Escherichia coli SMS-3-5 (environmental): EcSMS35_3874
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Entry
EcSMS35_3874 CDS
T00672
Symbol
tkrA
Name
(GenBank) 2-ketogluconate reductase
KO
K00090
glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:
1.1.1.79
1.1.1.81
1.1.1.215
]
Organism
ecm
Escherichia coli SMS-3-5 (environmental)
Pathway
ecm00030
Pentose phosphate pathway
ecm00260
Glycine, serine and threonine metabolism
ecm00620
Pyruvate metabolism
ecm00630
Glyoxylate and dicarboxylate metabolism
ecm01100
Metabolic pathways
ecm01110
Biosynthesis of secondary metabolites
ecm01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
ecm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00030 Pentose phosphate pathway
EcSMS35_3874 (tkrA)
00620 Pyruvate metabolism
EcSMS35_3874 (tkrA)
00630 Glyoxylate and dicarboxylate metabolism
EcSMS35_3874 (tkrA)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EcSMS35_3874 (tkrA)
Enzymes [BR:
ecm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.79 glyoxylate reductase (NADP+)
EcSMS35_3874 (tkrA)
1.1.1.81 hydroxypyruvate reductase
EcSMS35_3874 (tkrA)
1.1.1.215 gluconate 2-dehydrogenase
EcSMS35_3874 (tkrA)
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Motif
Pfam:
2-Hacid_dh_C
2-Hacid_dh
NAD_binding_2
GFO_IDH_MocA
Motif
Other DBs
NCBI-ProteinID:
ACB16053
UniProt:
B1LJB3
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All DBs
Position
3943458..3944432
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AA seq
324 aa
AA seq
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MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAAL
LEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVE
VAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAQFGFNMPILYNARRHH
KEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPV
VDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAAC
AVDNLIDALQGKVEKNCVNPHVAD
NT seq
975 nt
NT seq
+upstream
nt +downstream
nt
atgaagccgtccgttatcctctacaaagccttacctgatgatttactgcaacgcctgcaa
gaacatttcaccgttcaccaggtggcaaacctcagcccacaaaccgtcgaacaaaatgca
gcaatttttgccgaagctgaaggcttgctgggttcaaatgagaatgttgatgccgcattg
ctggaaaaaatgccgaaactgcgtgccacatcaacgatctccgtcggctatgacaatttt
gatgtcgatgcgcttaccgcccgaaaaattctgctgatgcacacaccaaccgtattaaca
gaaaccgtcgccgatacgctgatggcgctggtgttgtctaccgctcgtcgggttgtggag
gtagcagaacgggtaaaagcaggcgaatggaccgcgagcataggcccggactggtacggc
actgacgttcaccataaaacactgggcattgtcgggatgggacggatcggcatggcgctg
gcacaacgtgcgcaatttggcttcaacatgcccatcctctataacgcacgtcgccaccat
aaagaagcagaagaacgcttcaacgcccgctactgcgatttggatacactgttacaagag
tcagatttcgtttgcctgatcctgccgttaactgatgaaacgcatcatctgtttggcgca
gaacaattcgccaaaatgaaatcctccgctattttcattaatgccggacgtggcccggtg
gttgatgaaaatgcactgattgctgcattgcagaaaggggaaattcacgccgccgggctg
gatgtcttcgaacaagagccactgtctgtagattcgccgttgctctcaatggccaacgtc
gtcgcagtaccgcatattggatctgccacccatgagacgcgttatggcatggccgcctgt
gccgtggataatttgattgatgcgttacaaggaaaggttgagaagaactgtgtgaatccg
cacgtcgcggactaa
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