Equus caballus (horse): 100146791
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Entry
100146791 CDS
T01058
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04010
MAPK signaling pathway
ecb04020
Calcium signaling pathway
ecb04151
PI3K-Akt signaling pathway
ecb05200
Pathways in cancer
ecb05216
Thyroid cancer
ecb05223
Non-small cell lung cancer
ecb05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100146791 (RET)
04020 Calcium signaling pathway
100146791 (RET)
04151 PI3K-Akt signaling pathway
100146791 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100146791 (RET)
05230 Central carbon metabolism in cancer
100146791 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
100146791 (RET)
05223 Non-small cell lung cancer
100146791 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100146791 (RET)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100146791 (RET)
Protein kinases [BR:
ecb01001
]
Receptor tyrosine kinases (RTK)
RET family
100146791 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100146791
NCBI-ProteinID:
XP_023502504
VGNC:
51660
LinkDB
All DBs
Position
1:complement(71597235..71651734)
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AA seq
1113 aa
AA seq
DB search
MAKATAGAAGLRLLLLLPLLGEAPLGLYFSRDAYWEKLYVDQPAGTPLLYVHALRDVPEE
VPTFRLGQHLYGAYRTRLHENDWIRIQEDTGLLYLNQSLDHSSWEQLSVRNGGFPLLTVY
LQVFLSPTSLREGECQWPGCARVYFSFINTSFPACGSLKPRELCFPETGLSFRVRENRPP
GTFHQFRLLPVQFLCPNVSVAYRLLGGESLPFRCARDSLEVSTRWALDRERREKYELVAV
CTVRIGAREEEVMVPFLVTVYDEDDSAPTFLGGVDTASAVVEFKRKEGTVVATLRVFDAD
VVPASGELLRRYTSTLLPGDAWALQTFRVEHLPNETLVQANGSFVRATVHDYRLVLNRSL
PISESRELQLAVLVNDSDFQGPGEGILLLHFNVSVLPVSLRLPSAYSFTVSRRARRFAQI
GKVCVENCQEFSGIHVQYKLQLPNANCSALGVVTSAEDTSGTLFVNDTEALRRPECTQLQ
YTVVAADRPTRRQAQAPVLVTVEGTYMAEEPGCPLSCAVSKRRPECEECGGLGSLTGRCE
WRQGDGKGITRNFSTCSPSIRTCPDGHCDAVESRDANVCPQDCLRGGSIIGGHEPGERRG
IKAGFGICNCFPEEKKCFCEPEDSQALLCDELCRTVIAAAVLFSFIVSVLLSTFCIHRYH
KNAHKPPIASAEMTFRRPTQAFPVSYSSAGARRPSLDSMENQVSVDAFKIPEDPKWEFPR
KNLVLGKTLGEGEFGKVVEATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLKQ
VNHPQVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRNSSYLDNP
DERALTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYE
EDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLF
NLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAAS
TPSDSLLYDDGLSEEETPLVDCNNTPLPRTLPSTWIENKLYGMSDPNWPEESPVPLTRAD
GTNTGCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggccggcgccgcggggctgcggttgctgctgctgctgccgctgctc
ggcgaagcccctctgggactctacttctcaagggatgcttactgggagaagctgtatgtg
gaccagccggccggcacacccctgctctatgtccacgccctgcgtgatgtccctgaggag
gtgcccaccttccgcctgggacaacacctctatggtgcctaccgtacgcggctgcacgag
aatgactggatccgcatccaggaggacacgggtcttctttaccttaaccagagcctggac
cacagctcctgggagcagctcagcgtccgcaatgggggcttccccctgctcaccgtctac
ctccaggtctttctgtcgcccacgtccctgcgtgagggcgagtgccagtggccaggctgt
gcccgtgtgtacttctccttcatcaacacctccttcccagcttgtggctccctcaaaccc
cgggagctctgcttccccgagacaggcctctccttccgcgttcgggagaacaggcctcct
