Equus caballus (horse): 100073186
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Entry
100073186 CDS
T01058
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01524
Platinum drug resistance
ecb04010
MAPK signaling pathway
ecb04071
Sphingolipid signaling pathway
ecb04141
Protein processing in endoplasmic reticulum
ecb04210
Apoptosis
ecb04530
Tight junction
ecb04668
TNF signaling pathway
ecb04714
Thermogenesis
ecb04722
Neurotrophin signaling pathway
ecb04932
Non-alcoholic fatty liver disease
ecb04936
Alcoholic liver disease
ecb05010
Alzheimer disease
ecb05012
Parkinson disease
ecb05014
Amyotrophic lateral sclerosis
ecb05016
Huntington disease
ecb05017
Spinocerebellar ataxia
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05208
Chemical carcinogenesis - reactive oxygen species
ecb05417
Lipid and atherosclerosis
ecb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100073186 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100073186 (MAP3K5)
04668 TNF signaling pathway
100073186 (MAP3K5)
04071 Sphingolipid signaling pathway
100073186 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
100073186 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
100073186 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100073186 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
100073186 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100073186 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
100073186 (MAP3K5)
05012 Parkinson disease
100073186 (MAP3K5)
05014 Amyotrophic lateral sclerosis
100073186 (MAP3K5)
05016 Huntington disease
100073186 (MAP3K5)
05017 Spinocerebellar ataxia
100073186 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
100073186 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100073186 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
100073186 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100073186 (MAP3K5)
04932 Non-alcoholic fatty liver disease
100073186 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100073186 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100073186 (MAP3K5)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
100073186 (MAP3K5)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: STE group
STE11 family
100073186 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
100073186
NCBI-ProteinID:
XP_023506950
Ensembl:
ENSECAG00000024860
VGNC:
19939
LinkDB
All DBs
Position
10:complement(83230586..83411018)
Genome browser
AA seq
1363 aa
AA seq
DB search
MSGEAAEGLTFSVPPCALAEGGGSRRGAAAEGEEGARLPPAPPGSFWNVESAAAPVPPCC
GSAPRSRGSGGSGGGGRRPTVAYVINEASQGPLAVAESEALQSLREACEAAGAALETLHF
GKLDFGETAVLDRFYNADVAVVEMSDAFRQPSLFYHLGVRESCSMASNIILYCDTNSDSL
QSLKEIIFQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLP
LVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTAD
IVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKAL
DIMIPLVQSEGQVASDVYCLMGRIYKDMFLDSNFMDTESRDHGASWFKKAFESEPTLQSG
INYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHV
RVIQASEKLFKLKTPAWYLRSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKT
DVAVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGV
SISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRNTEEGDCEADSLE
YDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHL
KHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLK
YLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIID
QGPRGYGRAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEVPESMSAEAK
AFILKCFEPDPDKRDGANDLLLDEFLKVSGKKKKTQPKLSALAAGSNAEYLRSISLPVPV
LVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDGKGIRTLFLGIPDENFEDHSAP
PSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMEALAQGAEEPKLKWEHITTLI
ASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHW
MFALDSIIRKAVQAAITILVPELRPHFSLASESDTADQDDLEAEDDHEEQPSSQTVQRPH
VVLDDAVATSGVSTLSSTVSHDSQSAHRSLTVQLGRMKIETNRLLEELVQKEKELQALLH
QAIEEKDQEIKHLKLKSQPIDIPGLPVCHLNSPGTNTEDSELTEWLRENGADEDTISRFL
AEDYSLVDVLYYVTRDDLKCLRLRGGVLCTLWKAITDFRDKQT
NT seq
4092 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcgaggcggccgagggcctcaccttctccgtgccgccctgcgccctcgccgag
ggcggcggcagccggcggggggcggcggccgagggcgaggagggcgcgcgcctgccgccg
