| Entry |
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| Name |
(RefSeq) multidrug resistance-associated protein 4 isoform X1
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
elk Enhydra lutris kenyoni (northern sea otter)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:elk00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
111146955
09132 Signal transduction
04024 cAMP signaling pathway
111146955
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
111146955
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
111146955
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:elk02000]
111146955
Transporters [BR:elk02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
111146955
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1325 aa
MLPVYPDVKPNPLQNANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSKHLGEEL
QGCWDKEVSRAEKDARKPSLTKAIIKCYWKSYVVLGVFTLIEEGTKIIQPIFLGKIINYF
ENHDPTNAVALHEAYIYATVLTVCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYQKALR
LSNVAMGKTTTGQIVNLLSNDVNKFDQVTMFLHFLWAGPLQAIAVTALLWMEIGISCLAG
IAVLIILLPLQSCIGKLFSSFRSKTAAFTDVRIRTMNEVITGIRIIKMYAWEKSFADLIT
HLRRKEISKILSSSYLRGMNLASFFVASKIIIFVTFTTYVLLGNVITASHVFVVVSLYGS
VRLTVTLFFPAAIEKVSEAVISIQRIKNFLLLDEISQRTPQRPSDGKTIVHVQDVTAFWD
KTSETPTLQDLSFTVRPGELLAVIGPVGAGKSSLLSTVLGELPRSRGLVSVHGRIAYVSQ
QPWVFSGTVRSNILFGKKYEKERYEKVIKACALRKDLQLLEDGDLTVIGDRGATLSGGQK
ARVNLARAVYQDADIYLLDDPLSAVDAEVGRHLFELCICQTLHEKITILVTHQLQYLKAA
SQILILKDGKMVQKGTYTEFLKSGVDFGSLLKTENEEADQSPAPGSPVLRTRSFSESSIW
SQQSSRPSLKDGVQEVQENENTPAAVSEESRSEGKVGFKAYKNYLAAGAHWLVIVFLVLL
NVIAQVAYVLQDWWLSYWANEQSALNVMVNGTENVTEKVDLAWYLGIYSGLTVATVLFGI
VRSLLVFYVLVHSSQTLHNKMFESILRAPVLFFDRNPTGRILNRFSKDIGHMDDLLPLTF
LDFLQTFLQVLGVVGVAVAVIPWITIPLIPLGILFFVLRWYFLETSRDVKRLESTTRSPV
FSHLSSSLQGLWTIRAYKAEERFQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFV
IIIAFGSLILATTVDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVMEYTDLE
KEAPWEYQNRPPPNWPQDGTIVFDNVNFSYSLDGPLVLKHLTALIKSKEKVGIVGRTGAG
KSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNE
HTDEELWNALTEVQLKEAIEELPGKLDTELAESGSNFSVGQRQLVCLARAILRRNRILII
DEATANVDPRTDELIQKKIREKFAQCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYV
LLQNEESLFHKMVQQLGKAEAAALTETAKQEYFKRNYPDITHRDHVVMNASNGQPSAFTI
FETAL |
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| NT seq |
3978 nt +upstreamnt +downstreamnt
atgctgcccgtgtacccggacgtgaagcccaacccgctgcagaacgctaacctctgctcg
cgcgtgttcttctggtggctgaaccccttgtttaaaattgggcacaaacggaggttagag
gaagatgacatgtattcggtgcttccagaagatcgctcgaagcatctgggagaggagttg
caagggtgctgggataaagaagtttcgagagccgagaaagatgcacggaagccttcttta
acgaaagccatcataaagtgttactggaaatcctatgtagttctgggagtttttacgctc
attgaggaaggcaccaaaataatccagcccatatttttggggaaaattattaattatttt
gaaaaccatgatcctactaatgctgtggctttgcacgaagcctatatctacgccacggta
ctgactgtctgcacgcttatcctggccatactgcaccatctgtacttctaccacgttcag
tgcgcgggcatgaggctgcgcgtcgccatgtgtcacatgatttatcagaaggcgcttcgc
ctcagtaacgtggccatggggaagacgaccaccggccagatcgtcaatctgctgtccaac
gacgtgaacaagttcgaccaggtgacaatgttcttgcactttctgtgggcagggccactg
caggcgatcgcagtgactgccttgctctggatggaaatcggaatatcctgtcttgcgggg
atcgcagtcctcatcatccttctgcccttgcaaagctgcattgggaagttgttttcatca
ttccggagtaagaccgcagccttcacagacgtcaggatcaggaccatgaatgaggttata
actggcataagaataataaaaatgtatgcttgggagaagtcatttgcagaccttatcacc
