Eptesicus fuscus (big brown bat): 103295001 Help Entry 103295001         CDS       T09083                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism efus  Eptesicus fuscus (big brown bat) Pathway efus04010   MAPK signaling pathway efus04014   Ras signaling pathway efus04015   Rap1 signaling pathway efus04022   cGMP-PKG signaling pathway efus04066   HIF-1 signaling pathway efus04068   FoxO signaling pathway efus04072   Phospholipase D signaling pathway efus04150   mTOR signaling pathway efus04151   PI3K-Akt signaling pathway efus04152   AMPK signaling pathway efus04211   Longevity regulating pathway efus04213   Longevity regulating pathway - multiple species efus04520   Adherens junction efus04910   Insulin signaling pathway efus04913   Ovarian steroidogenesis efus04923   Regulation of lipolysis in adipocytes efus04930   Type II diabetes mellitus efus04931   Insulin resistance efus04932   Non-alcoholic fatty liver disease efus04960   Aldosterone-regulated sodium reabsorption efus05010   Alzheimer disease efus05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:efus00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103295001 (INSR)    04014 Ras signaling pathway     103295001 (INSR)    04015 Rap1 signaling pathway     103295001 (INSR)    04066 HIF-1 signaling pathway     103295001 (INSR)    04068 FoxO signaling pathway     103295001 (INSR)    04072 Phospholipase D signaling pathway     103295001 (INSR)    04022 cGMP-PKG signaling pathway     103295001 (INSR)    04151 PI3K-Akt signaling pathway     103295001 (INSR)    04152 AMPK signaling pathway     103295001 (INSR)    04150 mTOR signaling pathway     103295001 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     103295001 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103295001 (INSR)    04923 Regulation of lipolysis in adipocytes     103295001 (INSR)    04913 Ovarian steroidogenesis     103295001 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103295001 (INSR)   09149 Aging    04211 Longevity regulating pathway     103295001 (INSR)    04213 Longevity regulating pathway - multiple species     103295001 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     103295001 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     103295001 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103295001 (INSR)    04932 Non-alcoholic fatty liver disease     103295001 (INSR)    04931 Insulin resistance     103295001 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:efus01001]     103295001 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:efus04090]     103295001 (INSR) Enzymes [BR:efus01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      103295001 (INSR) Protein kinases [BR:efus01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    103295001 (INSR) CD molecules [BR:efus04090]  Proteins   103295001 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  103295001 NCBI-ProteinID:  XP_008149624 LinkDB All DBs Position 6:6518257..6672212 Genome browser AA seq 1378 aa AA seqDB search MGPGGARGAAAPLLLAALTALLVGAAGHLYPGEVCPSMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLRDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDVCPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTSCKSHGCTAEGLCCHNECL GSCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCLDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCAPCLGPCPKVCHILEGKKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLRLIQGNTL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEISGTKGRQE RTDIALKTNGDQASCENELLKFSYIRTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYR NVTEFDGQDACGSNSWTVVDIDPPMRSNDAKSQKHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYIQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPSELEGPQKHNQSEHDEAAGQCCTCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKTSAGPGAEDSRPSRRRRALGDEGNVTTAVPTAPGS PNTSTIVPTSSEAPRPFEKVVNKESLVISGLRHFTGYRIELQACNQDFPEERCSVAAYIS ARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVS RRHYALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTNYLDVPSNIAKIIIGP LIFVFLFSVVIGSIYLFLRKRQSDGPVGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE KITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESATMRERIEFLNEASVMKGF TCHHVVRLLGVVSKGQPTLVVMELMTHGDLKSHLRSLRPDAENNPGRPPPTLQEMFQMAA EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR WMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDIPDNC