KEGG   Equus caballus (horse): 100064102
Entry
100064102         CDS       T01058                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00480  Glutathione metabolism
ecb00980  Metabolism of xenobiotics by cytochrome P450
ecb00982  Drug metabolism - cytochrome P450
ecb00983  Drug metabolism - other enzymes
ecb01100  Metabolic pathways
ecb01524  Platinum drug resistance
ecb05200  Pathways in cancer
ecb05204  Chemical carcinogenesis - DNA adducts
ecb05207  Chemical carcinogenesis - receptor activation
ecb05208  Chemical carcinogenesis - reactive oxygen species
ecb05225  Hepatocellular carcinoma
ecb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100064102 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100064102 (MGST1)
   00982 Drug metabolism - cytochrome P450
    100064102 (MGST1)
   00983 Drug metabolism - other enzymes
    100064102 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100064102 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    100064102 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    100064102 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100064102 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100064102 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100064102 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100064102 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ecb02000]
    100064102 (MGST1)
Enzymes [BR:ecb01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100064102 (MGST1)
Transporters [BR:ecb02000]
 Other transporters
  Pores ion channels [TC:1]
   100064102 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 100064102
NCBI-ProteinID: XP_001501941
Ensembl: ENSECAG00000020763
VGNC: 20166
UniProt: F6U8C2
LinkDB
Position
6:44833696..44857132
AA seq 155 aa
MVGLTQVMENEAFMAFASYATIILSKMMFMSTATAFCRLTRKVFANPEDCAGFGKGENAK
KYLRTDDRVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTAILHFRIFVGARIYHTIA
YLTPLPQPNRALAFFVGYGVTLSMAYRLLTGRLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggttggcctcacccaggtaatggaaaatgaagcattcatggcttttgcctcctatgca
acgattattctttcaaaaatgatgttcatgagtactgcaactgcattctgtagattgaca
agaaaggtttttgccaacccagaggactgtgcaggttttggcaagggagaaaatgccaag
aagtatcttcggacagatgacagagtggaacgtgtacgaagagcccacctgaatgacctt
gaaaatattgtgccatttcttggtattggccttctatattccttgagtggtccagatctc
tctacagccatcctgcacttcagaatctttgttggagcacggatctaccacacgattgca
tatttgacaccccttccccagccaaatcgtgctttggctttttttgtcggatatggagtt
actttgtcaatggcttacaggctgttgacgggtagattgtacctgtaa

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