Eumetopias jubatus (Steller sea lion): 114226156
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Entry
114226156 CDS
T07240
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju00310
Lysine degradation
eju01100
Metabolic pathways
eju05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
114226156 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
114226156 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
eju03036
]
114226156 (DOT1L)
Enzymes [BR:
eju01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
114226156 (DOT1L)
Chromosome and associated proteins [BR:
eju03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
114226156 (DOT1L)
HMT complexes
Dot1-containing complex
114226156 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
114226156
NCBI-ProteinID:
XP_027981875
LinkDB
All DBs
Position
Unknown
AA seq
1705 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDNKSTTATPTKLP
ESKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALRTQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDALSAHLRGKGALGRELEADPGRLHLDLDCSKFSLSHLNSASPELSMNGHAASY
EVCGALSRPSSKQNTPQYLASPLDQEVIPCTPSHSSRPRLEKMSGLALPDYTRLSPAKLV
LRRHLSQDHVASGKTAANELHPRAEHAKENGLPYQSPGIANGIKLSPQDPRPSSPMALQM
TGERGGEKGVKERAYASTGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGTNAHGAGSKGLTPAPAGFYAGSVAVSGALAGSPAPLAPGAE
PGTFDEVSGSGSLFASMGSCSTPQHPPLLPQSRGSGAASPAHPLCTSPRLSSAAQGPLPE
ASKGDLPSEAGFSDPEGEAKRRIVFTISAGGSAKQSPPGKPSPLPTGARGDSGQGHGPDS
RKRGRRKRAAAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAI
SSPESLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSARIERKI
ATISLESKSPPKTLESGGGLAGRKPTPASEPANSSKWKSTFSPISDLGLAKCADSPLQAG
STLSQNSLFAFRPPLEEPGLADAKLAAHPRKSFSGALSGAGGLSPSSNPPNGFAFSGGLA
ADLSLHSFSDGASLSHKVPEAASLGAPLSFPAPRGKEGGATEPGAFVNKRQLDGLGGPKG
REAGELGLPACGPPDKASLVHSKPGKGRDREPDLKNGHNLFISAATVPPGGLLSGPGLAT
AASSAVSAAPSAQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVPAAAGLVHV
SSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSATLSLTP
LQAVAGAPASSFQAPPPPPPGQPALPAPPPPNAALPPAPALLPANSEPVLLQNLASLPAN
QAFLSTSSAASLQPANASLSIKLASLPHKAPRPSFTVHHQPLPGLALAQAAPVIPQASST
GPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5118 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaagagatcccagacctcaagcttgctatggagaattatgttctg
atcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaaatacaaccgc
gccatcgacagcatccaccagctgtggaaggggaccacgcagcccatgaaactgaacact
cggccgtccaacgggctcctgcggcacatcctgcagcaggtctacaaccactcggtgacg
gaccctgagaagctcaacaactacgagcctttctcccccgaggtgtacggggagacctcc
tttgacttggtcgcacagatgatcgacgagatcaagatgaccgaggacgacctgtttgtg
gacctgggcagtggagtgggccaggtcgtgctgcaggtcgcggcggctaccaactgcaaa
catcactatggcgtagagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggcgacttcctctcggaagagtggagagagcggattgccaacacaagtgttatatttgtg
aataattttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcgaacatg
aaggaaggcggcagaatcgtgtcctcgaagccctttgcgcctctgaacttcagaataaac
agcagaaacttgagtgacattggcaccatcatgcgcgttgtggagctctccccgctgaaa
ggctcggtgtcctggacggggaagccggtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaagcg
gcccggcgccggcagcagcgagacaacaagagcaccacggccactcccaccaagctgccc
gagagcaaggctgctgtgcccgcggacaccccgatggattccggggccgaggaagaaaaa
gctggggcgaccaccatcaaaaagccgtccccctccaaagcccggaagaagaagctgaac
aagaaggggcggaagatggccggccggaagcgcgggcgtcccaagaagatgagcactgcg
aacccggagcgtaagcccaagaagagccaaactgcactggacctcctgcatgcccaggcc
gcgtcgcagacggcagcgccctcgccgcaggatgcgtacaagtcacctcatagcccgttt
tatcagctacctcccagtgtgcagcggcacccccccgaccagctgctgctggcacccacc
ccgcccgcactgcagaagctgctagaatccttcaagattcagtacttgcagttcttggca
tacaccaagacagcccagtacaaggccagcttgcagcagctgctggaccaggagaaggag
aagaacgcccggttgctaggtgctgcgcagcagctgttcggccactgccaggcccagaaa
