Escherichia coli O6 K2 H1 CFT073 (UPEC): c0089
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Entry
c0089 CDS
T00106
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ecc
Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00290
Valine, leucine and isoleucine biosynthesis
ecc00660
C5-Branched dibasic acid metabolism
ecc01100
Metabolic pathways
ecc01110
Biosynthesis of secondary metabolites
ecc01210
2-Oxocarboxylic acid metabolism
ecc01230
Biosynthesis of amino acids
Module
ecc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ecc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
c0089 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
c0089 (leuC)
Enzymes [BR:
ecc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
c0089 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
c0089 (leuC)
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Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
AAN78585
UniProt:
P0A6A7
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Position
complement(83295..84695)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccacc
atggatcacaacgtctctacccagacgaaagacattaatgcctgcggtgaaatggcgcgc
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtgaccttgccg
gggatgaccattgtctgcggcgactcacataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgggcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattattggtaaaaccggcagcgcaggcggtaccgggcatgtg
gtggaattttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcaaaagccggtctggttgcaccggacgaaaccaccttt
aactatgttaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggagcaactttcgataccgttgtcactctgcaa
gcagaagagatttcgccgcaggtcacctggggcaccaatccaggccaggtgatttctgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgacagaagtggctatcgac
aaagtgtttattggttcctgtactaactcgcgtattgaagatttacgcgcggcagcggaa
atcgccaaaggccggaaagtcgcgccaggcgtacaagcgctggtggttcccggctccggt
ccggttaaagcccaggcggaagcggaaggtctggacaaaatttttatcgaagctggtttt
gaatggcgcttgccaggttgttcaatgtgcctggcgatgaacaacgaccgcctgaatccg
ggcgaacgttgcgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagtccggcaatggctgccgccgcggctgtgaccggacatttcgcc
gacattcgcaacattaaataa
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