PERLSELMSMCWHFNPKMRPTFLEVVDLLKDNLHPSFPEVSFFYSEENKAPCEHEELEME FEDMESVPLDRSSHCQREEDGGCSLALKRNYEEPMSYTHMNGGKKNGRVLTLPRSSPS NT seq 4137 nt NT seq  +upstreamnt  +downstreamnt atgggccctgggggcgcgcggggggccgcggccccgctgctgctggcggcgctgaccgcg ctgctggtgggcgccgcgggccacctgtaccccggagaggtgtgccccagcatggatatc cggaacaacctcacgaggctgcacgagctggcgaactgctcggtcatcgaaggacacttg cagatcctgttgatgttcaaaacgaggcccgaggacttccgagacctcagtttccccaaa ctcatcatgatcaccgattacttgctgctgtttcgggtctatgggctggagagcctgagg gacctgttccccaacctcacggtcatccggggctcccgtctcttcttcaactacgcgctg gtcatcttcgagatggtgcacctgaaggagctgggcctctacagcctcatgaacatcacc cggggctccgtccgcatcgagaagaacaacgagctctgctacctggccaccatcgactgg tcgcgcatcctggactcggtggaggacaactacatcgtgctgaacaaagacgacaacgag gagtgtggggacgtctgtccgggcaccgcaaagggcaagaccagctgccctgccactgtc atcaatgggcagtttgtcgaacggtgctggactcacagccactgccagaaagtctgcccg accagctgtaagtcgcacggctgcactgctgagggcctctgctgccacaacgagtgcctg ggcagctgctctgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg gacggtaggtgcgtggagacctgcccgccgccctactatcacttccaagactggcgctgt gtgaacttcagcttctgcctggacctgcacaacaaatgcaagaactcgcggaggcagggc tgccatcagtacgtcatccacaacaacaagtgcattcctgagtgtccctccgggtacacc atgaactccagcaacttgatgtgcgctccgtgcctgggcccctgtcccaaggtctgtcac atcctggaaggtaagaagaccatcgactcagtgacatctgcccaggagcttcgaggatgc accgtcatcaacgggagcctcatcatcaacattcgtgggggcaacaacctggcagctgag ctggaggccaacctcggcctcattgaagagatttcagggtttctgaagatccgccgttcc tacgcgctggtgtcgctctccttcttccggaagttacgcctgattcaggggaataccttg gaaattgggaactactctttctatgccttggacaaccagaacctaaggcagctatgggac tggagcaaacacaacctcaccataactcaggggaaactcttcttccactataatcccaaa ctctgcttgtcggaaattcacaagatggaagaaatttcaggaaccaagggtcgccaggag aggaccgacattgccttgaagactaacggggaccaggcatcctgtgaaaatgaattactt aaattttcttacattcggacatcttttgacaagatcttgctgaaatgggagccgtactgg ccccctgacttccgagacctcctggggttcatgctcttctacaaagaggccccttatcgg aatgtgacggagtttgatgggcaggatgcgtgtggatccaacagctggacggtggtggac attgacccgcctatgaggtccaatgacgctaagtcacagaagcatcctgggtggctgatg cggggtctcaagccctggactcagtacgccatcttcgtgaagaccttggtcaccttttct gatgaacgtcgcacgtatggggccaagagcgatatcatctatatccagacagatgccacc aatccttccgtccccttggatcccatctcggtttctaactcttcatcccagattatcctg aagtggaagcctccctctgaccccaacggcaacatcacacactacctggttttctgggag aggcaggcggaagacagcgagctgtatgagttggattattgcctcaaagggctgaagctg ccctcccggacctggtccccgccctccgagctggaaggtccccagaagcacaaccagagc gagcacgacgaggcggccggccagtgctgcacctgcccgaagacggactctcagatcctg aaggagctggaggagtcctcgttcaggaagacgtttgaggattacctgcacaacgtggtc ttcgtccccagaaaaacctctgcaggtcctggtgctgaggacagtaggccatcgagaaga cgtagggcccttggtgacgaggggaacgtgacgacggctgtgcccacagctccgggttcc cccaatacctcaaccatcgtgcccaccagctcggaggcgccccggcccttcgagaaagtg gtgaacaaggagtcgctggtcatctctggcctgcgccacttcactggctaccgcatcgag ctgcaggcctgcaaccaagacttccccgaggagaggtgcagcgtggcggcctacatcagc gccaggaccatgcccgaagccaaggcagatgacattgtcggccccgtgacccatgaaatc ttcgagaacaacatcgttcatttgatgtggcaggagccgaaggagccgaacggtctgatt gtgctgtatgaagtgagttatcgacgatacggagacgaggagctgcacctgtgtgtgtcc cgcaggcactacgccctggagcggggctgcaggctgagggggctgtcccccgggaactac agcgtgagagtacgggccacctccctggcgggcaatggttcctggacagaacccacctat ttctatgtgacaaactacttagacgtcccatccaatattgcaaaaattatcatcggcccc ctcatctttgtcttcctcttcagtgttgtgattggaagcatttacctgttcctgaggaag aggcagtcagatgggccggtgggaccgctctatgcttcttcaaaccccgagtacctcagt gccagcgatgtgttcccgtgttctgtgtatgtgccggacgagtgggaggtgccgcgggag aagatcaccctcctgcgcgagctgggccagggctccttcggcatggtgtacgagggcaac gccaaggacatcatcaagggcgaggcggagacccgcgtggcggtgaagacggtcaacgag tcggccaccatgcgggagcggatcgagtttctcaacgaggcctccgtcatgaaaggcttc acctgccatcacgtggtccgcctcctcggggtggtgtccaaaggccagcctacgctggtg gtgatggagctgatgacgcacggagacctgaagagccacctccggtccctgcggcctgat gctgagaataaccccggccgccctcccccgaccctgcaagagatgtttcagatggcagca gagatcgccgacgggatggcatacctgaatgccaagaagtttgtgcaccgggacctcgca gctcgaaactgcatggtcgcccacgattttaccgtcaaaatcggagactttggaatgacc agagacatctacgaaacggactattaccggaaaggcggcaaagggctgcttcctgtgagg tggatggcacctgaatccttgaaggacggggtctttaccgcttcttccgacatgtggtcc ttcggcgtggtgctctgggaaatcaccagcttggcagagcagccttaccaaggcctctcc aatgagcaggtgctgaagttcgttatggatggagggtatctggacatccctgacaactgt ccagagagactcagcgaattgatgagcatgtgctggcatttcaatcccaagatgaggccg accttcctggaggtcgttgacctgctgaaggacaacctgcaccccagctttccggaagtt tccttcttctacagcgaggagaacaaggcaccttgtgagcacgaggagttggagatggag tttgaggacatggagagtgtacccctggatcggtcctcacactgtcagagggaggaggat gggggatgttcgctggccctaaagcggaattacgaggagcccatgtcctacacccacatg aacgggggcaagaaaaacggacgcgtcctgactctgccacggtccagtccttcctaa

DBGET integrated database retrieval system