gaggagatcaagaggctcttccagcagaaactggatgagctgggtgtgaaggcgctgacc
tacaacgacctgatccaggcacagaaggagatttcggctcacaaccagcagctgagggaa
cagacggagcagctgcagaaggacaacagggagctgagaagccagagcctacagctgctc
aaggctcggtgtgaggagctgaagctggactggtccacgctgtccctggagaacttgctg
aaggagaagcaggccctgaggacccagatctctgagaagcagaggcactgcctggagctg
cagatcagcattgtggaactggagaagagccagcggcagcaggagctcctgcagctcaag
tcttgcgtgccgccggatgacgccctgtctgcgcacctgcgcgggaaaggagccctgggc
cgggagctggaggctgaccccggccggctgcatctggacctggactgctccaagttctcc
ctgtcccacttgaacagcgcaagcccagaactctccatgaacggccacgcagctagctat
gaggtgtgcggcgcgctgagccggccctcgtccaagcagaacaccccccagtacctggcc
tcccccctggaccaggaagtcataccctgcacccccagccacagcagccggccgaggctc
gagaagatgtcgggcctggcgttgcccgactacacccggctctccccggccaagctggtg
ctgaggcggcacctgagccaggaccacgtggccagtggaaagacggcggccaatgagcta
cacccgcgagctgagcacgccaaggagaacggccttccataccagagccctggcattgca
aacggcatcaagctgagccctcaggaccctcgaccctcgtcccccatggccttacagatg
acaggggagaggggcggcgagaagggtgtgaaggagcgcgcctatgccagcactggggag
gccatcaccagcttgcccgtcagcatcccgctcagcaccgtgcagccgagcaagctgccc
gtcagcatccctctggccagtgtggtgctgcccagccgtgccgagaaagtgagaagcacc
cccagccctgtgccgcagacccgagagtcctcgtccacacttgaaaagcagatgggcact
aatgcccacggcgctggaagcaaaggcctcaccccagctcctgcaggcttctacgcgggc
tcagtggctgtcagtggggccctggcaggcagcccggcccccctcgctcccggagccgag
cccggcaccttcgatgaggtctcgggctcaggaagcctgttcgccagcatggggtcctgc
tccaccccgcagcacccacccctgctgccgcagtcccgcggctccggtgcagcctcgcct
gcccatccgctctgcaccagcccccggctcagcagtgctgcccagggcccgctccccgag
gccagcaaaggggaccttccttccgaggccggcttttcagaccctgagggcgaagccaag
aggaggatcgtctttaccatctcggctggcggcagtgccaaacagtcgcctcccggcaaa
ccgagccctctgcccacgggcgcccgtggggacagtggccagggccatgggccagacagc
cgcaagcggggcaggaggaagcgggcggcagctgggacccccagcctgagctccggcgtg
tcgcccaagcgtcgggctctgccgtccgttgccggcctcttcacacagtcttcagggtcc
ccgctgaacctcaactctatggtcagcaacattaaccagcctttggaaatcacggccatc
tcgtcccccgagagcctgaagagctcccctgtcccttaccaggacaacgaccagccgccc
gttctcaagaaggagaagccgttgagccagaccaatggggcccactactccccactgacc
tcagacgaggagcagggctctgaggatgagccaggcagcgccagaatcgagagaaaaatt
gcaacaatctccttagaaagcaaatctcctccaaaaaccttggaaagcggtggtggcctg
gccgggaggaagccgacccctgccagcgagcccgccaacagcagcaagtggaaatccacc
ttctcgcccatttccgacctcggcctggccaagtgcgccgatagcccgctgcaggctggc
tccaccctgagccagaactccctgttcgctttccgaccccctttagaggagcccggcttg
gctgatgccaagctggctgcccaccccaggaaaagcttttctggtgccctgtcgggggcc
ggtgggctaagccccagcagcaaccctcccaacggcttcgccttcagcgggggcctggcc
gccgacctcagtttacacagcttcagcgatggtgcttctctctcccacaaggtccccgag
gcggccagcctgggcgcccctttgagcttccctgccccgcggggcaaggagggcggtgcc
acagagcccggcgcctttgtgaacaagaggcagctggatggactgggcggccccaagggc
agggaggccggcgagctgggcctgccggcgtgcgggcccccggacaaggcctcgctggtg
cacagcaagccgggcaagggccgggaccgtgagcccgacttgaagaatggccacaacctc
ttcatttctgccgccactgtgcctcccgggggcctcctcagcggcccgggcctcgccacg
gcggcgtcctcggcggtcagcgcggccccctccgcccagacacaccgccccttcctgggc
acctttgcccccggcccacagttcgccctgggtcccatgtccctgcaggccaacctgggc
tcatccgtgctacagtccttgttcagttccgtgccggccgctgccggcctggtgcacgtc
tcgtccgctgcaaccagactgaccaactcgcacgccatgggcagcttttcctccggggtg
gcaggtggcgcagttggaggtgtctttaaccacgcggtgccttccgcctccgctcatccg
tttggagccagtttcggcagcggggctgcgtgtcgcagcgccacgctgagcttaacccca
ctgcaggcggtggccggcgcccccgcgtcttcctttcaggccccgcccccgcccccaccg
gggcagcccgccctccccgcaccccctccccctaacgccgccttgcctcctgcccccgcg
ctgctcccggctaactctgagcccgtgcttctgcagaacctcgcgtccctcccggctaac
caggctttcttatccacctcctctgccgcctctctgcagcctgctaacgcctctctgtcc
atcaagctcgcctccctcccgcacaaggccccccgcccctccttcacggtgcaccaccag
cccctgcccgggctggccctggcccaggccgcgcccgtgatcccgcaggccagctccacg
gggccgtctgccgtgtgggtttcccttggcatgccgcctccgtatgccgcgcgccttgcg
ggggttaagccaagataa
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integrated database retrieval system
