttctcggtgagccagcgagcc gacgcaaggtaccgacacctcattgcccttttcacccaagacgagtatttcgcgatggtg gccgagaacgagtcggagcaagagagctggtacttgctgctcagccgcctcatcctcgag agcaagcgccgccgctgcggcacgcccggcgcgcagccggatggagagccggcggcgctg gcggctgcagcggcggcggagccacccttctacaaagatgtgtggcaggtagtagtcaaa cccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtcttaccgac gaggaggttgtgtttgtgaggctgaataccgaggtggccagcgtggttgtccagctcctg agcatccgtcgctgcgggcactcagagcagtatttcttcttggaagtcggcaggtccacc gtcatcggtccgggggaactctggatgcaggttgatgactgtgtagtggcccaaaacatg catgagctgtttttggagaagatgagagccttgtgtgcagacgagtacagagcccgctgc cgcagctacagcatcagcatcggcgcccacctgttaaccctgctgtccgctaggaggcac ctggacgtgctgccgctggagcccagcggctggctcagaaggtcccgctttgagcagttt tgccacctcagggccatcggtgacggggaagacgaaatgctcctcaccaggcgctacata acgcccagcgagcctgtacacccctcgaggagaggaagactgtacgtgcccagagcgcgc aggtccaggagagcagtttcagtgccagccagctgttttcgccacttagcacccaacccg gtgcgtgctccgcgccctgcggaagcccccaaccttggaacttgcctgtctccagaagca tctggttctggctctggtaactctggggaggaaggcaatcctgagggcaaagagggtcag gaaggaaatggaggcgactacatgcccatgaacaattggggctcaggaaatggccgaggc tcaggaggtggccagggctcaagtggccaaggctccagtagccagggctcagatggaaac cagtgctcaggtggagggcagggctccggaggtggccagggctcaagtggcggccagggg tcagggggccaaggtgcaggaggaaaccagtgctcaggagatggccaaggcaccacaggt ggtcatggctcaggtggtggccagggagctggaggtgggcacggctcaggcagtggccag ggacctggagatggccatggctcaggcggcggcaagaactctggagggggcaaaggctca ggaagtgggaaaggctctgatggcaatggtgaacgtggaaaatctctgaagaaaagatcc tactttggcaaattaactcaaagcaagcaacagcaaatgccaccacctccaccatctcca cctccacctccgccagctggagcaacaggtggaaaagggaagtccgggggaaggttccga ctttatttttgtgctgacagaggagccacaaaagagcgcaaagaagccaaagaagtcaaa gatgtagagagccccgaagatgcagctcggggtccccacagagtcagagcttttgatgaa gatgaggatgacccatacgtgccaatgaggccaggggtggctgcccctctcgcaagctcc agtgattatatgccaatggctcctcaaaacgtctctgcttcagaaaagcgccattctcga tcaccttttgaagattcaagagggtacatgatgatgtttcccagggtgagcccaccctct gccccaaatcctccaaaagcaccagatcctgagaaagaggatgactcaaaggataacgac agcgacagtgactacatgtttatggctcctggagccggtgcaattccaaaaaaccccaga aatcctcagggaggctcttcctccaaaagttggagctcctacttctctctgccaaatcca cttcagagctccccgttgggccagagtgaccacagtgagtatgttccaatgttacctggc aaattactggggaagggcctggacaaagaagcctcatctcagggggaccccaaagatgca gcttcaaagccttcagttgagcggtcattctcaaagcctggagatggggggtcaccttca aagccttcagatgagagcccccccaagatcaaggctaagagacctaaccgactttctttt attacaaaaggaaataaaatcaagccaaaaccacaaaagcccacacgtgagcagagagaa gctgacagctctagtggctacgtcaacgttgacttcactaaaagagatagcaatacacca gcaccctctactcaaggactgccaggtttgtggggcataattgctgaccccagacggtca gtcttttctaattacgtgaatgttgagttcggagtgccatttccaaatccaggaaacgac ctctcacatcttttaagagctattccaggtgccaaccctctctttctggacggtgctagg tggccacttctgcctcttcctcccagtgctacagggagcaatgctaatgaggaagagggg gactacattgaagtgatgttcaacccagcaatgataccagccgtgccttttgctgaccgt gccattcgctatgatgctgaaacaggtcgaatctatgtggtcgacccattttctgagtgc tgtatggacatttctctttctcccagccgatgctctgaaccaccacctgtagctaggctg ctgctggaagaagagctagagagaagacgcccacaaagccgttcgcaaggtttctttgca tccaccagagccgctgtctcagctttcccaaccgacagcctggagagagacctctccgcc tccttagcctcggccgccgctttggccgctgcgccaaccttaggcgtgggccgggcttta gccgccgcctccgccctcgctgcggccccgggcatcggcgcagctgcctcgggcttcgag gccgccgctggatttgactccgcctccgtccgctggttccaacctgttgctaatgctgct gatgccgaagcagtaatgggggcccaagacgttgccagtggctcgaaccctagagcccaa aacccatcttcagaccttgacggagatgaggacgggactggcgaggctgcggctgcagct gccgtcccccccacaccacctcgccgccagatgccgagaccccccgagcaagaagattct gacgacgacgacgacacatacgtgagaatggacttcgccagatctgacaacaagaagttc gactctccccgaagagagtga

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