Equus caballus (horse): 100072571
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Entry
100072571 CDS
T01058
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X2
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00760
Nicotinate and nicotinamide metabolism
ecb01100
Metabolic pathways
ecb04068
FoxO signaling pathway
ecb04148
Efferocytosis
ecb04152
AMPK signaling pathway
ecb04211
Longevity regulating pathway
ecb04213
Longevity regulating pathway - multiple species
ecb04218
Cellular senescence
ecb04310
Wnt signaling pathway
ecb04922
Glucagon signaling pathway
ecb04936
Alcoholic liver disease
ecb05031
Amphetamine addiction
ecb05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
100072571 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100072571 (SIRT1)
04068 FoxO signaling pathway
100072571 (SIRT1)
04152 AMPK signaling pathway
100072571 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100072571 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
100072571 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100072571 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
100072571 (SIRT1)
04213 Longevity regulating pathway - multiple species
100072571 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100072571 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
100072571 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100072571 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ecb03036
]
100072571 (SIRT1)
03029 Mitochondrial biogenesis [BR:
ecb03029
]
100072571 (SIRT1)
Enzymes [BR:
ecb01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
100072571 (SIRT1)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
100072571 (SIRT1)
Mitochondrial biogenesis [BR:
ecb03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
100072571 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
Motif
Other DBs
NCBI-GeneID:
100072571
NCBI-ProteinID:
XP_014588585
VGNC:
51676
UniProt:
A0A9L0T095
LinkDB
All DBs
Position
1:56785997..56812489
Genome browser
AA seq
446 aa
AA seq
DB search
MCLCSGRKTILEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCH
GSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFH
RAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCD
VIINELCHRLGGEYAKLCCNPIKLSEITEKPPRTQRELAHLSELPPTPLNISEDSSSPER
TSPPDSSVIVTLLDQATKSNVDDPDVSKSKDCMEEKSQEVQTSTRSFQSVTERLGSPYLK
NVGSDTGEKNERTSVAEAVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDS
EEDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDDADVNERAGGTGFRADG
SDQEAVNETISTKQEATDINYSSNKS
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atgtgcctgtgcagtggaaggaaaacaattttggaaatatatcctggacagttccagcca
tctctctgtcacaaattcatagctttgtcagataaggaaggaaaactacttcgcaactat
actcagaacatagatacactggaacaggttgcaggaatccaaaggataattcagtgtcac
ggttcctttgcaacagcgtcttgcctgatttgtaaatacaaagttgactgtgaagctgta
cgaggagatatttttaatcaggtggttcctcgatgtcccaggtgcccagctgatgaacca
cttgctatcatgaaaccagagattgttttttttggtgaaaatttaccagaacagtttcat
agagccatgaaatatgacaaagatgaagttgatctcctcatcgttattgggtcttccctg
aaagtaagaccagtagcactaattccaagttccataccccatgaagtgcctcagatatta
attaatagggaacctttgcctcatctgcattttgatgtagagcttcttggagactgtgat
gtcataattaatgaattgtgtcataggttaggtggtgaatatgccaaactttgctgcaac
cctataaagctttcagaaattactgaaaaacctccacgaacacaaagagagttggctcat
ttgtcagaattgccacccacacctcttaatatttcagaagactcaagttcaccagaaaga
acttcaccaccagattcgtccgtgattgtcacacttttagaccaagcaacaaagagtaat
gttgatgatccagatgtgtccaaatcaaaagattgtatggaagaaaaatcacaggaagta
cagacatctactaggagctttcaaagtgttactgaacggttgggaagtccgtatttgaag
aatgttggctctgatactggggagaaaaatgaaagaacttcagttgctgaagcagtaaga
aagtgctggccagctagactcgcaaaggagcagattagtaaacggcttgatggtaatcag
tatctgtttttaccaccaaatcgttacattttccatggcgctgaggtatattcagactct
gaagaagatgtcttatcctctagctcttgtggcagtaatagtgatagtggaacatgccag
agtccaagtttagaagaacccatggaggatgaaagtgagattgaagaattctacaatggt
ttggaagatgatgctgatgttaatgagagagctggaggaactggatttagagctgatgga
agtgatcaagaggcagttaatgaaactatatccacgaaacaggaagcaacggacattaac
tattcatcaaacaaatcataa
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