gcgccgccgggcagcttctggaacgtggagagcgccgccgccccggtccccccctgctgc
ggcagcgccccccggagccggggcagcggcggcagcggcggcggcggccggcgccccacg
gtggcctatgtgatcaacgaggcgagccaggggccgctggccgtggccgagagcgaggcg
ctgcagagcctgcgggaggcgtgcgaggcggcgggcgccgccctggagaccctgcacttc
gggaagctggacttcggggagacggcggtgctggaccggttctacaacgcagacgtcgcc
gtggtggagatgagcgacgccttccggcagccgtccttgttctaccacctcggggtgagg
gagagctgcagtatggccagcaacatcatcctctactgcgacaccaactcagactccctg
cagtcgctcaaggaaatcattttccagaagaatactatgtgcaccgggaactacacgttc
gtcccctacatgatcacgccgcacaacaaggtctactgctgcgacagcagcttcatgaag
gggctcacggagctcatgcagcccaacttcgagctgctccttgggcccatctgcttacct
cttgtggatcgtttcattcagcttctgaaggtggcacaagcaagttccagccagtatttc
cgggaatctatactcaatgatatcaggaaagctcgtaatttatacactggtaaagaactg
gcagctgaattggcaagaattcgtcagcgagtagataatattgaagtcttgacagcagac
attgtcatcaatctgttgctttcctacagagatatccaggactacgactcgattgtgaag
ctggtggagacactggaaaagctgcccacctttgacctggcctcccatcaccacgtgaag
ttccattatgcgttcgctctgaacaggagaaatctccctggagacagagcgaaggctctt
gacatcatgatcccgctggtgcagagcgaagggcaggtggcttccgacgtgtactgcctc
atgggtcgaatctacaaagacatgtttttggactctaatttcatggacactgaaagtaga
gaccatggagcttcttggttcaaaaaggcatttgaatctgagccaacactacagtcagga
attaattatgcggtcctcctcctggcagctgggcaccagtttgaatcttcctttgagctc
cggaaagttggcgtgaagctcagcagccttctggggaaaaagggaaacttggaaaagctc
cagagctactgggaagtcgggtttttcctgggcgccagtgtcctggccaatgaccacgtg
agagtcattcaggcctctgaaaagcttttcaaactgaagacgccggcatggtacctcagg
tctattgtggagacaattttgatctataagcattttgtgaagctgactacagaacagccg
gtggccaagcaggagctcgtggacttctggatggacttcctcgtcgaggccaccaagacg
gacgtggcggtggtgaggttcccagtattgatcttagaaccaaccaaaatctatcaacct
tcgtatttatctatcaacaatgaagttgaggaaaagacgatatccatttggcacgtgctc
ccagatgacaagaagggcatccatgagtggaatttcagtgcttcgtctgtcaggggagtg
agtatttctaaatttgaagaacgatgctgttttctttatgtgcttcataattctgacgat
ttccaaatctatttctgtacagaacttcactgtaaaaagttttttgagatggtgaacacc
attaccgaagagaagggcaggaacacggaggaaggagactgtgaggctgactccctggag
tatgactacgaatatgatgaaaacggggacagagtggttctaggaaaaggcacttacggg
atcgtctatgcaggccgagacctgagcaaccaagtccgaatcgctattaaggaaatccca
gagagagatagcaggtactcccagcccctacatgaagaaatagcgttgcataagcatctg
aagcacaaaaatatcgtccagtatctgggctctttcagtgagaacggtttcattaaaatc
ttcatggagcaggtcccaggaggaagtctttctgctctccttcgttccaagtggggccca
ttgaaagacaatgagcaaacaattggcttttatacaaagcaaatactcgaaggattaaaa
tacctccatgacaatcagatagttcaccgggatataaagggtgacaatgtgttgattaat
acatacagcggtgttctcaagatctccgacttcgggacatcaaagaggctcgctggcatc
aacccatgcactgaaacctttactggtacccttcagtacatggcaccagagatcatagac
caaggacccaggggttacgggagggctgcagacatttggtctctgggctgcaccatcatc
gaaatggccacgggaaaaccaccattttatgagctgggagagccacaagctgctatgttc
aaggtggggatgttcaaagtccacccggaggtcccggagtccatgtcggcagaggccaag
gcgttcatcctgaagtgttttgaacctgaccctgacaagagagacggcgcgaacgacctg
cttctggatgagttcttaaaagtttcgggcaagaagaagaagacacagccgaagctttcg
gctctggccgccggatcgaatgcagagtacctcaggagcatctccctgccggtgcccgtg
ctggtggaggacacaagcagcagcagcgagtacggctccgtctctcctgacacggagctc
aaggtggaccccttctctttcaagacgagagccaagtcctgcggggagaaagacggaaaa
ggaatacggactctctttctgggcatcccggatgaaaacttcgaagaccacagcgcgccc
ccgtcccctgaggagaaggactccgggttcttcatgctgaggaaggacagcgaacggcgg
gccacgctgcacaggatcctgacggaagaccaggacaaggtcgtgaggaacctgatggag
gctttggctcagggggccgaggaaccaaagctaaagtgggagcacatcacaaccctcatc
gcaagcctcagagaatttgtgagatccaccgaccgaaaaatcatcgccaccacgctgtcg
aagctgaagctggagctggacttcgacagccacggcatcagccaggtccaggtggttctc
tttggtttccaagacgctgtcaataaagttcttcggaatcataacatcaagccacactgg
atgtttgccttagacagtatcatccggaaggcggtgcaggcagccatcaccattctggtt
ccagagctgaggccgcattttagcctcgcatctgagagtgataccgccgatcaagacgac
ttggaggcggaggatgaccatgaggagcagccctcgagtcagactgtccaaagacctcac
gtggtcctcgatgacgccgtggccacctcgggggtgagcacgctcagctccaccgtctcg
cacgactcgcagagcgcccaccgatcgctgaccgtccagcttgggaggatgaagatagaa
acgaacaggttactggaagaattggttcagaaagagaaagaattacaagcactccttcat
caagctattgaagaaaaagaccaagaaattaaacacctgaagcttaagtcccaaccaata
gacattcctgggttgcccgtgtgtcacctgaattctcctgggacaaatactgaagattct
gaacttactgagtggctgagagaaaatggagccgatgaagacaccataagtcggtttttg
gctgaggattattcactagtggatgttctctactatgttacacgtgatgatttaaaatgc
ctgagactaaggggaggggtgctctgcacgctgtggaaggccatcacggactttcgagac
aaacagacttga
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integrated database retrieval system
