Eptesicus fuscus (big brown bat): 103290541 Help Entry 103290541         CDS       T09083                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism efus  Eptesicus fuscus (big brown bat) Pathway efus01524   Platinum drug resistance efus04115   p53 signaling pathway efus04210   Apoptosis efus04215   Apoptosis - multiple species efus04217   Necroptosis efus04620   Toll-like receptor signaling pathway efus04621   NOD-like receptor signaling pathway efus04622   RIG-I-like receptor signaling pathway efus04623   Cytosolic DNA-sensing pathway efus04625   C-type lectin receptor signaling pathway efus04657   IL-17 signaling pathway efus04668   TNF signaling pathway efus04932   Non-alcoholic fatty liver disease efus04936   Alcoholic liver disease efus05010   Alzheimer disease efus05016   Huntington disease efus05022   Pathways of neurodegeneration - multiple diseases efus05132   Salmonella infection efus05134   Legionellosis efus05142   Chagas disease efus05145   Toxoplasmosis efus05152   Tuberculosis efus05160   Hepatitis C efus05161   Hepatitis B efus05162   Measles efus05163   Human cytomegalovirus infection efus05164   Influenza A efus05165   Human papillomavirus infection efus05167   Kaposi sarcoma-associated herpesvirus infection efus05168   Herpes simplex virus 1 infection efus05169   Epstein-Barr virus infection efus05170   Human immunodeficiency virus 1 infection efus05200   Pathways in cancer efus05203   Viral carcinogenesis efus05416   Viral myocarditis efus05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:efus00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     103290541 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     103290541 (CASP8)    04215 Apoptosis - multiple species     103290541 (CASP8)    04217 Necroptosis     103290541 (CASP8)    04115 p53 signaling pathway     103290541 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     103290541 (CASP8)    04621 NOD-like receptor signaling pathway     103290541 (CASP8)    04622 RIG-I-like receptor signaling pathway     103290541 (CASP8)    04623 Cytosolic DNA-sensing pathway     103290541 (CASP8)    04625 C-type lectin receptor signaling pathway     103290541 (CASP8)    04657 IL-17 signaling pathway     103290541 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103290541 (CASP8)    05203 Viral carcinogenesis     103290541 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     103290541 (CASP8)    05161 Hepatitis B     103290541 (CASP8)    05160 Hepatitis C     103290541 (CASP8)    05164 Influenza A     103290541 (CASP8)    05162 Measles     103290541 (CASP8)    05168 Herpes simplex virus 1 infection     103290541 (CASP8)    05163 Human cytomegalovirus infection     103290541 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     103290541 (CASP8)    05169 Epstein-Barr virus infection     103290541 (CASP8)    05165 Human papillomavirus infection     103290541 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     103290541 (CASP8)    05134 Legionellosis     103290541 (CASP8)    05152 Tuberculosis     103290541 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     103290541 (CASP8)    05142 Chagas disease     103290541 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     103290541 (CASP8)    05016 Huntington disease     103290541 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     103290541 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103290541 (CASP8)    05416 Viral myocarditis     103290541 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     103290541 (CASP8)    04932 Non-alcoholic fatty liver disease     103290541 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     103290541 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:efus01002]     103290541 (CASP8) Enzymes [BR:efus01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      103290541 (CASP8) Peptidases and inhibitors [BR:efus01002]  Cysteine peptidases   Family C14: caspase family    103290541 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED DUF3837 Motif Other DBs NCBI-GeneID:  103290541 NCBI-ProteinID:  XP_054579175 LinkDB All DBs Position 11:complement(84755419..84784092) Genome browser AA seq 489 aa AA seqDB search MSFSSCLYEIGEALSSDEVASLKFLSLDYIPPRKQEPIKDALMLFEKLQEKRMLEESNLS FLRELLYRIDRLDLLAKGLKTSKEEMRKELQIPGRAQISAYRVMLFQISEDVTAQELKDF KFFLSQELSRCKLADSMSLLDIFMEMEKRLILGERNLDTLKRICKQINLSLLDKISAYEE LSKEGGPISDYPQEQDSESQKQNCELPREQNCESREQDCEPKQTADKVYRMKSKPRGYCV IFNNYDFSKARENVPKLHIIKDRTGTDMDAEALHNTFSELHFEVVAYKDATAKEICEILK NYQSKDHSDKDCFICCILSHGDKGIVYGCDGQEASIYELTSYFTGLKCPSLAGKPKIFFI QACQGDNFQKGIAVETDSEEKEAYLEMDSYQKRNIPDEADFLLGMATVNNCVSYRNPEKG SWYIQSLCQSLRERCPRGDDILTILTEVNFEVSSKDVCSKDRKKDKKNIWKQMPQPTFTL RKKLYFPLN NT seq 1470 nt NT seq  +upstreamnt  +downstreamnt atgagtttcagcagttgtctgtatgaaattggggaagcgctgagcagcgatgaggtggcc tcgctcaagttcctgagcctggactacatcccaccaaggaagcaggagcccatcaaggac gccttgatgctcttcgagaaactccaggagaagagaatgctggaggaaagcaacttgtcc ttcctgagggagctgctataccgaatcgacaggctggatctgctggcaaagggcctgaag accagcaaggaggagatgcggaaggagcttcagatcccgggccgggctcagatctctgcg tacagggtcatgcttttccagatttcagaagatgtgactgcacaggaattgaaggacttt aagttttttttgagccaggagctctccagatgcaaactggcggatagcatgagcttgctt gatattttcatggagatggagaagagactcatccttggggaaagaaatttggacacccta aaaagaatctgtaaacaaatcaacctgagcctgctggataaaatcagtgcttatgaagaa ttaagtaaagagggggggccaatttcagactatcctcaagagcaggacagtgagtcccag aaacagaactgtgagctgccacgggaacagaactgtgagtcccgggagcaggactgtgag ccgaagcagacagcggacaaagtttaccgaatgaaaagcaaacctcgaggatactgtgtg atctttaacaattatgattttagcaaagcccgggagaacgtgcccaaacttcacataata aaggatagaactggaacagacatggatgcagaggctttgcacaacacctttagtgagctt cattttgaggtagtggcttacaaagacgccacagcaaaggaaatctgtgagatcctgaag aactaccaaagcaaggaccacagtgacaaagactgcttcatctgctgcatcctttcccat ggagacaagggcatcgtctacggctgcgatgggcaggaagcctccatctatgagctgacc tcttacttcactggtttgaagtgcccttcccttgcaggcaaaccgaaaatcttttttatc caggcttgtcaaggggataactttcagaaaggcatagctgtggagaccgactcagaagag aaggaagcctatttagaaatggactcatatcagaagagaaatatccccgatgaggctgac tttctgctggggatggccactgtgaacaactgtgtttcctaccgaaaccccgaaaagggg tcctggtatatccagtcactgtgccagagtctgagagaaagatgtcctaggggtgatgac attctcaccatcctcactgaggtcaactttgaagtgagcagtaaggacgtgtgcagtaag gacaggaagaaagacaagaagaatatttggaagcagatgccacaacccactttcacgctg agaaaaaaactctacttcccccttaattga

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