Equus caballus (horse): 100069715
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Entry
100069715 CDS
T01058
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04012
ErbB signaling pathway
ecb04014
Ras signaling pathway
ecb04110
Cell cycle
ecb04360
Axon guidance
ecb04722
Neurotrophin signaling pathway
ecb05200
Pathways in cancer
ecb05206
MicroRNAs in cancer
ecb05208
Chemical carcinogenesis - reactive oxygen species
ecb05220
Chronic myeloid leukemia
ecb05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100069715 (ABL1)
04014 Ras signaling pathway
100069715 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100069715 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100069715 (ABL1)
09158 Development and regeneration
04360 Axon guidance
100069715 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100069715 (ABL1)
05206 MicroRNAs in cancer
100069715 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
100069715 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100069715 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
100069715 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100069715 (ABL1)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100069715 (ABL1)
Protein kinases [BR:
ecb01001
]
Non-receptor tyrosine kinases
ABL family
100069715 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
100069715
NCBI-ProteinID:
XP_023484920
Ensembl:
ENSECAG00000014981
VGNC:
49495
LinkDB
All DBs
Position
25:34048784..34187509
Genome browser
AA seq
1149 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFSTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSERPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGAAGP
LLQAPELPTKTRTSRRAAEHKDSTDGAETPHPKGPGETDPLDHEPAVSPLLPRKERGPQD
GGLNEDERLLPKDKKTNLFSALIKKKKKTAPAPPKRSSSFREMDGQPERKVAGEEEGREV
SNGALALAPSDTPEPAKSPKPSSGAGVPNGAFRESGGAGFRSPHLWKKSSTLTSSRLAAS
EEENGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA
LPRKRASETRSDQVTRGTVTPPPRLVKKTEEAVDEVLRDAAESSPGSSPPSLTPKLLRRQ
VVVAPSSGLPHKEEAGKSSAFGTPAAEPVPPTSRAGPGASGGTSKAPNEESRVRRHKPSS
ESPGRDKGKLSKLKPAPPPPPPASVGKAGKPSQSPSQEAAGEAGACGKAKPTALVVDAVN
SDTAKPSQLGEGVKKAVLPAVPKSQSSTKPAGTPTSPVPAPSVLPSASSTLAGDQPSSTA
FIPLISTRVSLRKTRQPPERIASGAITKGVVLDGTEALCLAISKNSEQMASHSAVLEAGK
NLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSV
KEISDIVQR
NT seq
3450 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccaaagaaggccaagtttgcctgccctg
cactttatcaaaggagcggggaagaaggaatcatcgaggcatgggggtccacactgcaat
gtttttgtggaacatgaagcccttcaaaggccagtagcatctgacttcgagccccaaggt
ctcagtgaagcagctcgttggaactccaaggaaaaccttcttgctggtcccagtgaaaat
gaccccaacctttttgttgcactgtatgattttgtggccagtggggataacactctaagc
ataactaaaggtgaaaagctccgggtcttaggctacaatcacaatggggaatggtgtgaa
gcccaaaccaaaaatggccaagggtgggtcccaagcaactacatcacaccagtcaacagt
ctggagaagcattcctggtaccacggacccgtgtcccgcaatgccgccgaatacctactg
agcagtggaatcaacggcagcttcttggtgcgggagagcgagagcagccctggccagagg
tccatctcactgagatacgaagggagggtgtaccactacaggatcaacactgcttctgat