catttgagacggaaggaaatttccaagattctgagcagttcctacctcagaggaatgaat
ttggcgtcatttttcgttgcaagcaaaatcatcattttcgtgactttcaccacctatgta
ctccttggcaacgtgatcacagcaagccatgtgttcgtggtggtgtcgctgtatggctct
gtgcggctgaccgtcaccctcttcttccccgcggccattgagaaggtgtccgaggcggtc
atcagcatccaaagaatcaagaactttctgttgcttgacgagatctcacagcgcacccct
cagcggccatcagatggtaaaaccatagtgcacgtgcaggacgtcactgccttttgggat
aagacatcagaaacgccaaccctacaagacctttcctttactgtgagaccgggggaattg
ttagcagtgatcggacctgtgggagcaggaaagtcgtcgctgttgagcaccgtcctcggt
gagctgccccggagccgggggctggtcagcgtgcatggaaggatcgcctacgtttctcag
cagccctgggtgttttcgggaactgtgaggagtaacattttatttgggaagaaatatgag
aaggaacgatacgagaaagtgataaaggcctgcgctttgagaaaggatttgcagcttttg
gaggacggagatttaaccgtgataggtgatcggggagccacgctgagcggggggcagaag
gcccgcgtgaacctcgccagagcagtgtatcaggacgcggacatctacctcctggacgat
cctctcagtgcagtggacgcagaagttggccggcacttgtttgaactgtgtatttgtcaa
accttgcacgagaagatcacaatcttagtgactcaccagttgcagtacctaaaagctgca
agtcagattctgatattgaaagatggcaagatggtacagaaggggacttacacggagttt
ctgaaatctggggtggatttcggctcccttttaaagacggagaacgaggaggctgaccag
agtcctgctccaggatctcccgtcctgaggactcggagcttctccgagtcttccatttgg
tcccagcagtcgtccagaccctcgctgaaagacggcgtgcaggaggtccaggagaacgag
aacacaccggctgctgtgtccgaggagagtcgttcagaaggaaaagtcggttttaaggcc
tacaagaattacctagcggccggcgctcactggctggtcattgtgttcctcgttctgtta
aacgtcatagctcaggtcgcctacgttcttcaggactggtggctctcctactgggcaaat
gaacaaagtgccctgaatgtcatggtaaatggaacagaaaatgtcactgagaaggtcgat
cttgcctggtacttaggaatttactcaggtttaacggtggctactgtcctttttggcata
gtgagatctcttttggtattctatgtcctcgttcattcttcgcaaactctgcacaacaaa
atgttcgagtccattctgagagctccggtgttgttctttgatagaaacccaacaggaaga
attttaaatcgtttctccaaagacattgggcacatggatgacttgctacccctgacgttt
ctagatttcctccagacatttctacaagttcttggtgtggtgggtgtggcggtggctgtc
attccgtggatcacaattcctctgattccccttggcatccttttctttgttcttcggtgg
tatttcttagaaacgtcgagagatgtcaaacgcctggaatctacaacacggagtccggtg
ttctcccacttgtcgtcctctctccagggactctggaccatccgggcatataaagctgag
gagaggttccaggaactattcgatgctcaccaggatttgcattcagaggcatggttcttg
ttcctgacgacgtcccgatggttcgccgtacgtctggatgccatctgcgccatctttgtc
attattattgcctttgggtccttgattctagcaacgactgtagatgctgggcaggttggc
ctggcgttgtcctacgccctcaccctcatggggatgttccagtggtgcgtccggcagagc
gccgaagtggagaatatgatgatttcagtggaaagggtgatggagtatacagaccttgag
aaagaagccccttgggagtaccagaaccgccctccgcccaactggccccaagacggcacg
atcgtctttgataacgttaacttctcctacagtttagatgggcctctggttttgaagcac
ctgacagcactcattaaatcaaaggaaaaggtcggcattgtgggaagaacaggagctgga
aaaagttccctcatctcggccctttttaggttgtcagaaccggaaggtaaaatttggatt
gataaaatcttgacaactgaaattgggcttcacgatttaaggaagaaaatgtccatcata
cctcaggaacctgttttattcactggaacaatgaggaaaaatctggatccctttaatgag
catacggatgaggaactatggaatgccttaacagaggtacagcttaaagaagccattgaa
gaacttcctggcaaattggacaccgaattagcagaatcgggatcgaacttcagtgttgga
cagagacagctggtgtgcctcgccagggccatcctcaggagaaaccggatattgatcatt
gatgaagcgacagcaaacgtggatccaagaactgacgaattaatacaaaaaaaaatccgt
gagaaatttgcccagtgcaccgtgttaaccattgcccacaggttgaacaccattattgac
agtgacaagatcatggttttggattcaggaagactgaaggagtatgatgaaccctatgtt
ttgctgcagaatgaagaaagcctgtttcacaagatggtacagcagctgggcaaggcagaa
gctgctgctctcaccgaaacagcaaaacaggagtatttcaaaaggaattacccagatatt
actcacagagaccacgtggtcatgaatgcttccaatggacagccctcagccttcactatt
tttgagacagcactgtga |
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