ggcaccttccaccagttccgcctgctgcccgtgcagttcctctgccccaacgtcagcgtg
gcctacaggctcctgggaggggagagtctgccattccgctgtgcccgggacagcctggaa
gtgagcacgcgctgggccctggaccgcgagcggcgggagaagtatgagctggtggccgta
tgcacggtgcgcatcggtgcgcgcgaggaggaggtgatggtgcccttcctcgtgactgtg
tacgatgaggacgactcagcgcccaccttcctcgggggcgttgatactgccagcgccgtg
gtggagttcaagcggaaggagggcactgtggtggccacactacgtgtcttcgatgcggat
gtagtgccggcgtctggggagctcctgaggcggtacacaagcacgctgctccctggggac
gcctgggccctccagaccttccgtgtagagcacttgcccaatgagactttggtccaggcc
aacggcagctttgtgcgggccaccgtgcatgactacaggctggttctgaataggagcctc
cccatctcggagagccgcgagctgcagctggccgtgctagtcaacgactcggacttccag
ggccctggtgagggcatcctcctcctccacttcaacgtgtctgtgctgcccgtcagcctg
cgcttgcccagcgcttactccttcaccgtgagcaggcgggcccgccgctttgcccagatt
gggaaagtctgtgtggagaactgccaggaattcagtggcatccatgtgcagtataagctg
cagcttcccaacgccaactgcagtgccctgggggtggtcacctcggctgaggacacctca
gggaccctgttcgtgaatgacacggaggccctgcggcggcccgagtgtacccagctccag
tacacagtggtggccgctgaccggccgacccgcaggcaggcccaggccccagtgctcgtc
accgtggaggggacgtacatggctgaggagccaggctgccccctgtcctgtgcagtcagc
aagaggcggcccgagtgtgaggagtgtggtggcctgggctctctgaccggcaggtgcgag
tggagacagggagatggcaaagggatcaccaggaacttctccacctgctcccccagcatc
aggacctgccccgatggccactgtgacgctgtggagagcagagatgccaatgtctgcccc
caggactgcctccggggcggcagcatcattggtgggcatgagccaggggagcgccggggg
attaaagccggcttcggcatctgcaactgcttccctgaggagaagaagtgcttctgtgag
ccggaagacagccaggctctgctgtgtgacgagctgtgccgcacagtgatcgcggcggcc
gtgctcttctccttcatcgtctccgtgctgctctccaccttctgcatccaccgctaccac
aagaatgcccacaagccgcccatcgcctcagccgagatgaccttccgccggcccacccag
gccttcccggtcagctactcctcggccggtgcccgccggccctcgctggactccatggag
aaccaggtctctgtggacgccttcaagatcccggaggatccaaagtgggaattccctcgg
aagaacttggttcttggaaaaactctgggagaaggcgaatttggaaaagtggtcgaggca
acggccttcaggctaaaaggcaaagctgggtacacgaccgtggctgtgaagatgctgaaa
gagaacgcctccccaagcgagctgcgggacctcctgtcagagttcaacctcctgaagcag
gtcaaccacccacaggtcatcaagctgtacggggcctgcagccaggatgggccactcctc
ctcatcgtggagtatgccaagtatggctccctgcggggcttcctccgggagagccgcaag
gcagggcctggctacgtgggcagtggaggcagccgcaactccagctacctggacaacccc
gacgagcgggccctgaccatgggcgacctcatctccttcgcctggcagatctctcggggg
atgcagtacctggctgagatgaagcttgtccatcgggacttggcagccagaaatgtccta
gtagctgaggggcggaagatgaagatttcggattttggcctgtcccgagacgtttatgag
gaggattcctacgtgaagaggagcaagggtcggattccagtcaaatggatggcaattgag
tccctttttgatcatatctacaccacccaaagtgatgtatggtcctttggtgtcctgctg
tgggagattgtgaccctggggggcaacccctatcctgggattcctcctgagcggctcttc
aaccttctgaagacaggctaccggatggagaggccagacaactgcagcgaggagatgtac
ggtctgatgctgcagtgctggaagcaggagccagacaagagaccagtgtttgctgacatc
agcaaagacctggagaagatgatggttaagagcagagactacttagacctggctgcgtcc
accccatctgactccctgctctacgacgatggcctctcggaggaggagacacccctggtg
gactgtaataatactcccctccctcgaaccctcccctccacgtggattgaaaacaaactc
tatggcatgtcagacccgaactggcctgaagagagtcctgtaccactcacgagagccgat
ggcactaacactgggtgtccgagatatgcaaatgatagtgtatatgctaactggatggtt
tcaccctcagcggcacagttaatggacgcgtttgatagttaa
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