ggcaagctctacgtctcctcagagagccgcttcagcactttggccgagctggttcaccat
cactcgactgtggcagacgggctcatcaccaccctgcattacccagcccccaagcgcaac
aagcccactgtctacggcgtgtcccccaactatgacaagtgggagatggagcgcacggac
atcaccatgaagcacaagctgggaggaggccagtacggggaggtgtacgaaggcgtgtgg
aagaagtacagcctgacggtggccgtgaagaccctgaaggaggacaccatggaggtggaa
gagttcctgaaggaagctgcagtgatgaaggagatcaaacaccctaatttagtgcagctt
ctcggggtctgcacccgggagcccccgttctatataatcactgagttcatgacctatgga
aacctgttggattacctgagggagtgtaaccggcaggaggtgaatgctgtcgtgctgctg
tacatggccacgcagatctcgtcagccatggagtacctggagaagaaaaacttcatccac
agagacctcgctgcccggaactgcctggtaggggaaaaccacctggtgaaggtggctgat
tttggcctgagcaggttaatgacaggggatacctacacagcccacgccggggccaagttc
cctatcaaatggaccgcacctgagagcctggcctacaacaagttctccatcaagtccgac
gtctgggcatttggagtgttgctttgggaaattgctacctatggcatgtcaccttaccca
ggaattgacctgtcccaggtgtatgagctgctggagaaagactaccgcatggagcgcccg
gaaggctgcccagagaaggtctacgaactcatgcgagcatgttggcagtggaatccctct
gagcggccctcctttgctgaaatccaccaagcttttgaaacaatgttccaggagtccagc
atctcagatgaagtggagaaggaactggggaagaaaggagtgcgaggggctgcaggtcct
ttgctgcaggccccagagctgcccaccaagacaagaacctccaggagagctgcagaacac
aaagactccaccgacggggctgagaccccccaccccaagggcccaggggagactgatcct
ctggaccacgagcctgctgtgtctccgttgctccctcgaaaagagcgaggtccccaggat
ggtggcttaaatgaagatgaacgccttctccccaaagacaaaaagaccaacttgttcagt
gccttgatcaagaagaagaagaaaacagccccagcccctcccaaacgcagcagctccttc
cgggagatggacggccagccggagcgcaaggtggccggggaggaagagggccgggaggtt
agcaacggcgccctagctctcgcaccctcggacacacccgagccagccaagtccccaaag
cccagcagcggggctggtgtccctaatggagccttccgggagtcggggggcgcaggcttc
cggtctccacacctatggaaaaagtctagcacgctgaccagtagccgattagcagccagt
gaagaggagaatggcggcagctccagcaagcgcttcctgaggtcctgctctgcctcctgt
gtgccccatggggccaaggacacagagtggaggtctgtcacactgcctcgggatctgcag
tccacaggaagacagtttgactcgtccacatttggagggcacaaaagtgagaagccagct
ctgcctcgaaagcgggcaagtgagaccaggtctgaccaggtgaccagaggcacagtgacc
cccccgcccaggctggtgaagaagaccgaggaagccgtggatgaggtcttaagagacgca
gcagagtccagcccgggctccagccctcccagtctgactccaaaactcctccgtaggcag
gtcgtggtggctccttcctctggccttccccacaaggaagaggccgggaagtccagtgcc
ttcgggacgcctgcagctgagccggtgccccccaccagcagagcggggccaggtgcatct
ggagggaccagcaaggcccccaacgaggagtccagagtgaggaggcacaagccctcctcc
gagtccccagggagagacaaggggaagttgtccaagctcaaacccgccccaccaccccca
ccaccagcctctgttgggaaagccgggaagccctctcagagcccgagccaggaagcagcc
ggggaggcaggtgcctgtggaaaagcaaaacccacggccctggttgtggatgctgtgaac
agtgacactgccaaacccagccagctgggagagggcgtgaaaaaggccgtgctcccagct
gtgccaaagtcgcagtcatccaccaaaccagcagggaccccgaccagcccagtccccgct
ccctctgtgttgccgtcagcatcctccaccctggcaggggaccagccgtcctccaccgcc
ttcattcctctcatatcgactcgcgtgtctcttcggaaaacccgccagcctccggagcga
attgccagtggtgccatcaccaagggtgtggtcctggatggcactgaggccttgtgcctt
gctatctccaagaactctgagcagatggccagccatagcgctgtgctggaagctggcaaa
aacctctacacattctgtgtgagctacgtggattccatccagcaaatgaggaataaattc
gccttccgcgaggccatcaacaaactggagaataacctccgggagcttcagatctgcccg
gcgacagcggggagtggcccagcggccactcaggacttcagcaaactcctcagctccgtg
aaagagatcagtgacatcgtgcagaggtag
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